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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.07] [SVM Score: 0.444257190101]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
HLJ1
  • endoplasmic reticulum membrane
  • endoplasmic reticulum
    		•
  • protein folding
  • ER-associated protein catabolic process
    		•
  • chaperone regulator activity
  • ATPase activator activity
    		•
    SEC23
  • cytoplasm
  • COPII vesicle coat
    		•
  • ER to Golgi vesicle-mediated transport
  • autophagy
  • ER-associated protein catabolic process
    		•
  • GTPase activator activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    COPII vesicle coat 2.5415E-3 2 8 1 6292
    ER to Golgi transport vesicle membrane 2.5415E-3 2 8 1 6292
    endomembrane system 3.9918E-3 2 398 2 6292
    transport vesicle membrane 4.7627E-3 2 15 1 6292
    ER to Golgi transport vesicle 9.8303E-3 2 31 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    ER-associated protein catabolic process 3.744E-5 2 39 2 6292
    proteasomal protein catabolic process 1.1854E-4 2 69 2 6292
    proteasomal ubiquitin-dependent protein catabolic process 1.1854E-4 2 69 2 6292
    modification-dependent protein catabolic process 6.1087E-4 2 156 2 6292
    ubiquitin-dependent protein catabolic process 6.1087E-4 2 156 2 6292
    proteolysis involved in cellular protein catabolic process 6.3467E-4 2 159 2 6292
    modification-dependent macromolecule catabolic process 6.7534E-4 2 164 2 6292
    cellular protein catabolic process 7.3441E-4 2 171 2 6292
    proteolysis 8.8816E-4 2 188 2 6292
    protein catabolic process 8.9766E-4 2 189 2 6292
    cellular macromolecule catabolic process 1.7674E-3 2 265 2 6292
    macromolecule catabolic process 2.1762E-3 2 294 2 6292
    cellular catabolic process 4.3405E-3 2 415 2 6292
    catabolic process 6.2027E-3 2 496 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    enzyme activator activity 1.1171E-4 2 67 2 6292
    nucleoside-triphosphatase regulator activity 2.256E-4 2 95 2 6292
    enzyme regulator activity 1.0773E-3 2 207 2 6292
    chaperone regulator activity 2.224E-3 2 7 1 6292
    ATPase activator activity 2.224E-3 2 7 1 6292
    ATPase regulator activity 3.4937E-3 2 11 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle