YRC Public Data Repository - Protein Structure Prediction

Protein:	NUDK_SHIFL
Organism:	Shigella flexneri
Length:	191 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUDK_SHIFL.

Description	E-value	Query Range	Subject Range
gi\|238783884, gi... - gi\|77959004\|ref\|ZP_00823029.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ...	162.0	[0..1]	[190..1]
gi\|238799355, gi... - gi\|77960884\|ref\|ZP_00824738.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ...	160.0	[0..1]	[190..1]
gi\|26109242, gi\|... - gi\|26248836\|ref\|NP_754876.1\| hypothetical protein c2994 [Escherichia coli CFT073], gi\|26109242\|gb\|AA... gi\|237704981, gi... - gi\|237704981\|ref\|ZP_04535462.1\| GDP-mannose pyrophosphatase nudK [Escherichia sp. 3_2_53FAA], gi\|226... gi\|91073372, gi\|... - gi\|91211798\|ref\|YP_541784.1\| hypothetical protein UTI89_C2793 [Escherichia coli UTI89], gi\|91073372\|...	157.0	[0..1]	[191..10]
gi\|254593811, gi... - gi\|254794411\|ref\|YP_003079248.1\| GDP-mannose pyrophosphatase [Escherichia coli O157:H7 str. TW14359]... NUDK_ECO57 - GDP-mannose pyrophosphatase NudK OS=Escherichia coli O157:H7 GN=nudK PE=3 SV=1 gi\|217327582, gi... - gi\|217327582\|ref\|ZP_03443665.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. TW14588], gi\|... gi\|209763816, gi... - pir\|\|D85889 hypothetical protein yffH [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|15802989, gi\|... - gi\|15802989\|ref\|NP_289019.1\| hypothetical protein Z3723 [Escherichia coli O157:H7 EDL933], gi\|125168... gi\|208726784, gi... - gi\|208806983\|ref\|ZP_03249320.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4206], gi\|2... NUDK_SHIDS - GDP-mannose pyrophosphatase NudK OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=nudK PE=3 SV=1 gi\|208812164, gi... - gi\|208812164\|ref\|ZP_03253493.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4045], gi\|2... gi\|208739916, gi... - gi\|208819793\|ref\|ZP_03260113.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4042], gi\|2... gi\|209161144, gi... - gi\|209399744\|ref\|YP_002271935.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4115], gi\|... gi\|189003249, gi... - gi\|189003249\|gb\|EDU72235.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4076], gi\|16877... gi\|168787805, gi... - gi\|189372369\|gb\|EDU90785.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC869], gi\|168787... gi\|189378674, gi... - gi\|189378674\|gb\|EDU97090.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC508], gi\|168798... gi\|195936608 - gi\|195936608\|ref\|ZP_03081990.1\| hypothetical protein EscherichcoliO157_09130 [Escherichia coli O157:... gi\|189356578, gi... - gi\|189356578\|gb\|EDU74997.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4401], gi\|16875... gi\|168761068, gi... - gi\|189368367\|gb\|EDU86783.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4501], gi\|16876... gi\|168768551, gi... - gi\|189362205\|gb\|EDU80624.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4486], gi\|16876... gi\|187770616, gi... - gi\|187770616\|gb\|EDU34460.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4196], gi\|16877... gi\|15832583, gi\|... - gi\|15832583\|ref\|NP_311356.1\| hypothetical protein ECs3329 [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|188017097, gi... - gi\|188017097\|gb\|EDU55219.1\| hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4113], gi\|16874...	156.0	[0..1]	[191..1]
YFFH_ECOLI - Putative hydrolase yffH (EC 3.1.-.-) - Escherichia coli EG12410 - GDP-mannose pyrophosphatase / GDP-mannose pyrophosphatase gi\|124499639, gi... - gi\|124529779\|ref\|ZP_01700656.1\| NUDIX hydrolase [Escherichia coli B], gi\|124499639\|gb\|EAY47124.1\| NU... EG12410 - GDP-mannose pyrophosphatase / GDP-mannose pyrophosphatase NUDK_ECOLC - GDP-mannose pyrophosphatase NudK OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=nudK ... NUDK_ECODH - GDP-mannose pyrophosphatase NudK OS=Escherichia coli (strain K12 / DH10B) GN=nudK PE=3 SV=1 gi\|188495489, gi... - gi\|75515805\|ref\|ZP_00737940.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ... NUDK_ECOHS - GDP-mannose pyrophosphatase NudK OS=Escherichia coli O9:H4 (strain HS) GN=nudK PE=3 SV=1 gi\|89109272, gi\|... - gi\|89109272\|ref\|AP_003052.1\| predicted NUDIX hydrolase [Escherichia coli str. K-12 substr. W3110], g... gi\|238901630, gi... - gi\|238901630\|ref\|YP_002927426.1\| putative NUDIX hydrolase [Escherichia coli BW2952], gi\|238862699\|gb... gi\|242378066, gi... - gi\|251785793\|ref\|YP_003000097.1\| hypothetical protein B21_02320 [Escherichia coli BL21], gi\|24237806... gi\|253978509, gi... - gi\|254289202\|ref\|YP_003054950.1\| predicted NUDIX hydrolase [Escherichia coli BL21(DE3)], gi\|25397850... gi\|253974342, gi... - gi\|254162441\|ref\|YP_003045549.1\| predicted NUDIX hydrolase [Escherichia coli B str. REL606], gi\|2539...	156.0	[0..1]	[191..1]
gi\|238728697, gi... - gi\|77977001\|ref\|ZP_00832463.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ...	156.0	[0..1]	[187..11]
NUDK_ECOL5 - GDP-mannose pyrophosphatase NudK OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=nudK PE=3 SV=... gi\|218690593, gi... - gi\|218690593\|ref\|YP_002398805.1\| putative NUDIX hydrolase [Escherichia coli ED1a], gi\|218428157\|emb\|... gi\|227835853, gi... - gi\|227887503\|ref\|ZP_04005308.1\| possible ADP-ribose diphosphatase [Escherichia coli 83972], gi\|22783... NUDK_ECOK1 - GDP-mannose pyrophosphatase NudK OS=Escherichia coli O1:K1 / APEC GN=nudK PE=3 SV=1 NUDK_ECOUT - GDP-mannose pyrophosphatase NudK OS=Escherichia coli (strain UTI89 / UPEC) GN=nudK PE=3 SV=2 NUDK_ECOL6 - GDP-mannose pyrophosphatase NudK OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=n... NUDK_ECOL6 - GDP-mannose pyrophosphatase nudK OS=Escherichia coli O6 GN=nudK PE=3 SV=2 gi\|215265840, gi... - gi\|215487768\|ref\|YP_002330199.1\| predicted NUDIX hydrolase [Escherichia coli O127:H6 str. E2348/69],... gi\|191172915, gi... - gi\|75240116\|ref\|ZP_00724075.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ... gi\|218366171, gi... - gi\|218559402\|ref\|YP_002392315.1\| putative NUDIX hydrolase [Escherichia coli S88], gi\|218366171\|emb\|C...	155.0	[0..1]	[191..1]
gi\|209913198, gi... - gi\|209919939\|ref\|YP_002294023.1\| hypothetical protein ECSE_2748 [Escherichia coli SE11], gi\|20991319... gi\|193064738, gi... - gi\|75257270\|ref\|ZP_00728794.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ... gi\|192958306, gi... - gi\|75237790\|ref\|ZP_00721806.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ... gi\|194427327, gi... - gi\|75211428\|ref\|ZP_00711518.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ...	155.0	[0..1]	[191..1]
gi\|75178062, gi\|... - gi\|75178062\|ref\|ZP_00698121.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ... gi\|218696093, gi... - gi\|218696093\|ref\|YP_002403760.1\| putative NUDIX hydrolase [Escherichia coli 55989], gi\|218352825\|emb... NUDK_ECO24 - GDP-mannose pyrophosphatase NudK OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=nudK PE=3 S... gi\|218433062, gi... - gi\|218705965\|ref\|YP_002413484.1\| putative NUDIX hydrolase [Escherichia coli UMN026], gi\|218433062\|em... gi\|218554990, gi... - gi\|218554990\|ref\|YP_002387903.1\| putative NUDIX hydrolase [Escherichia coli IAI1], gi\|218361758\|emb\|... NUDK_SHIBS - GDP-mannose pyrophosphatase NudK OS=Shigella boydii serotype 4 (strain Sb227) GN=nudK PE=3 SV=1 gi\|75229211, gi\|... - gi\|75229211\|ref\|ZP_00715779.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ... NUDK_SHISS - GDP-mannose pyrophosphatase NudK OS=Shigella sonnei (strain Ss046) GN=nudK PE=3 SV=1	155.0	[0..1]	[191..1]
gi\|224467518, gi... - gi\|224582991\|ref\|YP_002636789.1\| hypothetical protein SPC_1183 [Salmonella enterica subsp. enterica ... gi\|197093051, gi... - gi\|197361575\|ref\|YP_002141211.1\| hypothetical protein SSPA0366 [Salmonella enterica subsp. enterica ... gi\|194470740, gi... - gi\|194470740\|ref\|ZP_03076724.1\| putative hydrolase YffH [Salmonella enterica subsp. enterica serovar... gi\|194450283, gi... - gi\|194450283\|ref\|YP_002046540.1\| putative hydrolase YffH [Salmonella enterica subsp. enterica serova... gi\|168466782, gi... - gi\|195630775\|gb\|EDX49367.1\| putative hydrolase YffH [Salmonella enterica subsp. enterica serovar New... gi\|205337642, gi... - gi\|205337642\|gb\|EDZ24406.1\| putative hydrolase YffH [Salmonella enterica subsp. enterica serovar Hei... gi\|168232021, gi... - gi\|205333525\|gb\|EDZ20289.1\| putative hydrolase YffH [Salmonella enterica subsp. enterica serovar Ken... NUDK_SALCH - GDP-mannose pyrophosphatase nudK OS=Salmonella choleraesuis GN=nudK PE=3 SV=1 NUDK_SALPB - GDP-mannose pyrophosphatase NudK OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=nudK PE=... NUDK_SALPA - GDP-mannose pyrophosphatase NudK OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=nudK PE=3 ... NUDK_SALPB - GDP-mannose pyrophosphatase nudK OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=nudK PE=... NUDK_SALCH - GDP-mannose pyrophosphatase NudK OS=Salmonella choleraesuis (strain SC-B67) GN=nudK PE=3 SV=1 NUDK_SALPA - GDP-mannose pyrophosphatase nudK OS=Salmonella paratyphi A GN=nudK PE=3 SV=1 NUDK_SALCH - GDP-mannose pyrophosphatase nudK OS=Salmonella choleraesuis GN=nudK PE=3 SV=1 gi\|238912890 - gi\|238912890\|ref\|ZP_04656727.1\| hypothetical protein SentesTe_17409 [Salmonella enterica subsp. ente...	154.0	[0..1]	[191..1]

Back

Predicted Domain #1

Region A:
Residues: [1-191]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQQITLIKD KILSDNYFTL HNITYDLTRK DGEVIRHKRE VYDRGNGATI LLYNAKKKSV  60
   61 VLIRQFRVAT WVNGNESGQL IETCAGLLDN DEPEVCIRKE AIEETGYEVG EVRKLFELYM 120
  121 SPGGVTELIH FFIAEYSDNQ RANAGGGVED EDIEVLELPF SQALEMIKTG EIRDGKTVLL 180
  181 LNYLQMSHLM D

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.69897
Match:	1viuA
Description:	Crystal structure of putative ADP ribose pyrophosphatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.49075808737475	bayes_pls_golite062009
hydrolase activity	0.914814648797509	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.60834739024706	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.608343780811364	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: