YRC Public Data Repository - Protein Structure Prediction

Protein:	NUDK_ERWCT
Organism:	Pectobacterium atrosepticum
Length:	193 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUDK_ERWCT.

Description	E-value	Query Range	Subject Range
gi\|238728697, gi... - gi\|77977001\|ref\|ZP_00832463.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ...	172.0	[0..1]	[190..11]
gi\|238799355, gi... - gi\|77960884\|ref\|ZP_00824738.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ...	172.0	[0..1]	[190..1]
gi\|238783884, gi... - gi\|77959004\|ref\|ZP_00823029.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ...	171.0	[0..1]	[190..1]
gi\|77974596, gi\|... - gi\|77974596\|ref\|ZP_00830135.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ...	160.0	[0..1]	[190..1]
gi\|110279325, gi... - gi\|110636644\|ref\|YP_676851.1\| hypothetical protein CHU_0219 [Cytophaga hutchinsonii ATCC 33406], gi\|... gi\|48855667 - gi\|48855667\|ref\|ZP_00309825.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ...	157.0	[0..1]	[189..1]
gi\|88709484, gi\|... - gi\|88712078\|ref\|ZP_01106165.1\| hypothetical protein FB2170_14353 [Flavobacteriales bacterium HTCC217...	152.0	[0..4]	[190..18]
gi\|22125345, gi\|... - gi\|22125345\|ref\|NP_668768.1\| hypothetical protein y1448 [Yersinia pestis KIM], gi\|21958226\|gb\|AAM850... gi\|145211110, gi... - gi\|145599414\|ref\|YP_001163490.1\| hypothetical protein YPDSF_2140 [Yersinia pestis Pestoides F], gi\|1... gi\|108775161, gi... - gi\|108811513\|ref\|YP_647280.1\| hypothetical protein YPN_1350 [Yersinia pestis Nepal516], gi\|108775161... gi\|77633176 - gi\|77633176\|ref\|ZP_00795322.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ... gi\|117672973, gi... - gi\|77629801\|ref\|ZP_00792387.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ... gi\|167467005 - gi\|167467005\|ref\|ZP_02331709.1\| hypothetical protein YpesF_03705 [Yersinia pestis FV-1] gi\|89104824 - gi\|89104824\|ref\|ZP_01177356.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ... Q668I3\|Q668I3_YERPS - Putative uncharacterized protein - Yersinia pseudotuberculosis gi\|51597073, gi\|... - gi\|51597073\|ref\|YP_071264.1\| hypothetical protein YPTB2757 [Yersinia pseudotuberculosis IP 32953], g...	150.0	[0..1]	[187..10]
gi\|166206543, gi... - gi\|166212612\|ref\|ZP_02238647.1\| hydrolase, NUDIX family [Yersinia pestis biovar Antiqua str. B420030... gi\|167422712, gi... - gi\|167422712\|ref\|ZP_02314465.1\| hydrolase, NUDIX family [Yersinia pestis biovar Orientalis str. MG05... gi\|167056360, gi... - gi\|167424478\|ref\|ZP_02316231.1\| hydrolase, NUDIX family [Yersinia pestis biovar Mediaevalis str. K19... gi\|186699188, gi... - gi\|186896162\|ref\|YP_001873274.1\| NUDIX hydrolase [Yersinia pseudotuberculosis PB1/+], gi\|186699188\|g... gi\|162354342, gi... - gi\|162421527\|ref\|YP_001607177.1\| NUDIX family hydrolase [Yersinia pestis Angola], gi\|162354342\|gb\|AB... gi\|165921272, gi... - gi\|165926921\|ref\|ZP_02222753.1\| hydrolase, NUDIX family [Yersinia pestis biovar Orientalis str. F199... gi\|45437299, gi\|... - gi\|45442434\|ref\|NP_993973.1\| NTP pyrophosphohydrolase including oxidative damage repair enzyme [Yers... gi\|165935854, gi... - gi\|165935854\|ref\|ZP_02224424.1\| hydrolase, NUDIX family [Yersinia pestis biovar Orientalis str. IP27... NUDK_YERPE - GDP-mannose pyrophosphatase NudK OS=Yersinia pestis GN=nudK PE=3 SV=1 gi\|165989943, gi... - gi\|166011265\|ref\|ZP_02232163.1\| hydrolase, NUDIX family [Yersinia pestis biovar Antiqua str. E197900... gi\|218930080, gi... - gi\|218930080\|ref\|YP_002347955.1\| hypothetical protein YPO3035 [Yersinia pestis CO92], gi\|16123212\|re... NUDK_YERP3 - GDP-mannose pyrophosphatase NudK OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=n... gi\|149291517, gi... - gi\|149365104\|ref\|ZP_01887139.1\| hypothetical protein YPE_0240 [Yersinia pestis CA88-4125], gi\|149291... gi\|229701502, gi... - gi\|229895696\|ref\|ZP_04510867.1\| Nudix hydrolase family protein YffH [Yersinia pestis Pestoides A], g... gi\|229899196, gi... - gi\|229899196\|ref\|ZP_04514339.1\| Nudix hydrolase family protein YffH [Yersinia pestis biovar Oriental... gi\|229694996, gi... - gi\|229838630\|ref\|ZP_04458789.1\| Nudix hydrolase family protein YffH [Yersinia pestis biovar Oriental... NUDK_YERPY - GDP-mannose pyrophosphatase NudK OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=nudK ... NUDK_YERPS - GDP-mannose pyrophosphatase NudK OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=nudK ... NUDK_YERPS - GDP-mannose pyrophosphatase nudK OS=Yersinia pseudotuberculosis GN=nudK PE=3 SV=2 NUDK_YERPP - GDP-mannose pyrophosphatase NudK OS=Yersinia pestis (strain Pestoides F) GN=nudK PE=3 SV=2 NUDK_YERPN - GDP-mannose pyrophosphatase NudK OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=nudK PE=3 SV=2	150.0	[0..1]	[187..1]
gi\|194437586, gi... - gi\|83586885\|ref\|ZP_00925516.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ...	149.0	[0..1]	[189..1]
gi\|254593811, gi... - gi\|254794411\|ref\|YP_003079248.1\| GDP-mannose pyrophosphatase [Escherichia coli O157:H7 str. TW14359]... NUDK_ECO57 - GDP-mannose pyrophosphatase NudK OS=Escherichia coli O157:H7 GN=nudK PE=3 SV=1 gi\|217327582, gi... - gi\|217327582\|ref\|ZP_03443665.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. TW14588], gi\|... gi\|209763816, gi... - pir\|\|D85889 hypothetical protein yffH [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|15802989, gi\|... - gi\|15802989\|ref\|NP_289019.1\| hypothetical protein Z3723 [Escherichia coli O157:H7 EDL933], gi\|125168... gi\|208726784, gi... - gi\|208806983\|ref\|ZP_03249320.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4206], gi\|2... NUDK_SHIDS - GDP-mannose pyrophosphatase NudK OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=nudK PE=3 SV=1 gi\|208812164, gi... - gi\|208812164\|ref\|ZP_03253493.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4045], gi\|2... gi\|208739916, gi... - gi\|208819793\|ref\|ZP_03260113.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4042], gi\|2... gi\|209161144, gi... - gi\|209399744\|ref\|YP_002271935.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4115], gi\|... gi\|189003249, gi... - gi\|189003249\|gb\|EDU72235.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4076], gi\|16877... gi\|168787805, gi... - gi\|189372369\|gb\|EDU90785.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC869], gi\|168787... gi\|189378674, gi... - gi\|189378674\|gb\|EDU97090.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC508], gi\|168798... gi\|195936608 - gi\|195936608\|ref\|ZP_03081990.1\| hypothetical protein EscherichcoliO157_09130 [Escherichia coli O157:... gi\|189356578, gi... - gi\|189356578\|gb\|EDU74997.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4401], gi\|16875... gi\|168761068, gi... - gi\|189368367\|gb\|EDU86783.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4501], gi\|16876... gi\|168768551, gi... - gi\|189362205\|gb\|EDU80624.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4486], gi\|16876... gi\|187770616, gi... - gi\|187770616\|gb\|EDU34460.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4196], gi\|16877... gi\|15832583, gi\|... - gi\|15832583\|ref\|NP_311356.1\| hypothetical protein ECs3329 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|188017097, gi... - gi\|188017097\|gb\|EDU55219.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4113], gi\|16874...	149.0	[0..1]	[190..1]

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Predicted Domain #1

Region A:
Residues: [1-193]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSPIDIVEK KLLSDHWFIL HKYVFDLKRK NGGVVRQIRE VYDRGDGATI LLYNRAKGTV  60
   61 ILTRQFRIPT YVNGNESGML LEACAGLLDD YSPEECIRNE AIEETGYAVG NVEKLFDAYM 120
  121 SPGGVTERLH FFAAEYDESL RDNSGGGVED EDIEVLELPF SEAIAMMNDG RIKDGKTIML 180
  181 LQHAIIRGWF AKG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.09691
Match:	1viuA
Description:	Crystal structure of putative ADP ribose pyrophosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.49075808737475	bayes_pls_golite062009
hydrolase activity	1.0879699007552	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.859040726089354	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.859001295204634	bayes_pls_golite062009
pyrophosphatase activity	0.231401568856773	bayes_pls_golite062009
binding	0.165092558977235	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: