YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|218754161
Organism:	Mycobacterium tuberculosis GM 1503
Length:	177 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|218754161.

Description	E-value	Query Range	Subject Range
AHPD_STRAW - Alkyl hydroperoxide reductase AhpD OS=Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM ... AHPD_STRAW - Alkyl hydroperoxide reductase AhpD OS=Streptomyces avermitilis GN=ahpD PE=3 SV=1	163.0	[0..1]	[176..1]
AHPD_STRCO - Alkyl hydroperoxide reductase AhpD OS=Streptomyces coelicolor GN=ahpD PE=3 SV=1 AHPD_STRCO - Alkyl hydroperoxide reductase AhpD OS=Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) G...	163.0	[0..1]	[176..1]
AHPD_CORDI - Alkyl hydroperoxide reductase AhpD OS=Corynebacterium diphtheriae GN=ahpD PE=3 SV=1 AHPD_CORDI - Alkyl hydroperoxide reductase AhpD OS=Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 /...	160.0	[0..1]	[172..1]
AHPD_MYCPA - Alkyl hydroperoxide reductase AhpD OS=Mycobacterium paratuberculosis GN=ahpD PE=3 SV=1 gi\|254775316 - gi\|254775316\|ref\|ZP_05216832.1\| AhpD [Mycobacterium avium subsp. avium ATCC 25291] AHPD_MYCPA - Alkyl hydroperoxide reductase AhpD OS=Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10) GN...	159.0	[0..1]	[177..1]
gi\|24159058, gi\|... - gi\|24159060\|pdb\|1ME5\|C Chain C, Crystal Structure Of Mycobacterium Tuberculosis Alkylperoxidase Ahpd...	154.0	[0..1]	[177..1]
AHPD_NOCFA - Alkyl hydroperoxide reductase AhpD OS=Nocardia farcinica GN=ahpD PE=3 SV=1 AHPD_NOCFA - Alkyl hydroperoxide reductase AhpD OS=Nocardia farcinica (strain IFM 10152) GN=ahpD PE=3 SV=1	149.0	[0..1]	[177..1]
gi\|84702543, gi\|... - gi\|84702543\|ref\|ZP_01017118.1\| AhpD, alkyl hydroperoxide reductase D [Parvularcula bermudensis HTCC2...	149.0	[0..1]	[175..1]
AHPD_BRUSI - Alkyl hydroperoxide reductase AhpD OS=Brucella suis (strain ATCC 23445 / NCTC 10510) GN=ahpD PE=3 SV... gi\|254699929 - gi\|254699929\|ref\|ZP_05161757.1\| alkylhydroperoxidase [Brucella suis bv. 5 str. 513] gi\|254705808 - gi\|254705808\|ref\|ZP_05167636.1\| alkylhydroperoxidase [Brucella pinnipedialis M163/99/10] AHPD_BRUME - Alkyl hydroperoxide reductase ahpD OS=Brucella melitensis GN=ahpD PE=3 SV=1 AHPD_BRUME - Alkyl hydroperoxide reductase AhpD OS=Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC ... gi\|254715573 - gi\|254715573\|ref\|ZP_05177384.1\| alkylhydroperoxidase [Brucella ceti M13/05/1] gi\|254711037 - gi\|254711037\|ref\|ZP_05172848.1\| alkylhydroperoxidase [Brucella pinnipedialis B2/94] gi\|254712500 - gi\|254712500\|ref\|ZP_05174311.1\| alkylhydroperoxidase [Brucella ceti M644/93/1]	146.0	[0..1]	[171..1]

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Predicted Domain #1

Region A:
Residues: [1-177]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIEKLKAAL PEYAKDIKLN LSSITRSSVL DQEQLWGTLL ASAAATRNPQ VLADIGAEAT  60
   61 DHLSAAARHA ALGAAAIMGM NNVFYRGRGF LEGRYDDLRP GLRMNIIANP GIPKANFELW 120
  121 SFAVSAINGC SHCLVAHEHT LRTVGVDREA IFEALKAAAI VSGVAQALAT IEALSPS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.522879
Match:	1gu9A
Description:	Antioxidant defence protein AhpD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.832094458002337	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: