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Protein Overview: KTR3

General Information:
Name(s) found: KTR3 / YBR205W [SGD]
Description(s) found:
Found 26 descriptions.
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  • Putative alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 404 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [ISSLink to PubMed article]
    Biological Process: protein amino acid O-linked glycosylation [IMPLink to PubMed article]
    cellular cell wall organization [IMPLink to PubMed article]
    protein amino acid N-linked glycosylation [IMPLink to PubMed article]
    Molecular Function: mannosyltransferase activity [IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSVHHKKKLM PKSALLIRKY QKGIRSSFIG LIIVLSFLFF MSGSRSPEVP IAQGTSVSRV  60
   61 ASKDYLMPFT DKSQGVIHPV DDGKKEKGVM VTLARNSDLW NLVKSIRHVE DRFNNRYHYD 120
  121 WVFLNDQPFS DEFKRVTSAL VSGKAKYGTI PKDHWSIPSW IDTEKFDEKR LAMGKLDIPY 180
  181 GSSVPYRHMC RFQSGFIWRH PLLEEYEWFW RVDTDITLFC DIQYDIFKFL KVNNKKYGFI 240
  241 LSVSEYERTI PTLWETTKKF IKKNPKFLHK NNLMKFISND DGDTYNMCHF WTNFEIGSLD 300
  301 FFRSDAYREY FDYLDSSGGF FYERWGDAPV HSIAASLFLD KSEIHFFDGL GFHHPDFTSC 360
  361 PIEQKIRLQN KCICEPSKDV TWTPDYFCTR KYFSAGNYKL PPGI

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) KAP104 KTR3
    View Details Gavin AC, et al. (2006) KTR3 MRI1 RPL4A SVF1
    View Details Gavin AC, et al. (2002) ADH1 CCT4 CSE1 DHH1 DUG1 ECM29 FKS1 GCN1 GCN20 GFA1 IDH2 KAP123 KTR3 MIR1 RGR1 SAM1 SEC7 SLC1 SRV2 YHR020W
    View Details Ho Y, et al. (2002) ADH4 ADR1 ARC1 AYR1 BGL2 CBP6 ENP1 FAA1 GAR1 GSP1 HEM15 HRP1 HTA2 KAP104 KTR3 MNN9 MRT4 NAB2 NDE1 OAC1 PAA1 PET10 PET9 PSD1 RPT4 RTN2 SAC1 SLC1 TFG2 VAN1 VMA8 WBP1 YDL063C YHM2 YNL035C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run VAM3 Sample: HX14 - mixture in detergent (control). Hao Xu, et al. (2010)
    View Run MLP2 #20 Asynchronous Prep1-TiO2 Phosphopeptide enrichment, PartB Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen DUN1 KTR3 2 Unpublished Fields Lab Data
    View Screen YPT1 KTR3 2 Uetz P, et al. (2000)
    View Screen VAM7 KTR3 2 Uetz P, et al. (2000)
    View Screen YPT35 KTR3 2 Uetz P, et al. (2000)

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data KTR3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..404] Pfam 229.366532 Glycolipid 2-alpha-mannosyltransferase No confident structure predictions are available.
    2 View Details [75..404] PSI-BLAST 145.0 Crystal structure of yeast alpha1,2-mannosyltransferase Kre2p/Mnt1p

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • alpha-1,2-mannosyltransferase activity
    		•  6.0576932895264 bayes_pls_golite062009
  • mannosyltransferase activity
    		•  5.57855076532185 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  4.49413422196176 bayes_pls_golite062009
  • transferase activity, transferring glycosyl groups
    		•  4.37944217610823 bayes_pls_golite062009
  • UDP-glycosyltransferase activity
    		•  4.08451171179562 bayes_pls_golite062009
  • acetylgalactosaminyltransferase activity
    		•  3.4614674054855 bayes_pls_golite062009
  • transferase activity
    		•  3.32517438937547 bayes_pls_golite062009
  • polypeptide N-acetylgalactosaminyltransferase activity
    		•  3.19923094610567 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.51696952719873 bayes_pls_golite062009
  • catalytic activity
    		•  1.88676710996045 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  1.86990263440735 bayes_pls_golite062009
  • uridylyltransferase activity
    		•  1.27888067902271 bayes_pls_golite062009
  • binding
    		•  0.948692623641759 bayes_pls_golite062009
  • glucuronosyltransferase activity
    		•  0.36353543999278 bayes_pls_golite062009
  • protein binding
    		•  0.124656890356575 bayes_pls_golite062009
  • UDP-galactosyltransferase activity
    		•  0.10185872015123 bayes_pls_golite062009
  • galactosyltransferase activity
    		•  0.0931461042017721 bayes_pls_golite062009
  • acetylglucosaminyltransferase activity
    		•  0.0562130308868509 bayes_pls_golite062009
  • alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity
    		•  0.0339369954475406 bayes_pls_golite062009
  • intramolecular oxidoreductase activity
    		•  0.0122078907283503 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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    Created and Maintained by: Michael Riffle