From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.054] [SVM Score: 0.540056722259] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
spindle microtubule | 6.8716E-6 | 2 | 17 | 2 | 6292 |
microtubule | 2.3495E-5 | 2 | 31 | 2 | 6292 |
condensed nuclear chromosome kinetochore | 5.9419E-5 | 2 | 49 | 2 | 6292 |
condensed chromosome kinetochore | 5.9419E-5 | 2 | 49 | 2 | 6292 |
condensed chromosome, centromeric region | 7.5032E-5 | 2 | 55 | 2 | 6292 |
condensed nuclear chromosome, centromeric region | 7.5032E-5 | 2 | 55 | 2 | 6292 |
kinetochore | 8.9432E-5 | 2 | 60 | 2 | 6292 |
chromosome, centromeric region | 1.1171E-4 | 2 | 67 | 2 | 6292 |
condensed nuclear chromosome | 1.8468E-4 | 2 | 86 | 2 | 6292 |
spindle | 1.9786E-4 | 2 | 89 | 2 | 6292 |
condensed chromosome | 2.2085E-4 | 2 | 94 | 2 | 6292 |
microtubule cytoskeleton | 2.8118E-4 | 2 | 106 | 2 | 6292 |
nuclear chromosome part | 9.0721E-4 | 2 | 190 | 2 | 6292 |
cytoskeletal part | 1.0156E-3 | 2 | 201 | 2 | 6292 |
cytoskeleton | 1.1732E-3 | 2 | 216 | 2 | 6292 |
nuclear chromosome | 1.3075E-3 | 2 | 228 | 2 | 6292 |
chromosomal part | 1.413E-3 | 2 | 237 | 2 | 6292 |
chromosome | 1.8898E-3 | 2 | 274 | 2 | 6292 |
kinesin complex | 2.224E-3 | 2 | 7 | 1 | 6292 |
microtubule associated complex | 5.7138E-3 | 2 | 18 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
mitotic spindle organization in nucleus | 1.6421E-5 | 2 | 26 | 2 | 6292 |
mitotic spindle organization | 5.6994E-5 | 2 | 48 | 2 | 6292 |
spindle organization | 5.9419E-5 | 2 | 49 | 2 | 6292 |
microtubule cytoskeleton organization | 2.3525E-4 | 2 | 97 | 2 | 6292 |
microtubule-based process | 3.0847E-4 | 2 | 111 | 2 | 6292 |
cytoskeleton organization | 1.3422E-3 | 2 | 231 | 2 | 6292 |
mitotic cell cycle | 1.6363E-3 | 2 | 255 | 2 | 6292 |
mitotic anaphase B | 1.9064E-3 | 2 | 6 | 1 | 6292 |
M phase | 2.1762E-3 | 2 | 294 | 2 | 6292 |
anaphase | 2.224E-3 | 2 | 7 | 1 | 6292 |
mitotic anaphase | 2.224E-3 | 2 | 7 | 1 | 6292 |
cell cycle phase | 3.5621E-3 | 2 | 376 | 2 | 6292 |
cell cycle process | 6.0534E-3 | 2 | 490 | 2 | 6292 |
cell cycle | 6.95E-3 | 2 | 525 | 2 | 6292 |
microtubule nucleation | 7.2981E-3 | 2 | 23 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
microtubule binding | 3.1764E-3 | 2 | 10 | 1 | 6292 |
microtubule motor activity | 3.1764E-3 | 2 | 10 | 1 | 6292 |
motor activity | 5.7138E-3 | 2 | 18 | 1 | 6292 |
tubulin binding | 6.3477E-3 | 2 | 20 | 1 | 6292 |