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View Structure Prediction Details

Protein: gi|207343912
Organism: Saccharomyces cerevisiae AWRI1631
Length: 539 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|207343912.

Description E-value Query
Range
Subject
Range
gi|207343912 - gi|207343912|gb|EDZ71226.1| YJR003Cp-like protein [Saccharomyces cerevisiae AWRI1631]
YJR003C - Putative protein of unknown function; detected in highly purified mitochondria in high-throughput st...
0.0 [1..539] [1..539]

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Predicted Domain #1
Region A:
Residues: [1-53]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKEFDESYFF KCLTANRHSI MLRSLHSAAT LSNKRFYSLI SHSNRKNIIK KLL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [83-93]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ESLNKLEVPK K

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [205-447]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNYNLPSELV EPILIYIVDN GIPNVLGSVL KYKIPLSFFD KYVSEMTQYQ ICELYDFYSL  60
   61 DNIVADPLVL HKCLTVLGEN EKIQQTEEEK EIISKLEEEI DIVKSQCHDN WSLEFPNWSV 120
  121 RKTATSFEEL FLEIQKRNID KKDFELAHKL LRLIGAFKGK VSLFFKLYDE YLLKFKNNED 180
  181 DLMFEAFLTL CCQGYKSSNE KMLQYAEAFI KEDFDSKLES KIQSVLIVAN AKANIDLSLK 240
  241 IYN

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.3
Match: 1n1bA
Description: (+)-bornyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [54-82]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RHPSFDPIRH HLPEDITTID PYSLSQNVI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [94-204]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DAAMVHNMMI ENLSDLDYGV ATIHSNNLRD LDLKPSLPAI KQIIRNNPGR VQSSWELFTQ  60
   61 YKASMENVPD ELMEVVLEKI IKFDKAEKVD GKKSLTYQDL VRCLYLINHF S

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 8.3
Match: 1n1bA
Description: (+)-bornyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [448-539]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNISTAKREK DKYTDLAESD VLTESLILAF LSRDDADFAR VIFDGALGEK LISGPTAAKK  60
   61 IKNLLAQYGE ALETKTSKQV MQTKIEHYME SI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.757 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.758 a.7.6 Ribosomal protein S20
View Download 0.743 a.118.11 Cytochrome c oxidase subunit E
View Download 0.914 a.29.4 RecG, N-terminal domain
View Download 0.773 a.29.4 RecG, N-terminal domain
View Download 0.702 a.7.6 Ribosomal protein S20
View Download 0.685 a.46.1 Methionine synthase domain
View Download 0.615 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.604 d.8.1 Urease, gamma-subunit
View Download 0.600 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.592 a.71.1 Endoplasmic reticulum protein ERP29, C-domain
View Download 0.569 a.118.11 Cytochrome c oxidase subunit E
View Download 0.500 a.64.1 Saposin
View Download 0.499 a.24.4 Hemerythrin
View Download 0.492 a.118.8 TPR-like
View Download 0.480 a.24.17 Group V grass pollen allergen
View Download 0.476 a.4.1 Homeodomain-like
View Download 0.469 a.29.4 RecG, N-terminal domain
View Download 0.468 a.64.1 Saposin
View Download 0.453 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.436 a.29.4 RecG, N-terminal domain
View Download 0.430 a.7.6 Ribosomal protein S20
View Download 0.427 a.64.1 Saposin
View Download 0.411 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.411 a.49.1 C-terminal domain of B transposition protein
View Download 0.408 a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.405 a.118.1 ARM repeat
View Download 0.394 a.4.5 "Winged helix" DNA-binding domain
View Download 0.385 a.118.8 TPR-like
View Download 0.381 a.64.1 Saposin
View Download 0.376 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.375 a.1.1 Globin-like
View Download 0.365 a.24.17 Group V grass pollen allergen
View Download 0.359 a.144.2 Ribosomal protein L20
View Download 0.358 a.56.1 CO dehydrogenase ISP C-domain like
View Download 0.355 b.34.8 Fumarylacetoacetate hydrolase, FAH, N-terminal domain
View Download 0.343 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.342 a.4.5 "Winged helix" DNA-binding domain
View Download 0.340 d.58.7 RNA-binding domain, RBD
View Download 0.339 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.333 a.64.1 Saposin
View Download 0.332 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.330 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.330 a.1.1 Globin-like
View Download 0.329 d.109.1 Actin depolymerizing proteins
View Download 0.324 a.11.1 Acyl-CoA binding protein
View Download 0.323 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.323 a.23.5 Hemolysin expression modulating protein HHA
View Download 0.321 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.320 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.318 a.4.5 "Winged helix" DNA-binding domain
View Download 0.318 a.29.4 RecG, N-terminal domain
View Download 0.316 a.39.1 EF-hand
View Download 0.314 a.77.1 DEATH domain
View Download 0.314 d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.308 a.4.5 "Winged helix" DNA-binding domain
View Download 0.305 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.304 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.299 a.29.2 Bromodomain
View Download 0.295 a.11.2 Second domain of FERM
View Download 0.294 b.46.1 FMT C-terminal domain-like
View Download 0.294 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.293 a.118.8 TPR-like
View Download 0.293 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.288 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.287 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.286 i.1.1 Ribosome and ribosomal fragments
View Download 0.283 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.282 d.49.1 Signal recognition particle alu RNA binding heterodimer, SRP9/14
View Download 0.279 c.78.2 Aspartate/glutamate racemase
View Download 0.276 a.61.1 Retroviral matrix proteins
View Download 0.275 a.61.1 Retroviral matrix proteins
View Download 0.274 a.39.1 EF-hand
View Download 0.273 a.11.2 Second domain of FERM
View Download 0.270 d.169.1 C-type lectin-like
View Download 0.270 a.17.1 p8-MTCP1
View Download 0.269 a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.269 a.4.5 "Winged helix" DNA-binding domain
View Download 0.265 a.11.2 Second domain of FERM
View Download 0.260 a.24.3 Cytochromes
View Download 0.257 a.40.1 Calponin-homology domain, CH-domain
View Download 0.256 a.4.5 "Winged helix" DNA-binding domain
View Download 0.255 a.4.5 "Winged helix" DNA-binding domain
View Download 0.254 a.133.1 Phospholipase A2, PLA2
View Download 0.251 a.12.1 Kix domain of CBP (creb binding protein)
View Download 0.251 a.118.8 TPR-like
View Download 0.250 a.71.2 Helical domain of Sec23/24
View Download 0.249 a.24.3 Cytochromes
View Download 0.247 a.133.1 Phospholipase A2, PLA2
View Download 0.246 a.65.1 Annexin
View Download 0.246 a.24.3 Cytochromes
View Download 0.245 a.118.8 TPR-like
View Download 0.241 a.46.1 Methionine synthase domain
View Download 0.238 a.118.9 ENTH/VHS domain
View Download 0.237 a.144.2 Ribosomal protein L20
View Download 0.230 a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.229 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.224 a.65.1 Annexin
View Download 0.224 a.4.1 Homeodomain-like
View Download 0.223 a.4.5 "Winged helix" DNA-binding domain
View Download 0.222 a.90.1 Transcription factor STAT-4 N-domain
View Download 0.222 a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.219 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.219 a.24.9 alpha-catenin/vinculin
View Download 0.218 a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.216 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.215 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.214 a.46.1 Methionine synthase domain
View Download 0.214 a.77.1 DEATH domain
View Download 0.211 b.82.4 Regulatory protein AraC
View Download 0.209 a.24.17 Group V grass pollen allergen
View Download 0.208 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.208 a.126.1 Serum albumin-like
View Download 0.208 d.58.1 4Fe-4S ferredoxins
View Download 0.207 a.77.1 DEATH domain
View Download 0.203 f.1.5 Exotoxin A, middle domain

Predicted Domain #4
Region A:
Residues: [451-539]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STAKREKDKY TDLAESDVLT ESLILAFLSR DDADFARVIF DGALGEKLIS GPTAAKKIKN  60
   61 LLAQYGEALE TKTSKQVMQT KIEHYMESI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.914 a.29.4 RecG, N-terminal domain
View Download 0.773 a.29.4 RecG, N-terminal domain
View Download 0.758 a.7.6 Ribosomal protein S20
View Download 0.757 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.743 a.118.11 Cytochrome c oxidase subunit E


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle