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Protein Overview: TPP1

General Information:
Name(s) found: TPP1 / YMR156C [SGD]
Description(s) found:
Found 30 descriptions.
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  • DNA 3'-phosphatase that functions in repair of endogenous damage of double-stranded DNA, activity is specific for removal of 3' phosphates at strand breaks; has similarity to the l-2-haloacid dehalogenase superfamily [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 238 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: DNA repair [IDALink to PubMed article][IMPLink to PubMed article]
    Molecular Function: polynucleotide 3'-phosphatase activity [IDALink to PubMed article][TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHKLTILPF LIKFTPKFPQ SIDHDEHGLN VYAFDLDHTI IKPKSPNISF SRSASDWQFI  60
   61 NFNSKKSTLD YLCNIIDNDP TAVIVIFSNQ GGVITVPRTS KSCTKYTNKI LLFLKAIKND 120
  121 ERGETLSHRL WLYAAPKRPK TFAANHSKIT FASLGESYNN DPNIFEKVRK PMTGMVEFFK 180
  181 RDLESAYRVS EQISPIKLNW IYYCGDAAGR KKDFSDSDIK FAENLHVEFK YPEEIFHG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen TPP1 ENP1 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..238] MSA 1.013974 View MSA. No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle