From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.945937543302] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
alpha DNA polymerase:primase complex | 1.0611E-6 | 2 | 7 | 2 | 6292 |
nuclear replisome | 7.7306E-6 | 2 | 18 | 2 | 6292 |
replisome | 7.7306E-6 | 2 | 18 | 2 | 6292 |
nuclear replication fork | 9.6001E-6 | 2 | 20 | 2 | 6292 |
replication fork | 4.3504E-5 | 2 | 42 | 2 | 6292 |
protein-DNA complex | 8.0641E-5 | 2 | 57 | 2 | 6292 |
nuclear chromosome part | 9.0721E-4 | 2 | 190 | 2 | 6292 |
nuclear chromosome | 1.3075E-3 | 2 | 228 | 2 | 6292 |
chromosomal part | 1.413E-3 | 2 | 237 | 2 | 6292 |
chromosome | 1.8898E-3 | 2 | 274 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
DNA synthesis involved in DNA repair | 3.0316E-7 | 2 | 4 | 2 | 6292 |
lagging strand elongation | 7.7306E-6 | 2 | 18 | 2 | 6292 |
DNA strand elongation | 2.3495E-5 | 2 | 31 | 2 | 6292 |
DNA strand elongation involved in DNA replication | 2.3495E-5 | 2 | 31 | 2 | 6292 |
DNA replication initiation | 2.6678E-5 | 2 | 33 | 2 | 6292 |
DNA-dependent DNA replication | 1.678E-4 | 2 | 82 | 2 | 6292 |
DNA replication | 3.791E-4 | 2 | 123 | 2 | 6292 |
DNA repair | 9.2646E-4 | 2 | 192 | 2 | 6292 |
response to DNA damage stimulus | 1.4011E-3 | 2 | 236 | 2 | 6292 |
DNA replication, synthesis of RNA primer | 1.5888E-3 | 2 | 5 | 1 | 6292 |
premeiotic DNA synthesis | 1.5888E-3 | 2 | 5 | 1 | 6292 |
cellular response to stress | 2.1173E-3 | 2 | 290 | 2 | 6292 |
cellular response to stimulus | 3.6193E-3 | 2 | 379 | 2 | 6292 |
response to stress | 6.2277E-3 | 2 | 497 | 2 | 6292 |
DNA metabolic process | 8.631E-3 | 2 | 585 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
DNA primase activity | 6.3568E-4 | 2 | 2 | 1 | 6292 |
nucleotidyltransferase activity | 7.0879E-4 | 2 | 168 | 2 | 6292 |
transferase activity, transferring phosphorus-containing groups | 4.4459E-3 | 2 | 420 | 2 | 6292 |