Protein Overview: COX13

General Information:
Name(s) found:	COX13 / YGL191W [SGD]
Description(s) found: Found 34 descriptions. SHOW ALL	Subunit VIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; not essential for cytochrome c oxidase activity but may modulate activity in response to ATP [SGD]
Organism:	Saccharomyces cerevisiae
Length:	129 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA] mitochondrial respiratory chain complex IV [IPI]
Biological Process:	aerobic respiration [IMP]
Molecular Function:	cytochrome-c oxidase activity [IPI] enzyme regulator activity [IDA]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MFRQCAKRYA SSLPPNALKP AFGPPDKVAA QKFKESLMAT EKHAKDTSNM WVKISVWVAL 60 61 PAIALTAVNT YFVEKEHAEH REHLKHVPDS EWPRDYEFMN IRSKPFFWGD GDKTLFWNPV 120 121 VNRHIEHDD

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	(MIPS) Mewes HW, et al. (2004)		COX1 COX12 COX13 COX2 COX3 COX4 COX5A COX6 COX7 COX8 COX9
View Details	Qiu et al. (2008)		ATP14 ATP15 ATP2 ATP5 ATP6 ATP7 ATP8 COB COR1 COX1 COX13 COX2 COX3 COX4 COX5A COX5B COX6 COX7 COX8 COX9 CYT1 INH1 OLI1 QCR10 QCR2 QCR6 QCR7 QCR8 QCR9 RIP1 SDH2 SDH3 SDH4

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	ZDS1	Sample 3 - cpn + atp, from june 2005	McCusker D, et al (2007)

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

	BAIT	PREY	HITS	PUBLICATION
View Screen	NPA3	COX13	2	Unpublished Fields Lab Data

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No microscopy data found in the PDR for this protein.

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..129]	PSI-BLAST	100.38764	Mitochondrial cytochrome c oxidase subunit VIa

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
cytochrome-c oxidase activity	8.55593054200713	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors	8.55593054200713	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor	8.55593054200713	bayes_pls_golite062009
heme-copper terminal oxidase activity	8.33310447684473	bayes_pls_golite062009
oxidoreductase activity	4.93709142475202	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	3.42266067775966	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	3.27737232830687	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	2.64965096433631	bayes_pls_golite062009
cation transmembrane transporter activity	2.41719119401631	bayes_pls_golite062009
ion transmembrane transporter activity	2.22093703573522	bayes_pls_golite062009
catalytic activity	0.448769452796145	bayes_pls_golite062009

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.55