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View Structure Prediction Details

Protein: gi|42566965
Organism: Arabidopsis thaliana
Length: 859 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|42566965.

Description E-value Query
Range
Subject
Range
AKH2_ARATH - Bifunctional aspartokinase/homoserine dehydrogenase 2, chloroplastic OS=Arabidopsis thaliana GN=AKHS...
819.0 [0..1] [856..1]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATLKPSFTV SPPNSNPIRF GSFPPQCFLR VPKPRRLILP RFRKTTGGGG GLIRCELPDF  60
   61 HLSATATTVS GVSTVNLVDQ VQIPKG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [87-554]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EMWSVHKFGG TCVGNSQRIR NVAEVIINDN SERKLVVVSA MSKVTDMMYD LIRKAQSRDD  60
   61 SYLSALEAVL EKHRLTARDL LDGDDLASFL SHLHNDISNL KAMLRAIYIA GHASESFSDF 120
  121 VAGHGELWSA QMLSYVVRKT GLECKWMDTR DVLIVNPTSS NQVDPDFGES EKRLDKWFSL 180
  181 NPSKIIIATG FIASTPQNIP TTLKRDGSDF SAAIMGALLR ARQVTIWTDV DGVYSADPRK 240
  241 VNEAVILQTL SYQEAWEMSY FGANVLHPRT IIPVMRYNIP IVIRNIFNLS APGTIICQPP 300
  301 EDDYDLKLTT PVKGFATIDN LALINVEGTG MAGVPGTASD IFGCVKDVGA NVIMISQASS 360
  361 EHSVCFAVPE KEVNAVSEAL RSRFSEALQA GRLSQIEVIP NCSILAAVGQ KMASTPGVSC 420
  421 TLFSALAKAN INVRAISQGC SEYNVTVVIK REDSVKALRA VHSRFFLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 97.522879
Match: 2hmfA
Description: No description for 2hmfA was found.

Predicted functions:

Term Confidence Notes
acetolactate synthase activity 3.48670706716817 bayes_pls_golite062009
aspartate kinase activity 3.23731032633773 bayes_pls_golite062009
kinase activity 2.6815187488202 bayes_pls_golite062009
phosphotransferase activity, carboxyl group as acceptor 2.65970393362911 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 2.63366715780289 bayes_pls_golite062009
amino acid kinase activity 2.38310367076654 bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups 2.27460110663386 bayes_pls_golite062009
acetylglutamate kinase activity 1.28891782911186 bayes_pls_golite062009
catalytic activity 0.645256181736122 bayes_pls_golite062009
transferase activity 0.576589833246962 bayes_pls_golite062009
binding 0.532494654284107 bayes_pls_golite062009
glutamate 5-kinase activity 0.416864856459166 bayes_pls_golite062009
protein binding 0.066675161728882 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [555-859]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RTTLAMGIVG PGLIGATLLD QLRDQAAVLK QEFNIDLRVL GITGSKKMLL SDIGIDLSRW  60
   61 RELLNEKGTE ADLDKFTQQV HGNHFIPNSV VVDCTADSAI ASRYYDWLRK GIHVITPNKK 120
  121 ANSGPLDQYL KLRDLQRKSY THYFYEATVG AGLPIISTLR GLLETGDKIL RIEGICSGTL 180
  181 SYLFNNFVGD RSFSEVVTEA KNAGFTEPDP RDDLSGTDVA RKVIILARES GLKLDLADLP 240
  241 IRSLVPEPLK GCTSVEEFME KLPQYDGDLA KERLDAENSG EVRLFTTNVF PFDQCDHILT 300
  301 IYICM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 66.221849
Match: 1q7gA
Description: Homoserine Dehydrogenase in complex with suicide inhibitor complex NAD-5-hydroxy-4-Oxonorvaline
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity 2.60548927745815 bayes_pls_golite062009
catalytic activity 2.54843319568228 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors 1.54909195188343 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 0.841370849960815 bayes_pls_golite062009
phosphoglycerate dehydrogenase activity 0.639509916626856 bayes_pls_golite062009
saccharopine dehydrogenase activity 0.495113665163626 bayes_pls_golite062009
N-acetyl-gamma-glutamyl-phosphate reductase activity 0.0651785123513661 bayes_pls_golite062009
binding 0.0273599514394109 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle