YRC Public Data Repository - Protein Structure Prediction

Protein:	RNPH_PSEA8
Organism:	Pseudomonas aeruginosa LESB58
Length:	239 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNPH_PSEA8.

Description	E-value	Query Range	Subject Range
gi\|107104436 - gi\|107104436\|ref\|ZP_01368354.1\| hypothetical protein PaerPA_01005513 [Pseudomonas aeruginosa PACS2]	4.0E-76	[1..239]	[1..239]
RNPH_PSEA7 - Ribonuclease PH OS=Pseudomonas aeruginosa (strain PA7) GN=rph PE=3 SV=1	6.0E-76	[1..239]	[1..239]
gi\|49082078 - gi\|49082078\|gb\|AAT50439.1\| PA5334 [synthetic construct]	5.0E-75	[1..239]	[1..239]
gi\|67154919 - gi\|67154919\|ref\|ZP_00416664.1\| Ribonuclease PH [Azotobacter vinelandii AvOP] RNPH_AZOVD - Ribonuclease PH OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=rph PE=3 SV=1	7.0E-74	[1..239]	[1..239]
gi\|71733440, gi\|... - gi\|71733440\|ref\|YP_272506.1\| ribonuclease PH [Pseudomonas syringae pv. phaseolicola 1448A], gi\|71553...	2.0E-73	[1..239]	[55..294]
RNPH_VIBF1 - Ribonuclease PH OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=rph PE=3 SV=1	2.0E-73	[3..239]	[2..238]
RNPH_PSEPF - Ribonuclease PH OS=Pseudomonas fluorescens (strain Pf0-1) GN=rph PE=3 SV=1	3.0E-73	[1..239]	[1..240]
gi\|72162764, gi\|... - gi\|72162764\|ref\|YP_290421.1\| ribonuclease PH [Thermobifida fusca YX], gi\|71916496\|gb\|AAZ56398.1\| RNA...	4.0E-73	[1..239]	[1..239]
gi\|46015433 - gi\|46015433\|pdb\|1R6L\|A Chain A, Crystal Structure Of The Trna Processing Enzyme Rnase Ph From Pseudo...	6.0E-73	[3..239]	[3..239]
gi\|95113322 - gi\|95113322\|emb\|CAK18050.1\| ribonuclease PH (RNase PH), tRNA nucleotidyltransferase [Pseudomonas ent... gi\|95113322, gi\|... - gi\|95113322\|emb\|CAK18050.1\| ribonuclease PH (RNase PH), tRNA nucleotidyltransferase [Pseudomonas ent...	9.0E-73	[1..239]	[14..253]

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Predicted Domain #1

Region A:
Residues: [1-239]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNRPSGRAAD QLRPIRITRH YTKHAEGSVL VEFGDTKVIC TVSAESGVPR FLKGQGQGWL  60
   61 TAEYGMLPRS TGERNQREAS RGKQGGRTLE IQRLIGRSLR AALDLSKLGE NTLYIDCDVI 120
  121 QADGGTRTAS ITGATVALID ALAVLKKRGA LKGNPLKQMV AAVSVGIYQG VPVLDLDYLE 180
  181 DSAAETDLNV VMTDAGGFIE VQGTAEGAPF RPAELNAMLE LAQQGMQELF ELQRAALAE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	77.154902
Match:	1r6lA
Description:	Crystal Structure Of The tRNA Processing Enzyme Rnase pH From Pseudomonas Aeruginosa
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
exoribonuclease activity	7.55877202113513	bayes_pls_golite062009
ribonuclease activity	7.54644729272203	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	7.5310318714913	bayes_pls_golite062009
3'-5'-exoribonuclease activity	6.46930372693262	bayes_pls_golite062009
3'-5' exonuclease activity	4.29895100594643	bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	3.83939403332553	bayes_pls_golite062009
exonuclease activity	3.40686901061667	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	2.86434572018929	bayes_pls_golite062009
structural constituent of ribosome	1.90115575554186	bayes_pls_golite062009
structural molecule activity	1.69321127364043	bayes_pls_golite062009
hydrolase activity	1.55476709794855	bayes_pls_golite062009
RNA binding	1.36549953164096	bayes_pls_golite062009
transcription regulator activity	1.20748032530392	bayes_pls_golite062009
nucleic acid binding	1.05662964529454	bayes_pls_golite062009
binding	0.907487229190259	bayes_pls_golite062009
catalytic activity	0.878454819018611	bayes_pls_golite062009
DNA binding	0.828609700556836	bayes_pls_golite062009
nuclease activity	0.69721312877891	bayes_pls_golite062009
tRNA-specific ribonuclease activity	0.383567539949931	bayes_pls_golite062009
mRNA binding	0.17546516359584	bayes_pls_golite062009
ATP-dependent peptidase activity	0.1173709890655	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: