From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.054] [SVM Score: 0.597301811295] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
DNA polymerase complex | 2.2737E-6 | 2 | 10 | 2 | 6292 |
zeta DNA polymerase complex | 6.3568E-4 | 2 | 2 | 1 | 6292 |
epsilon DNA polymerase complex | 1.5888E-3 | 2 | 5 | 1 | 6292 |
nuclear replisome | 5.7138E-3 | 2 | 18 | 1 | 6292 |
replisome | 5.7138E-3 | 2 | 18 | 1 | 6292 |
nuclear replication fork | 6.3477E-3 | 2 | 20 | 1 | 6292 |
nucleotide-excision repair complex | 6.6645E-3 | 2 | 21 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
DNA repair | 9.2646E-4 | 2 | 192 | 2 | 6292 |
response to DNA damage stimulus | 1.4011E-3 | 2 | 236 | 2 | 6292 |
cellular response to stress | 2.1173E-3 | 2 | 290 | 2 | 6292 |
mutagenesis | 2.859E-3 | 2 | 9 | 1 | 6292 |
cellular response to stimulus | 3.6193E-3 | 2 | 379 | 2 | 6292 |
leading strand elongation | 4.7627E-3 | 2 | 15 | 1 | 6292 |
lagging strand elongation | 5.7138E-3 | 2 | 18 | 1 | 6292 |
response to stress | 6.2277E-3 | 2 | 497 | 2 | 6292 |
mismatch repair | 8.5646E-3 | 2 | 27 | 1 | 6292 |
DNA metabolic process | 8.631E-3 | 2 | 585 | 2 | 6292 |
DNA strand elongation | 9.8303E-3 | 2 | 31 | 1 | 6292 |
DNA strand elongation involved in DNA replication | 9.8303E-3 | 2 | 31 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
DNA-directed DNA polymerase activity | 3.0291E-4 | 2 | 110 | 2 | 6292 |
DNA polymerase activity | 3.312E-4 | 2 | 115 | 2 | 6292 |
nucleotidyltransferase activity | 7.0879E-4 | 2 | 168 | 2 | 6292 |
transferase activity, transferring phosphorus-containing groups | 4.4459E-3 | 2 | 420 | 2 | 6292 |
double-stranded DNA binding | 7.2981E-3 | 2 | 23 | 1 | 6292 |