YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|55670084, gi\|...
Organism:	Escherichia coli
Length:	255 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|55670084, gi|....

Description	E-value	Query Range	Subject Range
gi\|15602225, gi\|... - gi\|15602225\|ref\|NP_245297.1\| penicillin-insensitive murein endopeptidase [Pasteurella multocida subs...	394.0	[0..1]	[252..25]
MEPA_SALTY - Penicillin-insensitive murein endopeptidase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC ... gi\|204321765, gi... - gi\|204929221\|ref\|ZP_03220364.1\| penicillin-insensitive murein endopeptidase [Salmonella enterica sub... MEPA_SALG2 - Penicillin-insensitive murein endopeptidase OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN... MEPA_SALEP - Penicillin-insensitive murein endopeptidase OS=Salmonella enteritidis PT4 (strain P125109) GN=mepA P... MEPA_SALA4 - Penicillin-insensitive murein endopeptidase OS=Salmonella agona (strain SL483) GN=mepA PE=3 SV=1 gi\|197241281, gi... - gi\|197263026\|ref\|ZP_03163100.1\| penicillin-insensitive murein endopeptidase [Salmonella enterica sub... MEPA_SALDC - Penicillin-insensitive murein endopeptidase OS=Salmonella dublin (strain CT_02021853) GN=mepA PE=3 S... MEPA_SALTY - Penicillin-insensitive murein endopeptidase OS=Salmonella typhimurium GN=mepA PE=3 SV=1 gi\|200388495, gi... - gi\|200388495\|ref\|ZP_03215107.1\| penicillin-insensitive murein endopeptidase [Salmonella enterica sub... gi\|167993072, gi... - gi\|205328818\|gb\|EDZ15582.1\| penicillin-insensitive murein endopeptidase [Salmonella enterica subsp. ... gi\|168237408, gi... - gi\|197289596\|gb\|EDY28959.1\| penicillin-insensitive murein endopeptidase [Salmonella enterica subsp. ... MEPA_SALNS - Penicillin-insensitive murein endopeptidase OS=Salmonella newport (strain SL254) GN=mepA PE=3 SV=1 MEPA_SALSV - Penicillin-insensitive murein endopeptidase OS=Salmonella schwarzengrund (strain CVM19633) GN=mepA P... MEPA_SALTY - Penicillin-insensitive murein endopeptidase OS=Salmonella typhimurium GN=mepA PE=3 SV=1 lcl\|NC_016856.1_... - [gene=mepA] [protein=penicillin-insensitive murein endopeptidase] [protein_id=YP_005238467.1] [locat...	392.0	[0..1]	[255..20]
MEPA_SALTI - Penicillin-insensitive murein endopeptidase OS=Salmonella typhi GN=mepA PE=3 SV=1 gi\|238912338 - gi\|238912338\|ref\|ZP_04656175.1\| penicillin-insensitive murein endopeptidase [Salmonella enterica sub... gi\|16761307 - gi\|16761307\|ref\|NP_456924.1\| penicillin-insensitive murein endopeptidase [Salmonella enterica subsp.... gi\|213650418 - gi\|213650418\|ref\|ZP_03380471.1\| penicillin-insensitive murein endopeptidase [Salmonella enterica sub... gi\|213854940 - gi\|213854940\|ref\|ZP_03383180.1\| penicillin-insensitive murein endopeptidase [Salmonella enterica sub... MEPA_SALTI - Penicillin-insensitive murein endopeptidase OS=Salmonella typhi GN=mepA PE=3 SV=1 gi\|214001641 - gi\|214001641\|ref\|ZP_03412376.1\| penicillin-insensitive murein endopeptidase [Salmonella enterica sub... gi\|29140997, gi\|... - gi\|29140997\|ref\|NP_804339.1\| penicillin-insensitive murein endopeptidase [Salmonella enterica subsp.... gi\|205345118, gi... - gi\|205345118\|gb\|EDZ31882.1\| penicillin-insensitive murein endopeptidase [Salmonella enterica subsp. ... MEPA_SALPK - Penicillin-insensitive murein endopeptidase OS=Salmonella paratyphi A (strain AKU_12601) GN=mepA PE=... gi\|213161568 - gi\|213161568\|ref\|ZP_03347278.1\| penicillin-insensitive murein endopeptidase [Salmonella enterica sub... gi\|213612526 - gi\|213612526\|ref\|ZP_03370352.1\| penicillin-insensitive murein endopeptidase [Salmonella enterica sub...	392.0	[0..1]	[255..20]
MEPA_SALCH - Penicillin-insensitive murein endopeptidase OS=Salmonella choleraesuis (strain SC-B67) GN=mepA PE=3 ... MEPA_SALCH - Penicillin-insensitive murein endopeptidase OS=Salmonella choleraesuis GN=mepA PE=3 SV=1 MEPA_SALCH - Penicillin-insensitive murein endopeptidase OS=Salmonella choleraesuis GN=mepA PE=3 SV=1	389.0	[0..1]	[255..20]
MEPA_SALPA - Penicillin-insensitive murein endopeptidase OS=Salmonella paratyphi A GN=mepA PE=3 SV=1 MEPA_SALPA - Penicillin-insensitive murein endopeptidase OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN...	388.0	[0..1]	[255..20]
MEPA_ECOL5 - Penicillin-insensitive murein endopeptidase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=me... gi\|75243139, gi\|... - gi\|75243139\|ref\|ZP_00726845.1\| COG3770: Murein endopeptidase [Escherichia coli F11], gi\|191170090\|re...	388.0	[0..2]	[255..21]
MEPA_ECOL6 - Penicillin-insensitive murein endopeptidase OS=Escherichia coli O6 GN=mepA PE=3 SV=1 MEPA_ECO27 - Penicillin-insensitive murein endopeptidase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=... sp\|B7UFY6\|MEPA_ECO27 - Penicillin-insensitive murein endopeptidase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=... MEPA_ECO45 - Penicillin-insensitive murein endopeptidase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=mepA ... MEPA_ECO81 - Penicillin-insensitive murein endopeptidase OS=Escherichia coli O81 (strain ED1a) GN=mepA PE=3 SV=1 MEPA_ECO7I - Penicillin-insensitive murein endopeptidase OS=Escherichia coli O7:K1 (strain IAI39 / ExPEC) GN=mepA... MEPA_ECOSM - Penicillin-insensitive murein endopeptidase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=mepA PE=... MEPA_ECOUT - Penicillin-insensitive murein endopeptidase OS=Escherichia coli (strain UTI89 / UPEC) GN=mepA PE=3 S... MEPA_ECOK1 - Penicillin-insensitive murein endopeptidase OS=Escherichia coli O1:K1 / APEC GN=mepA PE=3 SV=1 gi\|237704808, gi... - gi\|237704808\|ref\|ZP_04535289.1\| penicillin-insensitive Murein endopeptidase [Escherichia sp. 3_2_53F... MEPA_ECOL6 - Penicillin-insensitive murein endopeptidase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 /... gi\|227835738, gi... - gi\|227887388\|ref\|ZP_04005193.1\| penicillin-insensitive murein endopeptidase [Escherichia coli 83972]...	388.0	[0..2]	[255..21]
MEPA_SHIFL - Penicillin-insensitive murein endopeptidase OS=Shigella flexneri GN=mepA PE=3 SV=1 gi\|89109148, gi\|... - gi\|89109148\|ref\|AP_002928.1\| murein DD-endopeptidase [Escherichia coli str. K-12 substr. W3110], gi\|... gi\|24052769, gi\|... - gi\|24113700\|ref\|NP_708210.1\| penicillin-insensitive murein endopeptidase [Shigella flexneri 2a str. ... MEPA_SHIF8 - Penicillin-insensitive murein endopeptidase OS=Shigella flexneri serotype 5b (strain 8401) GN=mepA P... MEPA_ECOLI - Penicillin-insensitive murein endopeptidase precursor (EC 3.4.24.-) (D-alanyl-D-alanine-endopeptidas... gi\|30063754, gi\|... - gi\|30063754\|ref\|NP_837925.1\| penicillin-insensitive murein endopeptidase [Shigella flexneri 2a str. ... EG10580 - murein DD-endopeptidase / Murein DD-endopeptidase, penicillin-insensitive EG10580 - murein DD-endopeptidase / Murein DD-endopeptidase, penicillin-insensitive MEPA_ECODH - Penicillin-insensitive murein endopeptidase OS=Escherichia coli (strain K12 / DH10B) GN=mepA PE=3 SV... gi\|194436067, gi... - gi\|83588352\|ref\|ZP_00926977.1\| COG3770: Murein endopeptidase [Escherichia coli 101-1], gi\|194436067\|... MEPA_ECOBW - Penicillin-insensitive murein endopeptidase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=me...	388.0	[0..2]	[255..21]
gi\|209764704, gi... - gi\|209764704\|gb\|ACI80664.1\| murein DD-endopeptidase [Escherichia coli], gi\|209764698\|gb\|ACI80661.1\| ... MEPA_SHIDS - Penicillin-insensitive murein endopeptidase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=mep...	388.0	[0..2]	[255..21]
MEPA_ECOLC - Penicillin-insensitive murein endopeptidase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crook... gi\|188490338, gi... - gi\|75515693\|ref\|ZP_00737828.1\| COG3770: Murein endopeptidase [Escherichia coli 53638], gi\|188495139\|... MEPA_ECO24 - Penicillin-insensitive murein endopeptidase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=... gi\|124526493, gi... - gi\|124526493\|ref\|ZP_01698446.1\| peptidase U6, penicillin-insensitive murein endopeptidase [Escherich... MEPA_ECO8A - Penicillin-insensitive murein endopeptidase OS=Escherichia coli O8 (strain IAI1) GN=mepA PE=3 SV=1	388.0	[0..2]	[255..21]

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Predicted Domain #1

Region A:
Residues: [1-255]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ATPWQKITQP VPGSAQSIGS FSNGCIVGAD TLPIQSEHYQ VMRTDQRRYF GHPDLVMFIQ  60
   61 RLSSQVSNLG MGTVLIGDMG MPAGGRFNGG HASHQTGLDV DIFLQLPKTR WTSAQLLRPQ 120
  121 ALDLVSRDGK HVVSTLWKPE IFSLIKLAAQ DKDVTRIFVN PAIKQQLCLD AGTDRDWLRK 180
  181 VRPWFQHRAH MHVRLRCPAD SLECEDQPLP PSGDGCGAEL QSWFEPPKPG TTKPEKKTPP 240
  241 PLPPSCQALL DEHVI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	109.0
Match:	1tzpA
Description:	MEPA, inactive form without ZN in P21
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.579809417316389	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: