YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|170082901, gi...
Organism:	Escherichia coli str. K-12 substr. DH10B
Length:	334 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|170082901, gi....

Description	E-value	Query Range	Subject Range
gi\|85060282, gi\|... - gi\|85060282\|ref\|YP_455984.1\| tryptophanyl-tRNA synthase [Sodalis glossinidius str. 'morsitans'], gi\|...	402.0	[0..1]	[334..1]
gi\|68057414, gi\|... - gi\|68249215\|ref\|YP_248327.1\| tryptophanyl-tRNA synthetase [Haemophilus influenzae 86-028NP], gi\|6805...	400.0	[0..1]	[331..3]
SYW_HAEIN - Tryptophanyl-tRNA synthetase OS=Haemophilus influenzae GN=trpS PE=3 SV=1 SYW_HAEIN - Tryptophan--tRNA ligase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN=trp...	400.0	[0..1]	[331..1]
gi\|229809654, gi... - gi\|229847416\|ref\|ZP_04467516.1\| tryptophanyl-tRNA synthetase [Haemophilus influenzae 7P49H1], gi\|229... gi\|46133005 - gi\|46133005\|ref\|ZP_00156437.2\| COG0180: Tryptophanyl-tRNA synthetase [Haemophilus influenzae R2866] gi\|42628929 - gi\|42628929\|ref\|ZP_00154481.1\| COG0180: Tryptophanyl-tRNA synthetase [Haemophilus influenzae R2846]	399.0	[0..1]	[331..1]
SYW_PASMU - Tryptophanyl-tRNA synthetase OS=Pasteurella multocida GN=trpS PE=3 SV=1 SYW_PASMU - Tryptophan--tRNA ligase OS=Pasteurella multocida (strain Pm70) GN=trpS PE=3 SV=1	398.0	[0..1]	[331..1]
gi\|50123007, gi\|... - gi\|50123007\|ref\|YP_052174.1\| tryptophanyl-tRNA synthetase [Pectobacterium atrosepticum SCRI1043], gi...	398.0	[0..1]	[334..1]
gi\|62129616, gi\|... - gi\|62181983\|ref\|YP_218400.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica serov... gi\|194712434, gi... - gi\|194736932\|ref\|YP_002116424.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica s... gi\|197214009, gi... - gi\|197250306\|ref\|YP_002148402.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica s... gi\|197265141, gi... - gi\|197265141\|ref\|ZP_03165215.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica se... gi\|197938888, gi... - gi\|198244372\|ref\|YP_002217442.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica s... gi\|205344545, gi... - gi\|205344545\|gb\|EDZ31309.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica serova... gi\|194443252, gi... - gi\|194443252\|ref\|YP_002042731.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica s... gi\|194450001, gi... - gi\|194450001\|ref\|YP_002047505.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica s... gi\|194470509, gi... - gi\|194470509\|ref\|ZP_03076493.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica se... gi\|197291441, gi... - gi\|197291441\|gb\|EDY30793.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica serova... gi\|168241618, gi... - gi\|205339049\|gb\|EDZ25813.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica serova... gi\|205350255, gi... - gi\|205350255\|gb\|EDZ36886.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica serova... gi\|168465255, gi... - gi\|195632456\|gb\|EDX50940.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica serova... gi\|161616517, gi... - gi\|161616517\|ref\|YP_001590482.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica s... gi\|205325695, gi... - gi\|205325695\|gb\|EDZ13534.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica serova... gi\|205327596, gi... - gi\|205327596\|gb\|EDZ14360.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica serova... gi\|205333050, gi... - gi\|205333050\|gb\|EDZ19814.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica serova... gi\|213648700 - gi\|213648700\|ref\|ZP_03378753.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica se... gi\|213865258 - gi\|213865258\|ref\|ZP_03387377.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica se... gi\|214000217 - gi\|214000217\|ref\|ZP_03410952.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica se... gi\|213053384 - gi\|213053384\|ref\|ZP_03346262.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica se... gi\|213423406 - gi\|213423406\|ref\|ZP_03356393.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica se... gi\|213426749 - gi\|213426749\|ref\|ZP_03359499.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica se... SYW_SALTY - Tryptophan--tRNA ligase OS=Salmonella typhimurium GN=trpS PE=3 SV=1 gi\|213610074 - gi\|213610074\|ref\|ZP_03369900.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica se... gi\|200388951, gi... - gi\|200388951\|ref\|ZP_03215563.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica se... gi\|205274676, gi... - gi\|205354895\|ref\|YP_002228696.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica s... SYW_SALTY - Tryptophanyl-tRNA synthetase OS=Salmonella typhimurium GN=trpS PE=3 SV=1 gi\|207858721, gi... - gi\|207858721\|ref\|YP_002245372.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica s... gi\|213026556 - gi\|213026556\|ref\|ZP_03341003.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica se... gi\|238913604 - gi\|238913604\|ref\|ZP_04657441.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica se... SYW_SALTI - Tryptophanyl-tRNA synthetase OS=Salmonella typhi GN=trpS PE=3 SV=1 lcl\|NC_016856.1_... - [gene=trpS] [protein=tryptophanyl-tRNA synthetase] [protein_id=YP_005239679.1] [location=complement(... SYW_SALTI - Tryptophan--tRNA ligase OS=Salmonella typhi GN=trpS PE=3 SV=1 gi\|16762806 - gi\|16762806\|ref\|NP_458423.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica serov... SYW_SALTY - Tryptophan--tRNA ligase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=trpS PE=3... gi\|29144293, gi\|... - gi\|29144293\|ref\|NP_807635.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica serov...	396.0	[0..1]	[334..1]
gi\|56129654, gi\|... - gi\|56415397\|ref\|YP_152472.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica serov... gi\|197095804, gi... - gi\|197364327\|ref\|YP_002143964.1\| tryptophanyl-tRNA synthetase [Salmonella enterica subsp. enterica s...	395.0	[0..1]	[334..1]
SYW_ENTAE - Tryptophan--tRNA ligase OS=Enterobacter aerogenes GN=trpS PE=3 SV=1 gi\|152972263, gi... - gi\|152972263\|ref\|YP_001337409.1\| tryptophanyl-tRNA synthetase [Klebsiella pneumoniae subsp. pneumoni... SYW_KLEAE - Tryptophanyl-tRNA synthetase OS=Klebsiella aerogenes GN=trpS PE=3 SV=1 gi\|238896852, gi... - gi\|238896852\|ref\|YP_002921597.1\| tryptophanyl-tRNA synthetase [Klebsiella pneumoniae NTUH-K2044], gi...	394.0	[0..1]	[334..1]
gi\|81242949, gi\|... - gi\|82778801\|ref\|YP_405150.1\| tryptophanyl-tRNA synthetase [Shigella dysenteriae Sd197], gi\|81242949\|... gi\|218550640, gi... - gi\|218550640\|ref\|YP_002384431.1\| tryptophanyl-tRNA synthetase [Escherichia fergusonii ATCC 35469], g... gi\|218367210, gi... - gi\|218560441\|ref\|YP_002393354.1\| tryptophanyl-tRNA synthetase [Escherichia coli S88], gi\|218367210\|e... gi\|218372113, gi... - gi\|218702127\|ref\|YP_002409756.1\| tryptophanyl-tRNA synthetase [Escherichia coli IAI39], gi\|218372113... gi\|191171594, gi... - gi\|75241526\|ref\|ZP_00725371.1\| COG0180: Tryptophanyl-tRNA synthetase [Escherichia coli F11], gi\|1911... SYW_ECO57 - Tryptophan--tRNA ligase OS=Escherichia coli O157:H7 GN=trpS PE=3 SV=1 SYW_ECOL6 - Tryptophan--tRNA ligase OS=Escherichia coli O6 GN=trpS PE=3 SV=1 gi\|254795298, gi... - gi\|254795298\|ref\|YP_003080135.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. TW14359... gi\|254038548, gi... - gi\|254038548\|ref\|ZP_04872604.1\| tryptophanyl-tRNA synthetase [Escherichia sp. 1_1_43], gi\|226839054\|... gi\|226902375, gi... - gi\|237703111\|ref\|ZP_04533592.1\| tryptophanyl-tRNA synthetase [Escherichia sp. 3_2_53FAA], gi\|2269023... gi\|227883514, gi... - gi\|227883514\|ref\|ZP_04001319.1\| tryptophanyl-tRNA synthetase [Escherichia coli 83972], gi\|227839393\|... gi\|168751805, gi... - gi\|188014192\|gb\|EDU52314.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4113], gi\|... gi\|209756700, gi... - pir\|\|H86002 tryptophan tRNA synthetase [imported] - Escherichia coli (strain O157:H7, substrain EDL... gi\|15803887, gi\|... - gi\|15803887\|ref\|NP_289923.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 EDL933], gi\|1251... gi\|91212856, gi\|... - gi\|91212856\|ref\|YP_542842.1\| tryptophanyl-tRNA synthetase [Escherichia coli UTI89], gi\|91074430\|gb\|A... gi\|117625652, gi... - gi\|117625652\|ref\|YP_858975.1\| tryptophanyl-tRNA synthetase [Escherichia coli APEC O1], gi\|115514776\|... SYW_ECOL6 - Tryptophan--tRNA ligase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=trpS PE=3 ... gi\|15833480, gi\|... - gi\|15833480\|ref\|NP_312253.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. Sakai], gi\|... gi\|194417123, gi... - gi\|194434664\|ref\|ZP_03066919.1\| tryptophanyl-tRNA synthetase [Shigella dysenteriae 1012], gi\|1944171... gi\|195934872 - gi\|195934872\|ref\|ZP_03080254.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4024] gi\|208806107, gi... - gi\|208806107\|ref\|ZP_03248444.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4206],... gi\|208811885, gi... - gi\|208811885\|ref\|ZP_03253214.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4045],... gi\|110345210, gi... - gi\|110643618\|ref\|YP_671348.1\| tryptophanyl-tRNA synthetase [Escherichia coli 536], gi\|110345210\|gb\|A... gi\|208821757, gi... - gi\|208821757\|ref\|ZP_03262077.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4042],... gi\|209397315, gi... - gi\|209397315\|ref\|YP_002272818.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4115]... gi\|215266737, gi... - gi\|215488665\|ref\|YP_002331096.1\| tryptophanyl-tRNA synthetase [Escherichia coli O127:H6 str. E2348/6... gi\|217322551, gi... - gi\|217326330\|ref\|ZP_03442414.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. TW14588]... gi\|189358895, gi... - gi\|189358895\|gb\|EDU77314.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4401], gi\|... gi\|168759405, gi... - gi\|189369835\|gb\|EDU88251.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4501], gi\|... gi\|189364757, gi... - gi\|189364757\|gb\|EDU83176.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4486], gi\|... gi\|187771660, gi... - gi\|187771660\|gb\|EDU35504.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4196], gi\|... gi\|189002476, gi... - gi\|189002476\|gb\|EDU71462.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4076], gi\|... gi\|168785185, gi... - gi\|189374370\|gb\|EDU92786.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC869], gi\|1... gi\|189380076, gi... - gi\|189380076\|gb\|EDU98492.1\| tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC508], gi\|1... gi\|170518804, gi... - gi\|170681086\|ref\|YP_001745627.1\| tryptophanyl-tRNA synthetase [Escherichia coli SMS-3-5], gi\|1705188...	393.0	[0..1]	[334..1]

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Predicted Domain #1

Region A:
Residues: [1-334]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKPIVFSGA QPSGELTIGN YMGALRQWVN MQDDYHCIYC IVDQHAITVR QDAQKLRKAT  60
   61 LDTLALYLAC GIDPEKSTIF VQSHVPEHAQ LGWALNCYTY FGELSRMTQF KDKSARYAEN 120
  121 INAGLFDYPV LMAADILLYQ TNLVPVGEDQ KQHLELSRDI AQRFNALYGE IFKVPEPFIP 180
  181 KSGARVMSLL EPTKKMSKSD DNRNNVIGLL EDPKSVVKKI KRAVTDSDEP PVVRYDVQNK 240
  241 AGVSNLLDIL SAVTGQSIPE LEKQFEGKMY GHLKGEVADA VSGMLTELQE RYHRFRNDEA 300
  301 FLQQVMKDGA EKASAHASRT LKAVYEAIGF VAKP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	101.0
Match:	1i6kA
Description:	Tryptophanyl-tRNA synthetase (TrpRS)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity, forming carbon-oxygen bonds	7.16276509815667	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	7.16276509815667	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	7.13957775963187	bayes_pls_golite062009
ligase activity	6.11211476973434	bayes_pls_golite062009
tryptophan-tRNA ligase activity	5.34430928486195	bayes_pls_golite062009
glutamate-tRNA ligase activity	2.63681738794687	bayes_pls_golite062009
methionine-tRNA ligase activity	2.56893064485672	bayes_pls_golite062009
catalytic activity	2.37674226834122	bayes_pls_golite062009
tyrosine-tRNA ligase activity	1.88984817882585	bayes_pls_golite062009
arginine-tRNA ligase activity	1.50161401062914	bayes_pls_golite062009
cysteine-tRNA ligase activity	0.844943947059557	bayes_pls_golite062009
binding	0.535704308663141	bayes_pls_golite062009
nucleic acid binding	0.449504767632354	bayes_pls_golite062009
nucleotidyltransferase activity	0.2293846471193	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.126511747475258	bayes_pls_golite062009
glutamine-tRNA ligase activity	0.118292082006187	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: