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View Structure Prediction Details

Protein: gi|190408997
Organism: Saccharomyces cerevisiae RM11-1a
Length: 479 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|190408997.

Description E-value Query
Range
Subject
Range
gi|14423562, gi|... - gi|30387583|gb|AAP31957.1| At2g44350 [Arabidopsis thaliana], gi|20197191|gb|AAC16084.2| citrate synt...
0.0 [1..477] [1..472]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [1..477] [1..473]
CISY_DAUCA - Citrate synthase, mitochondrial OS=Daucus carota GN=CS PE=2 SV=1
0.0 [1..474] [1..470]
gi|15982952 - gi|15982952|gb|AAL11504.1|AF367444_1 citrate synthase [Prunus persica]
0.0 [1..477] [1..472]
CISY_CITMA - Citrate synthase, mitochondrial OS=Citrus maxima GN=CIT PE=2 SV=1
0.0 [1..474] [1..469]
gi|190408997 - gi|190408997|gb|EDV12262.1| citrate synthase [Saccharomyces cerevisiae RM11-1a]
CISY1_YEAST - Citrate synthase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CIT1 PE=...
CIT1 - Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate; ...
0.0 [1..479] [1..479]
CISY_PIG - Citrate synthase, mitochondrial OS=Sus scrofa GN=CS PE=1 SV=2
gi|68227 - pir||YKPG citrate (si)-synthase (EC 4.1.3.7) precursor - pig
0.0 [19..472] [7..461]
CISY_MOUSE - Citrate synthase, mitochondrial OS=Mus musculus GN=Cs PE=1 SV=1
0.0 [19..472] [7..461]
CISY_RAT - Citrate synthase, mitochondrial OS=Rattus norvegicus GN=Cs PE=1 SV=1
0.0 [19..472] [7..461]
gi|11066954 - gi|11066954|gb|AAG28777.1|AF302906_1 citrate synthase [Oryza sativa]
0.0 [1..475] [1..470]

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Predicted Domain #1
Region A:
Residues: [1-316]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAILSTTSK SFLSRGSTRQ CQNMQKALFA LLNARHYSSA SEQTLKERFA EIIPAKAEEI  60
   61 KKFKKEHGKT VIGEVLLEQA YGGMRGIKGL VWEGSVLDPE EGIRFRGRTI PEIQRELPKA 120
  121 EGSTEPLPEA LFWLLLTGEI PTDAQVKALS ADLAARSEIP EHVIQLLDSL PKDLHPMAQF 180
  181 SIAVTALESE SKFAKAYAQG VSKKEYWSYT FEDSLDLLGK LPVIASKIYR NVFKDGKITS 240
  241 TDPNADYGKN LAQLLGYENK DFIDLMRLYL TIHSDHEGGN VSAHTTHLVG SALSSPYLSL 300
  301 AAGLNGLAGP LHGRAN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [421-479]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QYYGLTEASF YTVLFGVARA IGVLPQLIID RAVGAPIERP KSFSTEKYKE LVKKIESKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1849.0
Match: 1cts__
Description: Citrate synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
citrate (Si)-synthase activity 7.90380661459876 bayes_pls_golite062009
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer 7.35970609422108 bayes_pls_golite062009
transferase activity, transferring acyl groups 4.98392594633005 bayes_pls_golite062009
catalytic activity 2.51855037019879 bayes_pls_golite062009
transferase activity 2.22659761972612 bayes_pls_golite062009
binding 1.15467737113069 bayes_pls_golite062009
protein binding 0.210158634792359 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [317-420]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QEVLEWLFKL REEVKGDYSK ETIEKYLWDT LNAGRVVPGY GHAVLRKTDP RYTAQREFAL  60
   61 KHFPDYELFK LVSTIYEVAP GVLTKHGKTK NPWPNVDSHS GVLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1849.0
Match: 1cts__
Description: Citrate synthase
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle