YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|189375634, gi...
Organism:	Escherichia coli O157:H7 str. EC508
Length:	289 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|189375634, gi....

Description	E-value	Query Range	Subject Range
gi\|215265138, gi... - gi\|215487066\|ref\|YP_002329497.1\| DNA-binding transcriptional regulator HexR [Escherichia coli O127:H... gi\|117624005, gi... - gi\|117624005\|ref\|YP_852918.1\| DNA-binding transcriptional regulator HexR [Escherichia coli APEC O1],... gi\|218558718, gi... - gi\|218558718\|ref\|YP_002391631.1\| DNA-binding transcriptional regulator HexR [Escherichia coli S88], ... gi\|226900564, gi... - gi\|237705807\|ref\|ZP_04536288.1\| hex regulon repressor [Escherichia sp. 3_2_53FAA], gi\|226900564\|gb\|E... gi\|218689791, gi... - gi\|218689791\|ref\|YP_002398003.1\| DNA-binding transcriptional regulator HexR [Escherichia coli ED1a],... gi\|227885719, gi... - gi\|227885719\|ref\|ZP_04003524.1\| DNA-binding transcriptional regulator HexR [Escherichia coli 83972],... gi\|91211078, gi\|... - gi\|91211078\|ref\|YP_541064.1\| DNA-binding transcriptional regulator HexR [Escherichia coli UTI89], gi... gi\|110343563, gi... - gi\|110641971\|ref\|YP_669701.1\| DNA-binding transcriptional regulator HexR [Escherichia coli 536], gi\|... gi\|75239726, gi\|... - gi\|75239726\|ref\|ZP_00723689.1\| COG1737: Transcriptional regulators [Escherichia coli F11], gi\|191172... gi\|26108522, gi\|... - gi\|26248119\|ref\|NP_754159.1\| DNA-binding transcriptional regulator HexR [Escherichia coli CFT073], g...	232.0	[0..1]	[289..1]
gi\|124530953, gi... - gi\|124530953\|ref\|ZP_01701409.1\| transcriptional regulator, RpiR family [Escherichia coli B], gi\|1244... gi\|170019802, gi... - gi\|170019802\|ref\|YP_001724756.1\| DNA-binding transcriptional regulator HexR [Escherichia coli ATCC 8... gi\|218695419, gi... - gi\|218695419\|ref\|YP_002403086.1\| DNA-binding transcriptional regulator HexR [Escherichia coli 55989]... gi\|169889344, gi... - gi\|170081509\|ref\|YP_001730829.1\| DNA-binding transcriptional regulator [Escherichia coli str. K-12 s... gi\|238901068, gi... - gi\|238901068\|ref\|YP_002926864.1\| putative DNA-binding transcriptional regulator [Escherichia coli BW... gi\|242377574, gi... - gi\|251785301\|ref\|YP_002999605.1\| hypothetical protein B21_01812 [Escherichia coli BL21], gi\|24237757... gi\|192926292, gi... - gi\|75255868\|ref\|ZP_00727607.1\| COG1737: Transcriptional regulators [Escherichia coli E22], gi\|193066... gi\|254288701, gi... - gi\|254288701\|ref\|YP_003054449.1\| predicted DNA-binding transcriptional regulator [Escherichia coli B... EG12860 - putative DNA-binding transcriptional regulator / Function unknown; P. aeruginosa homolog represses z... gi\|75511824, gi\|... - gi\|75511824\|ref\|ZP_00734442.1\| COG1737: Transcriptional regulators [Escherichia coli 53638], gi\|1884... gi\|89108693, gi\|... - gi\|89108693\|ref\|AP_002473.1\| predicted DNA-binding transcriptional regulator [Escherichia coli str. ... gi\|254161913, gi... - gi\|254161913\|ref\|YP_003045021.1\| predicted DNA-binding transcriptional regulator [Escherichia coli B... gi\|81245088, gi\|... - gi\|82543677\|ref\|YP_407624.1\| DNA-binding transcriptional regulator HexR [Shigella boydii Sb227], gi\|... HEXR_ECOLI - HTH-type transcriptional regulator hexR (Hex regulon repressor) - Escherichia coli gi\|195182915 - gi\|195182915\|dbj\|BAG66483.1\| predicted protein [Escherichia coli O111:H-] gi\|194422044, gi... - gi\|83585546\|ref\|ZP_00924190.1\| COG1737: Transcriptional regulators [Escherichia coli 101-1], gi\|1944... EG12860 - putative DNA-binding transcriptional regulator / Function unknown; P. aeruginosa homolog represses z... gi\|157161322, gi... - gi\|75195918\|ref\|ZP_00705988.1\| COG1737: Transcriptional regulators [Escherichia coli HS], gi\|1571613... gi\|194412296, gi... - gi\|75209101\|ref\|ZP_00709356.1\| COG1737: Transcriptional regulators [Escherichia coli B171], gi\|19442...	231.0	[0..1]	[289..1]
gi\|110615345, gi... - gi\|110805797\|ref\|YP_689317.1\| DNA-binding transcriptional regulator HexR [Shigella flexneri 5 str. 8...	231.0	[0..1]	[289..1]
gi\|206708395, gi... - gi\|207856592\|ref\|YP_002243243.1\| DNA-binding transcriptional regulator HexR [Salmonella enterica sub... lcl\|NC_016856.1_... - [gene=yebK] [protein=DNA-binding transcriptional regulator HexR] [protein_id=YP_005237849.1] [locati... gi\|224583610, gi... - gi\|224583610\|ref\|YP_002637408.1\| putative hex-regulon repressor [Salmonella enterica subsp. enterica... gi\|197362120, gi... - gi\|197362120\|ref\|YP_002141757.1\| DNA-binding transcriptional regulator HexR [Salmonella enterica sub... gi\|16420423, gi\|... - gi\|16765229\|ref\|NP_460844.1\| DNA-binding transcriptional regulator HexR [Salmonella typhimurium LT2]... gi\|198244289, gi... - gi\|198244289\|ref\|YP_002215199.1\| HTH-type transcriptional regulator HexR [Salmonella enterica subsp.... gi\|168259840, gi... - gi\|205350540\|gb\|EDZ37171.1\| HTH-type transcriptional regulator HexR [Salmonella enterica subsp. ente... gi\|56127451, gi\|... - gi\|56413194\|ref\|YP_150269.1\| DNA-binding transcriptional regulator HexR [Salmonella enterica subsp. ... gi\|197242688, gi... - gi\|197264433\|ref\|ZP_03164507.1\| HTH-type transcriptional regulator HexR [Salmonella enterica subsp. ... gi\|205322917, gi... - gi\|205322917\|gb\|EDZ10756.1\| HTH-type transcriptional regulator HexR [Salmonella enterica subsp. ente... gi\|205328202, gi... - gi\|205328202\|gb\|EDZ14966.1\| HTH-type transcriptional regulator HexR [Salmonella enterica subsp. ente... gi\|161613559, gi... - gi\|161613559\|ref\|YP_001587524.1\| DNA-binding transcriptional regulator HexR [Salmonella enterica sub...	231.0	[0..1]	[289..1]
gi\|108811705, gi... - gi\|108811705\|ref\|YP_647472.1\| hex regulon repressor [Yersinia pestis Nepal516], gi\|108775353\|gb\|ABG1... gi\|108807444, gi... - gi\|108807444\|ref\|YP_651360.1\| hex regulon repressor [Yersinia pestis Antiqua], gi\|108779357\|gb\|ABG13... gi\|145598352, gi... - gi\|145598352\|ref\|YP_001162428.1\| DNA-binding transcriptional regulator HexR [Yersinia pestis Pestoid... gi\|22126131, gi\|... - gi\|22126131\|ref\|NP_669554.1\| hypothetical protein y2245 [Yersinia pestis KIM], gi\|21959091\|gb\|AAM858... gi\|45441710, gi\|... - gi\|45441710\|ref\|NP_993249.1\| Transcriptional regulators [Yersinia pestis biovar Microtus str. 91001]...	231.0	[0..1]	[284..53]
gi\|74311824, gi\|... - gi\|74311824\|ref\|YP_310243.1\| DNA-binding transcriptional regulator HexR [Shigella sonnei Ss046], gi\|...	231.0	[0..1]	[289..1]
gi\|204320011, gi... - gi\|204930967\|ref\|ZP_03221793.1\| HTH-type transcriptional regulator HexR [Salmonella enterica subsp. ... gi\|197250084, gi... - gi\|197250084\|ref\|YP_002146136.1\| HTH-type transcriptional regulator HexR [Salmonella enterica subsp.... gi\|238912053 - gi\|238912053\|ref\|ZP_04655890.1\| DNA-binding transcriptional regulator HexR [Salmonella enterica subs... gi\|194736565, gi... - gi\|194736565\|ref\|YP_002114922.1\| HTH-type transcriptional regulator HexR [Salmonella enterica subsp.... gi\|194455481, gi... - gi\|194469117\|ref\|ZP_03075101.1\| HTH-type transcriptional regulator HexR [Salmonella enterica subsp. ... gi\|25303537, gi\|... - gi\|25303537\|pir\|\|AC0742 probable hex-regulon repressor STY2095 [imported] - Salmonella enterica subs... gi\|29137098, gi\|... - gi\|29141471\|ref\|NP_804813.1\| DNA-binding transcriptional regulator HexR [Salmonella enterica subsp. ... gi\|214002659 - gi\|214002659\|ref\|ZP_03413394.1\| DNA-binding transcriptional regulator HexR [Salmonella enterica subs... gi\|213854140 - gi\|213854140\|ref\|ZP_03382672.1\| DNA-binding transcriptional regulator HexR [Salmonella enterica subs... gi\|213426412 - gi\|213426412\|ref\|ZP_03359162.1\| DNA-binding transcriptional regulator HexR [Salmonella enterica subs... gi\|205339514, gi... - gi\|205339514\|gb\|EDZ26278.1\| HTH-type transcriptional regulator HexR [Salmonella enterica subsp. ente... gi\|197288657, gi... - gi\|197288657\|gb\|EDY28032.1\| HTH-type transcriptional regulator HexR (Hex regulon repressor) [Salmone... gi\|16760837 - gi\|16760837\|ref\|NP_456454.1\| DNA-binding transcriptional regulator HexR [Salmonella enterica subsp. ... gi\|168233705, gi... - gi\|205332250\|gb\|EDZ19014.1\| HTH-type transcriptional regulator HexR [Salmonella enterica subsp. ente... gi\|194449540, gi... - gi\|194449540\|ref\|YP_002045940.1\| DNA-binding transcriptional regulator HexR [Salmonella enterica sub... gi\|194401157, gi... - gi\|194442494\|ref\|YP_002041152.1\| HTH-type transcriptional regulator HexR [Salmonella enterica subsp.... gi\|168820707, gi... - gi\|205342680\|gb\|EDZ29444.1\| HTH-type transcriptional regulator HexR [Salmonella enterica subsp. ente... gi\|168462584, gi... - gi\|195634465\|gb\|EDX52817.1\| HTH-type transcriptional regulator HexR [Salmonella enterica subsp. ente...	230.0	[0..1]	[289..1]
gi\|157155435, gi... - gi\|75190882\|ref\|ZP_00704149.1\| COG1737: Transcriptional regulators [Escherichia coli E24377A], gi\|15...	230.0	[0..1]	[289..1]
gi\|62128096, gi\|... - gi\|62180463\|ref\|YP_216880.1\| DNA-binding transcriptional regulator HexR [Salmonella enterica subsp. ...	229.0	[0..1]	[289..1]
gi\|49611931, gi\|... - gi\|50121405\|ref\|YP_050572.1\| DNA-binding transcriptional regulator HexR [Pectobacterium atrosepticum...	229.0	[0..1]	[282..1]

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Predicted Domain #1

Region A:
Residues: [1-289]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNMLEKIQSQ LEHLSKSERK VAEVILASPD NAIHSSIAAL ALEANVSEPT VNRFCRSMDT  60
   61 RGFPDFKLHL AQSLANGTPY VNRNVNEDDS VESYTGKIFE SAMATLDHVR HSLDKSAINR 120
  121 AVDLLTQAKK IAFFGLGSSA AVAHDAMNKF FRFNVPVVYS DDIVLQRMSC MNCSDGDVVV 180
  181 LISHTGRTKN LVELAQLARE NDAMVIALTS AGTPLAREAT LAITLDVPED TDIYMPMVSR 240
  241 LAQLTVIDVL ATGFTLRRGA KFRDNLKRVK EALKESRFDK QLLNLSDDR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.39794
Match:	1jxaA
Description:	"Isomerase domain" of glucosamine 6-phosphate synthase (GLMS); Glucosamine 6-phosphate synthase, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.5278037255884	bayes_pls_golite062009
binding	0.570536202654476	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: