YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|167050633, gi...
Organism:	Yersinia pestis biovar Antiqua str. UG05-0454
Length:	320 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|167050633, gi....

Description	E-value	Query Range	Subject Range
gi\|77963078, gi\|... - gi\|77963078\|ref\|ZP_00826891.1\| COG0492: Thioredoxin reductase [Yersinia mollaretii ATCC 43969], gi\|2...	6.0E-64	[1..320]	[1..320]
gi\|77958333, gi\|... - gi\|77958333\|ref\|ZP_00822368.1\| COG0492: Thioredoxin reductase [Yersinia bercovieri ATCC 43970], gi\|2...	2.0E-63	[1..320]	[1..320]
gi\|226898332, gi... - gi\|237707122\|ref\|ZP_04537603.1\| thioredoxin reductase [Escherichia sp. 3_2_53FAA], gi\|226898332\|gb\|E... gi\|26107314, gi\|... - gi\|26246914\|ref\|NP_752954.1\| thioredoxin reductase [Escherichia coli CFT073], gi\|26107314\|gb\|AAN7949... gi\|91071507, gi\|... - gi\|91209933\|ref\|YP_539919.1\| thioredoxin reductase [Escherichia coli UTI89], gi\|91071507\|gb\|ABE06388...	7.0E-63	[1..320]	[41..361]
gi\|238792415, gi... - gi\|77979250\|ref\|ZP_00834670.1\| COG0492: Thioredoxin reductase [Yersinia intermedia ATCC 29909], gi\|2...	1.0E-62	[1..320]	[1..320]
gi\|227838897, gi... - gi\|227884145\|ref\|ZP_04001950.1\| thioredoxin reductase [Escherichia coli 83972], gi\|227838897\|gb\|EEJ4... gi\|75240965 - gi\|75240965\|ref\|ZP_00724854.1\| COG0492: Thioredoxin reductase [Escherichia coli F11] gi\|117623072, gi... - gi\|117623072\|ref\|YP_851985.1\| thioredoxin reductase [Escherichia coli APEC O1], gi\|115512196\|gb\|ABJ0...	2.0E-62	[1..320]	[36..356]
gi\|72611379, gi\|... - gi\|74015950\|ref\|ZP_00686577.1\| Thioredoxin reductase [Burkholderia ambifaria AMMD], gi\|72611379\|gb\|E...	3.0E-62	[1..320]	[27..346]
gi\|37525546, gi\|... - gi\|37525546\|ref\|NP_928890.1\| thioredoxin reductase (NADPH) [Photorhabdus luminescens subsp. laumondi...	3.0E-62	[1..319]	[1..319]
gi\|42630036 - gi\|42630036\|ref\|ZP_00155580.1\| COG0492: Thioredoxin reductase [Haemophilus influenzae R2846]	7.0E-62	[1..317]	[1..317]
gi\|67545792, gi\|... - gi\|67545792\|ref\|ZP_00423711.1\| Thioredoxin reductase [Burkholderia vietnamiensis G4], gi\|67532861\|gb...	1.0E-61	[1..320]	[27..346]
gi\|115315235, gi... - gi\|115315235\|ref\|YP_763958.1\| thioredoxin reductase [Francisella tularensis subsp. holarctica OSU18]... gi\|167009257 - gi\|167009257\|ref\|ZP_02274188.1\| thioredoxin-disulfide reductase [Francisella tularensis subsp. holar... gi\|89256848, gi\|... - gi\|89256848\|ref\|YP_514210.1\| thioredoxin reductase [Francisella tularensis subsp. holarctica], gi\|89... gi\|254369730, gi... - gi\|254369730\|ref\|ZP_04985740.1\| thioredoxin reductase [Francisella tularensis subsp. holarctica FSC0... gi\|156253625, gi... - gi\|156503022\|ref\|YP_001429087.1\| thioredoxin reductase [Francisella tularensis subsp. holarctica FTN... gi\|89144679\|emb\|... - thioredoxin reductase [Francisella tularensis subsp. holarctica LVS]	1.0E-61	[4..316]	[2..314]

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Predicted Domain #1

Region A:
Residues: [1-320]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTAKHSKLI ILGSGPAGYT AAVYAARANL KPVLITGMEK GGQLTTTTEV ENWPGDPEGL  60
   61 TGPALMERMH EHAEKFQTEI IFDHISSVDL QNRPFRLFGD GAEYTCDALI IATGASARYL 120
  121 GMASEEAFKG KGVSACATCD GFFYRNQKVA VVGGGNTAVE EALYLANIAA EVHLIHRRDT 180
  181 FRSEKILIDR LMEKVKNGNI VLHTDRTLDE VLGDDMGVTG VRLKSTHSDE TEELAVAGVF 240
  241 IAIGHSPNTG IFSDQLALEN GYIKVQSGLQ GNATQTSIPG VFAAGDVMDH IYRQAITSAG 300
  301 TGCMAALDAE RYLDGLANDK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.045757
Match:	1cl0A
Description:	Thioredoxin reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
thioredoxin-disulfide reductase activity	3.42654162439464	bayes_pls_golite062009
antioxidant activity	3.37477730756688	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	3.17769237742078	bayes_pls_golite062009
catalytic activity	1.56773888754354	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	1.45104542724719	bayes_pls_golite062009
binding	1.4227698123368	bayes_pls_golite062009
oxidoreductase activity	0.44090433301056	bayes_pls_golite062009
oxygen-dependent protoporphyrinogen oxidase activity	0.1498172520052	bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity	0.130601418359425	bayes_pls_golite062009
protein binding	0.116927178396589	bayes_pls_golite062009
disulfide oxidoreductase activity	0.0160065137614933	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: