YRC Public Data Repository - Protein Structure Prediction

Protein:	UBIE_ECO5E
Organism:	Escherichia coli O157:H7 str. EC4115
Length:	251 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UBIE_ECO5E.

Description	E-value	Query Range	Subject Range
UBIE_ECOK1 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Escherichia coli O1:K1 / APEC GN=ubi... UBIE_ECOL6 - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Escherichia coli O6 GN=ubiE PE=3 SV=1 gi\|191173929, gi... - gi\|75237632\|ref\|ZP_00721652.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [E... UBIE_ECOL6 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Escherichia coli O6:H1 (strain CFT07... gi\|227888553, gi... - gi\|227888553\|ref\|ZP_04006358.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Escherichia c... UBIE_ECO45 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Escherichia coli O45:K1 (strain S88 ... gi\|226903039, gi... - gi\|237702868\|ref\|ZP_04533349.1\| ubiquinone/menaquinone biosynthesis methyltransferase ubiE [Escheric... UBIE_ECO81 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Escherichia coli O81 (strain ED1a) G... UBIE_ECOUT - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Escherichia coli (strain UTI89 / UPE... UBIE_ECOL5 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Escherichia coli O6:K15:H31 (strain ...	268.0	[0..1]	[251..1]
gi\|89074430, gi\|... - gi\|89074430\|ref\|ZP_01160907.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Photobacterium...	267.0	[0..1]	[251..1]
gi\|84386296, gi\|... - gi\|84386296\|ref\|ZP_00989324.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio splendi...	265.0	[0..6]	[251..19]
gi\|218321183, gi... - gi\|218708164\|ref\|YP_002415785.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio splen... gi\|85835662, gi\|... - gi\|86146605\|ref\|ZP_01064927.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio sp. MED...	265.0	[0..6]	[251..19]
gi\|194417704, gi... - gi\|83569331\|ref\|ZP_00920786.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [S...	265.0	[0..1]	[251..1]
UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... UBIE_VIBCM - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... gi\|229508366, gi... - gi\|229508366\|ref\|ZP_04397870.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229346129, gi... - gi\|229517066\|ref\|ZP_04406512.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229520118, gi... - gi\|229520118\|ref\|ZP_04409546.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229527169, gi... - gi\|229527169\|ref\|ZP_04416563.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|229369296, gi... - gi\|229606641\|ref\|YP_002877289.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vi... gi\|121587669, gi... - gi\|121587669\|ref\|ZP_01677432.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|124115249, gi... - gi\|153214643\|ref\|ZP_01949519.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|254851469, gi... - gi\|75829374\|ref\|ZP_00758679.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|153222877, gi... - gi\|153222877\|ref\|ZP_01953501.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|153801700, gi... - gi\|153801700\|ref\|ZP_01956286.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|116216422, gi... - gi\|75823221\|ref\|ZP_00752740.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|153818222, gi... - gi\|153818222\|ref\|ZP_01970889.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... UBIE_VIBC3 - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio cholerae serotype O1 (strain ... gi\|126520347, gi... - gi\|229508952\|ref\|ZP_04398442.1\| ubiquinone/menaquinone biosynthesis methyltransferase UbiE/COQ5 [Vib... gi\|121727801, gi... - gi\|75816414\|ref\|ZP_00746885.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V... gi\|254291829, gi... - gi\|254291829\|ref\|ZP_04962613.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... gi\|153829106, gi... - gi\|153829106\|ref\|ZP_01981773.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c... UBIE_VIBCH - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Vibrio cholerae GN=ubiE PE=3 SV=1 gi\|149739586, gi... - gi\|153826648\|ref\|ZP_01979315.1\| ubiquinone/menaquinone biosynthesis methlytransferase UbiE [Vibrio c...	265.0	[0..2]	[251..11]
gi\|90437723, gi\|... - gi\|90581027\|ref\|ZP_01236827.1\| ubiquinone/menaquinone biosynthesis methyltransferase [Vibrio angustu...	265.0	[0..1]	[251..1]
gi\|148231\|gb\|AAA... - o251 [Escherichia coli] gi\|148231 - gi\|148231\|gb\|AAA67628.1\| o251 [Escherichia coli]	264.0	[0..1]	[251..1]
UBIE_VIBVU - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio vulnificus (strain CMCP6) GN=... UBIE_VIBVY - Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE OS=Vibrio vulnificus (strain YJ016) GN=... UBIE_VIBVU - Ubiquinone/menaquinone biosynthesis methyltransferase ubiE OS=Vibrio vulnificus GN=ubiE PE=3 SV=1	264.0	[0..4]	[251..13]
gi\|194537307, gi... - gi\|75820016\|ref\|ZP_00750074.1\| COG2226: Methylase involved in ubiquinone/menaquinone biosynthesis [V...	263.0	[0..2]	[251..11]

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Predicted Domain #1

Region A:
Residues: [1-251]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDKSQETTH FGFQTVAKEQ KADMVAHVFH SVASKYDVMN DLMSFGIHRL WKRFTIDCSG  60
   61 VRRGQTVLDL AGGTGDLTAK FSRLVGETGK VVLADINESM LKMGREKLRN IGVIGNVEYV 120
  121 QANAEALPFP DNTFDCITIS FGLRNVTDKD KALRSMYRVL KPGGRLLVLE FSKPIIEPLS 180
  181 KAYDAYSFHV LPRIGSLVAN DADSYRYLAE SIRMHPDQDT LKAMMQDAGF ESVDYYNLTA 240
  241 GVVALHRGYK F

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	20.0
Match:	1ve3A
Description:	Crystal structure of PH0226 protein from Pyrococcus horikoshii OT3
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.25333584501255	bayes_pls_golite062009
transferase activity	1.07321114919891	bayes_pls_golite062009
oxidoreductase activity	0.964067575431689	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.612108481676679	bayes_pls_golite062009
methyltransferase activity	0.606225212585352	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	0.14147363365106	bayes_pls_golite062009
binding	0.109975487409217	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: