YRC Public Data Repository - Protein Structure Prediction

Protein:	GNTK_ECOLI
Organism:	Escherichia coli
Length:	175 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GNTK_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|110616819, gi... - gi\|110807271\|ref\|YP_690791.1\| gluconate kinase 1 [Shigella flexneri 5 str. 8401], gi\|110616819\|gb\|AB... gi\|161485823 - gi\|161485823\|ref\|NP_709212.3\| gluconate kinase 1 [Shigella flexneri 2a str. 301] gi\|161486383 - gi\|161486383\|ref\|NP_839451.2\| gluconate kinase 1 [Shigella flexneri 2a str. 2457T]	152.0	[0..1]	[175..1]
gi\|56962388, gi\|... - gi\|56962388\|ref\|YP_174114.1\| adenylylsulfate kinase [Bacillus clausii KSM-K16], gi\|56908626\|dbj\|BAD6...	152.0	[0..4]	[174..24]
gi\|50746429 - gi\|50746429\|ref\|XP_420493.1\| PREDICTED: similar to Bifunctional 3-phosphoadenosine 5-phosphosulfate ...	149.0	[0..7]	[174..424]
gi\|29139884, gi\|... - gi\|29144247\|ref\|NP_807589.1\| gluconate kinase 1 [Salmonella enterica subsp. enterica serovar Typhi s... gi\|16762760 - gi\|16762760\|ref\|NP_458377.1\| gluconate kinase 1 [Salmonella enterica subsp. enterica serovar Typhi s... gi\|16505066, gi\|... - gi\|25322008\|pir\|\|AC0995 probable gluconokinase (EC 2.7.1.12) [imported] - Salmonella enterica subsp.... gi\|16766828, gi\|... - gi\|16766828\|ref\|NP_462443.1\| gluconate kinase 1 [Salmonella typhimurium LT2], gi\|16422101\|gb\|AAL2240... gi\|213650005 - gi\|213650005\|ref\|ZP_03380058.1\| gluconate kinase 1 [Salmonella enterica subsp. enterica serovar Typh... gi\|224469862, gi... - gi\|224585334\|ref\|YP_002639133.1\| putative gluconokinase [Salmonella enterica subsp. enterica serovar... gi\|162139532 - gi\|162139532\|ref\|YP_218459.2\| gluconate kinase 1 [Salmonella enterica subsp. enterica serovar Choler... gi\|197364373, gi... - gi\|197364373\|ref\|YP_002144010.1\| gluconate kinase 1 [Salmonella enterica subsp. enterica serovar Par... gi\|213426860 - gi\|213426860\|ref\|ZP_03359610.1\| gluconate kinase 1 [Salmonella enterica subsp. enterica serovar Typh... lcl\|NC_016856.1_... - [gene=gntK] [protein=gluconate kinase] [protein_id=YP_005239749.1] [location=complement(3725194..372... gi\|213613279 - gi\|213613279\|ref\|ZP_03371105.1\| gluconate kinase 1 [Salmonella enterica subsp. enterica serovar Typh... gi\|56415443, gi\|... - gi\|56415443\|ref\|YP_152518.1\| gluconate kinase 1 [Salmonella enterica subsp. enterica serovar Paratyp... gi\|161616582, gi... - gi\|161616582\|ref\|YP_001590547.1\| gluconate kinase 1 [Salmonella enterica subsp. enterica serovar Par...	149.0	[0..1]	[173..1]
gi\|74002087 - gi\|74002087\|ref\|XP_863076.1\| PREDICTED: similar to Bifunctional 3-phosphoadenosine 5-phosphosulfate ...	149.0	[0..7]	[175..52]
gi\|91074493, gi\|... - gi\|91212919\|ref\|YP_542905.1\| gluconate kinase 1 [Escherichia coli UTI89], gi\|91074493\|gb\|ABE09374.1\|... gi\|190908238, gi... - gi\|191171611\|ref\|ZP_03033159.1\| thermoresistant gluconokinase [Escherichia coli F11], gi\|190908238\|g...	148.0	[0..1]	[175..8]
CYSC_MARHV - Adenylyl-sulfate kinase OS=Marinobacter hydrocarbonoclasticus (strain ATCC 700491 / DSM 11845 / VT8)...	148.0	[0..3]	[175..19]
gi\|110284175, gi... - gi\|69280172\|ref\|ZP_00614844.1\| Adenylylsulfate kinase [Mesorhizobium sp. BNC1], gi\|68189596\|gb\|EAN04...	148.0	[0..2]	[174..462]
CYSC_CLOAB - Adenylyl-sulfate kinase OS=Clostridium acetobutylicum GN=cysC PE=3 SV=1 CYSC_CLOAB - Adenylyl-sulfate kinase OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 57...	148.0	[0..6]	[175..27]

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Predicted Domain #1

Region A:
Residues: [1-175]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTTNHDHHI YVLMGVSGSG KSAVASEVAH QLHAAFLDGD FLHPRRNIEK MASGEPLNDD  60
   61 DRKPWLQALN DAAFAMQRTN KVSLIVCSAL KKHYRDLLRE GNPNLSFIYL KGDFDVIESR 120
  121 LKARKGHFFK TQMLVTQFET LQEPGADETD VLVVDIDQPL EGVVASTIEV IKKGK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.0
Match:	1knqA
Description:	Gluconate kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.00104173493322	bayes_pls_golite062009
nucleic acid binding	0.277920206084984	bayes_pls_golite062009
binding	0.100582610715958	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: