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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.036] [SVM Score: 0.812063287186]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

histone deacetylase complex 1.2783E-5 2 23 2 6292
chromatin remodeling complex 2.4511E-4 2 99 2 6292
Sin3 complex 1.2712E-3 2 4 1 6292
nucleoplasm part 1.5102E-3 2 245 2 6292
Sin3-type complex 1.5888E-3 2 5 1 6292
nucleoplasm 1.7541E-3 2 264 2 6292
nuclear lumen 5.1728E-3 2 453 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

chromatin silencing at rDNA 7.7306E-6 2 18 2 6292
histone deacetylation 1.7735E-5 2 27 2 6292
protein amino acid deacetylation 2.0514E-5 2 29 2 6292
chromatin silencing at silent mating-type cassette 2.6678E-5 2 33 2 6292
chromatin silencing at telomere 7.5032E-5 2 55 2 6292
covalent chromatin modification 1.9342E-4 2 88 2 6292
histone modification 1.9342E-4 2 88 2 6292
negative regulation of gene expression, epigenetic 2.5011E-4 2 100 2 6292
gene silencing 2.5011E-4 2 100 2 6292
regulation of gene expression, epigenetic 2.5011E-4 2 100 2 6292
chromatin silencing 2.5011E-4 2 100 2 6292
negative regulation of transcription, DNA-dependent 6.1875E-4 2 157 2 6292
negative regulation of RNA metabolic process 6.2668E-4 2 158 2 6292
negative regulation of transcription 6.7534E-4 2 164 2 6292
negative regulation of gene expression 6.7534E-4 2 164 2 6292
chromatin modification 7.0879E-4 2 168 2 6292
negative regulation of macromolecule biosynthetic process 7.6927E-4 2 175 2 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 8.1399E-4 2 180 2 6292
negative regulation of nitrogen compound metabolic process 8.1399E-4 2 180 2 6292
negative regulation of biosynthetic process 8.9766E-4 2 189 2 6292
negative regulation of cellular biosynthetic process 8.9766E-4 2 189 2 6292
negative regulation of macromolecule metabolic process 9.2646E-4 2 192 2 6292
chromatin organization 1.036E-3 2 203 2 6292
negative regulation of cellular metabolic process 1.0983E-3 2 209 2 6292
negative regulation of metabolic process 1.1088E-3 2 210 2 6292
negative regulation of cellular process 1.5726E-3 2 250 2 6292
negative regulation of biological process 1.6107E-3 2 253 2 6292
anatomical structure homeostasis 2.0592E-3 2 286 2 6292
telomere organization 2.0592E-3 2 286 2 6292
telomere maintenance 2.0592E-3 2 286 2 6292
post-translational protein modification 3.2108E-3 2 357 2 6292
regulation of transcription, DNA-dependent 3.2288E-3 2 358 2 6292
regulation of RNA metabolic process 3.3198E-3 2 363 2 6292
regulation of transcription 3.7155E-3 2 384 2 6292
homeostatic process 4.1951E-3 2 408 2 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.3405E-3 2 415 2 6292
regulation of nitrogen compound metabolic process 4.3615E-3 2 416 2 6292
regulation of gene expression 4.9915E-3 2 445 2 6292
regulation of macromolecule biosynthetic process 5.2416E-3 2 456 2 6292
regulation of cellular biosynthetic process 5.6164E-3 2 472 2 6292
regulation of biosynthetic process 5.6402E-3 2 473 2 6292
regulation of macromolecule metabolic process 6.004E-3 2 488 2 6292
protein modification process 6.278E-3 2 499 2 6292
transcription, DNA-dependent 6.3792E-3 2 503 2 6292
RNA biosynthetic process 6.5067E-3 2 508 2 6292
regulation of primary metabolic process 6.6615E-3 2 514 2 6292
regulation of cellular metabolic process 7.2445E-3 2 536 2 6292
regulation of metabolic process 7.5452E-3 2 547 2 6292
regulation of biological quality 7.6561E-3 2 551 2 6292
transcription 7.6839E-3 2 552 2 6292
chromosome organization 7.7677E-3 2 555 2 6292
double-strand break repair via nonhomologous end joining 7.9314E-3 2 25 1 6292
macromolecule modification 8.1649E-3 2 569 2 6292
DNA metabolic process 8.631E-3 2 585 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

histone deacetylase activity 2.5061E-5 2 32 2 6292
protein deacetylase activity 2.5061E-5 2 32 2 6292
deacetylase activity 3.0063E-5 2 35 2 6292
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 5.6994E-5 2 48 2 6292
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1.5966E-4 2 80 2 6292
transcription corepressor activity 5.0798E-3 2 16 1 6292
transcription coactivator activity 6.6645E-3 2 21 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle