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The process whereby a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. The process whereby an activated receptor conveys information down the signaling pathway, resulting in a change in the function or state of a cell. The process whereby a signal is passed on from a receptor at the cell surface to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms. The process whereby a signal is passed from the insulin receptor to components of the phosphoinositide 3-kinase (PI3K) cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. The series of molecular events whereby information is sent from one location to another within a cell. The process whereby a signal is passed from the epidermal growth factor receptor (EGFR) to components of the MAPKKK cascade, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. The series of molecular signals that are initiated by the transmembrane protein Smoothened. In the presence of a Hedgehog signaling molecule, the Patched protein no longer inhibits the activity of Smoothened, and Smoothened signals via the Hedgehog signaling complex to activate downstream components of the Hedgehog signaling pathway. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: intracellular signal transduction involved in cell surface receptor linked signaling
Acc: GO:0035557
Aspect: Biological Process
Desc: The process whereby a signal is passed on from a receptor at the cell surface to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
Synonyms:
  • intracellular signaling cascade involved in cell surface receptor linked signaling
  • intracellular signaling chain involved in cell surface receptor signaling
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 6 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0035557 - intracellular signal transduction involved in cell surface receptor linked signaling (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle