YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. Catalysis of the reaction: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + NAD+ = 3-alpha,12-alpha-dihydroxy-7-oxo-5-beta-cholanate + NADH + H+. Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative. Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: 7-alpha-hydroxysteroid dehydrogenase activity
Acc: GO:0008709
Aspect: Molecular Function
Desc: Catalysis of the reaction: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + NAD+ = 3-alpha,12-alpha-dihydroxy-7-oxo-5-beta-cholanate + NADH + H+.
Synonyms:
  • 7alpha-hydroxysteroid:NAD+ 7-oxidoreductase activity
  • 7alpha-hydroxysteroid dehydrogenase activity
  • 7alpha-HSDH
  • 7alpha-hydroxy steroid dehydrogenase activity
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008709 - 7-alpha-hydroxysteroid dehydrogenase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle