YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|165992449, gi...
Organism:	Yersinia pestis biovar Antiqua str. E1979001
Length:	417 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|165992449, gi....

Description	E-value	Query Range	Subject Range
gi\|77958563, gi\|... - gi\|77958563\|ref\|ZP_00822594.1\| COG0112: Glycine/serine hydroxymethyltransferase [Yersinia bercovieri...	0.0	[1..417]	[1..417]
gi\|238796764, gi... - gi\|77963401\|ref\|ZP_00827211.1\| COG0112: Glycine/serine hydroxymethyltransferase [Yersinia mollaretii...	0.0	[1..417]	[1..417]
GLYA_SHELP - Serine hydroxymethyltransferase OS=Shewanella loihica (strain ATCC BAA-1088 / PV-4) GN=glyA PE=3 SV=...	2.0E-99	[1..416]	[1..416]
GLYA_YERP3 - Serine hydroxymethyltransferase OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=gl...	4.0E-99	[1..417]	[1..417]
GLYA1_ERWCT - Pyridoxal-phosphate-dependent serine hydroxymethyltransferase 1 OS=Erwinia carotovora subsp. atrosep... GLYA1_PECAS - Serine hydroxymethyltransferase 1 OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) G...	5.0E-99	[1..417]	[1..417]
GLYA_PHOLL - Serine hydroxymethyltransferase OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP... GLYA_PHOLL - Serine hydroxymethyltransferase OS=Photorhabdus luminescens subsp. laumondii GN=glyA PE=3 SV=1	1.0E-98	[1..417]	[1..417]
GLYA_HALHL - Serine hydroxymethyltransferase OS=Halorhodospira halophila (strain DSM 244 / SL1) GN=glyA PE=3 SV=1	2.0E-98	[1..416]	[1..415]
gi\|116218565, gi... - gi\|75817666\|ref\|ZP_00747990.1\| COG0112: Glycine/serine hydroxymethyltransferase [Vibrio cholerae V51... tr\|A0A085T7S0\|A0... - Serine hydroxymethyltransferase OS=Vibrio cholerae GN=glyA PE=3 SV=1	5.0E-98	[1..417]	[1..416]
GLYA_SHEB9 - Serine hydroxymethyltransferase OS=Shewanella baltica (strain OS195) GN=glyA PE=3 SV=1	6.0E-98	[1..416]	[1..416]
GLYA_SHEB5 - Serine hydroxymethyltransferase OS=Shewanella baltica (strain OS155 / ATCC BAA-1091) GN=glyA PE=3 SV...	8.0E-98	[1..416]	[1..416]

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Predicted Domain #1

Region A:
Residues: [1-417]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKREMNIAD YDADLWRAME QEVVRQEEHI ELIASENYTS PRVMQAQGSQ LTNKYAEGYP  60
   61 GKRYYGGCEY VDVVEQLAID RAKALFGADY ANVQPHSGSQ ANVAVYSALL KPGDTVLGMN 120
  121 LAHGGHLTHG SPVNFSGKLY NIVPYGIDES GQIDYEDLAR QAEIHKPKMI IGGFSAYSGI 180
  181 VDWAKMREIA DSIDAWFFVD MAHVAGLVAA GVYPNPVPHA HIVTTTTHKT LAGPRGGLIL 240
  241 AKGGDEDLYK KLNSSVFPGN QGGPLMHVIA GKAVALKEAM EPEFKIYQQQ VAKNAKAMVA 300
  301 VFLERGYKVV SGGTDNHLFL LDLVDKDITG KDADAALGRA NITVNKNSVP NDPKSPFVTS 360
  361 GVRIGSPAIT RRGFKEAESR ELAGWMCDVL DNINDEATIE RVKQKVLAIC ARLPVYA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	94.69897
Match:	1dfoA
Description:	Serine hydroxymethyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glycine dehydrogenase (decarboxylating) activity	3.2128372762799	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	3.2128372762799	bayes_pls_golite062009
transferase activity	2.59075614411581	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	2.35743383627426	bayes_pls_golite062009
catalytic activity	2.29878871754893	bayes_pls_golite062009
transcription regulator activity	1.67701710033155	bayes_pls_golite062009
DNA binding	1.4774443071095	bayes_pls_golite062009
nucleic acid binding	1.39741122443159	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
transcription factor activity	1.15775909410582	bayes_pls_golite062009
binding	1.09053123792737	bayes_pls_golite062009
O-phospho-L-serine:2-oxoglutarate aminotransferase activity	0.994935084630764	bayes_pls_golite062009
methyltransferase activity	0.681623261233707	bayes_pls_golite062009
vitamin binding	0.66463470119531	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.60304280865376	bayes_pls_golite062009
5-aminolevulinate synthase activity	0.54326874956263	bayes_pls_golite062009
L-allo-threonine aldolase activity	0.500744432308415	bayes_pls_golite062009
structural molecule activity	0.347975812448725	bayes_pls_golite062009
transferase activity, transferring acyl groups	0.319452731970428	bayes_pls_golite062009
glycine hydroxymethyltransferase activity	0.271623203801431	bayes_pls_golite062009
pyridoxal phosphate binding	0.16957228630576	bayes_pls_golite062009
vitamin B6 binding	0.16957228630576	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: