YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|168760366, gi...
Organism:	Escherichia coli O157:H7 str. EC4501
Length:	434 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|168760366, gi....

Description	E-value	Query Range	Subject Range
gi\|188494159, gi... - gi\|75514600\|ref\|ZP_00736855.1\| COG0524: Sugar kinases, ribokinase family [Escherichia coli 53638], g...	360.0	[0..1]	[434..1]
gi\|62179103, gi\|... - gi\|62179103\|ref\|YP_215520.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serovar C...	360.0	[0..1]	[434..16]
gi\|213427957 - gi\|213427957\|ref\|ZP_03360707.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serova... gi\|213613062 - gi\|213613062\|ref\|ZP_03370888.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serova... gi\|213865430 - gi\|213865430\|ref\|ZP_03387549.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serova... gi\|29142758, gi\|... - gi\|29142758\|ref\|NP_806100.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serovar T... gi\|16759470 - gi\|16759470\|ref\|NP_455087.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serovar T... gi\|16501762, gi\|... - gi\|25512666\|pir\|\|AF0563 inosine-guanosine kinase [imported] - Salmonella enterica subsp. enterica se... gi\|213416916 - gi\|213416916\|ref\|ZP_03350060.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serova...	358.0	[0..1]	[434..1]
gi\|16763871, gi\|... - gi\|16763871\|ref\|NP_459486.1\| inosine-guanosine kinase [Salmonella typhimurium LT2], gi\|16418999\|gb\|A... gi\|207855970, gi... - gi\|207855970\|ref\|YP_002242621.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serov... gi\|204930596, gi... - gi\|204930596\|ref\|ZP_03221526.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Javiana ... gi\|205271579, gi... - gi\|205351798\|ref\|YP_002225599.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serov... gi\|56414354, gi\|... - gi\|56414354\|ref\|YP_151429.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serovar P... gi\|197363274, gi... - gi\|197363274\|ref\|YP_002142911.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serov... gi\|200390186, gi... - gi\|200390186\|ref\|ZP_03216797.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Virchow ... gi\|197251769, gi... - gi\|197251769\|ref\|YP_002145475.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Agona s... gi\|197261690, gi... - gi\|197261690\|ref\|ZP_03161764.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Saintpau... gi\|194451001, gi... - gi\|194451001\|ref\|YP_002044524.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Heidelb... gi\|194712673, gi... - gi\|194737171\|ref\|YP_002113522.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Schwarz... gi\|195631744, gi... - gi\|195631744\|gb\|EDX50264.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Newport str.... gi\|194443043, gi... - gi\|194443043\|ref\|YP_002039735.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Newport... gi\|168240323, gi... - gi\|205340150\|gb\|EDZ26914.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Heidelberg s... gi\|205349759, gi... - gi\|205349759\|gb\|EDZ36390.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Hadar str. R... gi\|168239007, gi... - gi\|197288173\|gb\|EDY27558.1\| inosine kinase [Salmonella enterica subsp. enterica serovar Schwarzengru... gi\|238911379 - gi\|238911379\|ref\|ZP_04655216.1\| inosine-guanosine kinase [Salmonella enterica subsp. enterica serova...	358.0	[0..1]	[434..1]
gi\|9658227, gi\|1... - gi\|9658227\|gb\|AAF96699.1\| inosine-guanosine kinase [Vibrio cholerae O1 biovar eltor str. N16961], gi... gi\|229605576, gi... - gi\|229605576\|ref\|YP_002876280.1\| inosine-guanosine kinase [Vibrio cholerae MJ-1236], gi\|229372062\|gb... gi\|11355587 - pir\|\|H82414 inosine-guanosine kinase VCA0801 [imported] - Vibrio cholerae (strain N16961 serogroup O... gi\|229517771, gi... - gi\|229517771\|ref\|ZP_04407216.1\| inosine-guanosine kinase [Vibrio cholerae RC9], gi\|229345807\|gb\|EEO1... gi\|229510099, gi... - gi\|229510099\|ref\|ZP_04399579.1\| inosine-guanosine kinase [Vibrio cholerae B33], gi\|229352544\|gb\|EEO1... gi\|229506045, gi... - gi\|229506045\|ref\|ZP_04395554.1\| inosine-guanosine kinase [Vibrio cholerae BX 330286], gi\|229356396\|g... gi\|121588074, gi... - gi\|121588074\|ref\|ZP_01677823.1\| inosine-guanosine kinase [Vibrio cholerae 2740-80], gi\|121547670\|gb\|... gi\|227011509, gi... - gi\|227812367\|ref\|YP_002812377.1\| inosine-guanosine kinase [Vibrio cholerae M66-2], gi\|227011509\|gb\|A... gi\|153216450, gi... - gi\|153216450\|ref\|ZP_01950469.1\| inosine-guanosine kinase [Vibrio cholerae 1587], gi\|124114252\|gb\|EAY... gi\|124118109, gi... - gi\|153223559\|ref\|ZP_01953937.1\| inosine-guanosine kinase [Vibrio cholerae MAK 757], gi\|124118109\|gb\|... gi\|75829302, gi\|... - gi\|75829302\|ref\|ZP_00758610.1\| COG0524: Sugar kinases, ribokinase family [Vibrio cholerae MO10], gi\|...	357.0	[0..1]	[434..1]
gi\|147671584, gi... - gi\|75825326\|ref\|ZP_00754762.1\| COG0524: Sugar kinases, ribokinase family [Vibrio cholerae O395], gi\|... gi\|125620493, gi... - gi\|75819084\|ref\|ZP_00749183.1\| COG0524: Sugar kinases, ribokinase family [Vibrio cholerae V51], gi\|2... gi\|75823131, gi\|... - gi\|75823131\|ref\|ZP_00752659.1\| COG0524: Sugar kinases, ribokinase family [Vibrio cholerae RC385], gi... gi\|229348216, gi... - gi\|229514236\|ref\|ZP_04403697.1\| inosine-guanosine kinase [Vibrio cholerae TMA 21], gi\|229348216\|gb\|E... gi\|153802976, gi... - gi\|153802976\|ref\|ZP_01957562.1\| inosine-guanosine kinase [Vibrio cholerae MZO-3], gi\|124121499\|gb\|EA... tr\|A2PVX6\|A2PVX6... - Inosine-guanosine kinase OS=Vibrio cholerae MZO-3 GN=gsk-2 PE=4 SV=1, Inosine-guanosine kinase OS=Vi... gi\|197750634, gi... - gi\|254292034\|ref\|ZP_04962812.1\| inosine-guanosine kinase [Vibrio cholerae AM-19226], gi\|197750634\|re... gi\|153830489, gi... - gi\|153830489\|ref\|ZP_01983156.1\| inosine-guanosine kinase [Vibrio cholerae 623-39], gi\|148874022\|gb\|E...	357.0	[0..1]	[434..1]
gi\|81239941, gi\|... - gi\|82775793\|ref\|YP_402140.1\| inosine-guanosine kinase [Shigella dysenteriae Sd197], gi\|81239941\|gb\|A...	356.0	[0..1]	[434..1]
gi\|110804503, gi... - gi\|110804503\|ref\|YP_688023.1\| inosine-guanosine kinase [Shigella flexneri 5 str. 8401], gi\|110614051... gi\|30040221, gi\|... - gi\|30061977\|ref\|NP_836148.1\| inosine-guanosine kinase [Shigella flexneri 2a str. 2457T], gi\|30040221... gi\|24111860, gi\|... - gi\|24111860\|ref\|NP_706370.1\| inosine-guanosine kinase [Shigella flexneri 2a str. 301], gi\|24050656\|g...	356.0	[0..1]	[434..1]
gi\|90580028, gi\|... - gi\|90580028\|ref\|ZP_01235836.1\| Putative inosine-guanosine kinase [Vibrio angustum S14], gi\|90438913\|...	354.0	[0..1]	[434..1]
gi\|77974254, gi\|... - gi\|77974254\|ref\|ZP_00829795.1\| COG0524: Sugar kinases, ribokinase family [Yersinia frederiksenii ATC...	354.0	[0..1]	[434..1]

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Predicted Domain #1

Region A:
Residues: [1-434]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFPGKRKSK HYFPVNARDP LLQQFQPENE TSAAWVVGID QTLVDIEAKV DDEFIERYGL  60
   61 SAGHSLVIED DVAEALYQEL KQKNLITHQF AGGTIGNTMH NYSVLADDRS VLLGVMCSNI 120
  121 EIGSYAYRYL CNTSSRTDLN YLQGVDGPIG RCFTLIGESG ERTFAISPGH MNQLRAESIP 180
  181 EDVIAGASAL VLTSYLVRCK PGEPMPEATM KAIEYAKKYN VPVVLTLGTK FVIAENPQWW 240
  241 QQFLKDHVSI LAMNEDEAEA LTGESDPLLA SDKALDWVDL VLCTAGPIGL YMAGFTEDEA 300
  301 KRKTQHPLLP GAIAEFNQYE FSRAMRHKDC QNPLRVYSHI APYMGGPEKI MNTNGAGDGA 360
  361 LAALLHDITA NSYHRSNVPN SSKHKFTWLT YSSLAQVCKY ANRVSYQVLN QHSPRLTRGL 420
  421 PEREDSLEES YWDR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.69897
Match:	1tyyA
Description:	Crystal structure of aminoimidazole riboside kinase from Salmonella enterica
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
kinase activity	5.04206608489376	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	4.1090502214964	bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity	3.2648227748401	bayes_pls_golite062009
catalytic activity	2.11518580948187	bayes_pls_golite062009
transferase activity	1.65599843675995	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.53929419091344	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: