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Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks. Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters. Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks. Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site. Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: Type II site-specific deoxyribonuclease activity
Acc: GO:0009036
Aspect: Molecular Function
Desc: Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.
Synonyms:
  • Type II restriction enzyme activity
Proteins in PDR annotated with:
   This term: 2 [Search]
   Term or descendants: 2 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0009036 - Type II site-specific deoxyribonuclease activity (interactive image map)

YRC Informatics Platform - Version 3.0
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