YRC Public Data Repository - Protein Structure Prediction

Protein:	CLSA_SALPC
Organism:	Salmonella enterica subsp. enterica serovar Paratyphi C strain RKS4594
Length:	486 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CLSA_SALPC.

Description	E-value	Query Range	Subject Range
CLS_YERPS - Cardiolipin synthase OS=Yersinia pseudotuberculosis GN=cls PE=3 SV=1 CLSA_YERPB - Cardiolipin synthase A OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=clsA PE=3 SV=1 CLSA_YERPS - Cardiolipin synthase A OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=clsA PE=3 SV=1	0.0	[1..486]	[1..486]
gi\|77960752 - gi\|77960752\|ref\|ZP_00824610.1\| COG1502: Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin ...	0.0	[1..486]	[1..486]
gi\|149365891, gi... - gi\|149365891\|ref\|ZP_01887926.1\| cardiolipin synthetase [Yersinia pestis CA88-4125], gi\|149292304\|gb\|... gi\|16122418, gi\|... - gi\|218929286\|ref\|YP_002347161.1\| cardiolipin synthetase [Yersinia pestis CO92], gi\|16122418\|ref\|NP_4... CLSA_YERPP - Cardiolipin synthase A OS=Yersinia pestis (strain Pestoides F) GN=clsA PE=3 SV=1 CLSA_YERPG - Cardiolipin synthase A OS=Yersinia pestis bv. Antiqua (strain Angola) GN=clsA PE=3 SV=1 CLSA_YERP3 - Cardiolipin synthase A OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=clsA PE=3 S... gi\|166961781, gi... - gi\|167420086\|ref\|ZP_02311839.1\| cardiolipin synthetase [Yersinia pestis biovar Orientalis str. MG05-... gi\|167425026, gi... - gi\|167425026\|ref\|ZP_02316779.1\| cardiolipin synthetase [Yersinia pestis biovar Mediaevalis str. K197... gi\|229688545, gi... - gi\|229898255\|ref\|ZP_04513402.1\| cardiolipin synthase 1 [Yersinia pestis biovar Orientalis str. India... gi\|229693947, gi... - gi\|229897610\|ref\|ZP_04512766.1\| cardiolipin synthase 1 [Yersinia pestis biovar Orientalis str. PEXU2... CLSA_YERPE - Cardiolipin synthase A OS=Yersinia pestis GN=clsA PE=3 SV=1 gi\|229894864, gi... - gi\|229894864\|ref\|ZP_04510043.1\| cardiolipin synthase 1 [Yersinia pestis Pestoides A], gi\|229702157\|g... gi\|89104999, gi\|... - gi\|89104999\|ref\|ZP_01177527.1\| COG1502: Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin ... CLSA_YERPA - Cardiolipin synthase A OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=clsA PE=3 SV=1 CLSA_YERPN - Cardiolipin synthase A OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=clsA PE=3 SV=1 gi\|165920682, gi... - gi\|165927416\|ref\|ZP_02223248.1\| cardiolipin synthetase [Yersinia pestis biovar Orientalis str. F1991... gi\|166009253, gi... - gi\|166009253\|ref\|ZP_02230151.1\| cardiolipin synthetase [Yersinia pestis biovar Antiqua str. E1979001... gi\|166211179, gi... - gi\|166211179\|ref\|ZP_02237214.1\| cardiolipin synthetase [Yersinia pestis biovar Antiqua str. B4200300... gi\|167049832, gi... - gi\|167400979\|ref\|ZP_02306485.1\| cardiolipin synthetase [Yersinia pestis biovar Antiqua str. UG05-045...	0.0	[1..486]	[1..486]
gi\|22125925, gi\|... - gi\|22125925\|ref\|NP_669348.1\| cardiolipin synthetase [Yersinia pestis KIM], gi\|21958864\|gb\|AAM85599.1... gi\|45441787, gi\|... - gi\|45441787\|ref\|NP_993326.1\| cardiolipin synthetase [Yersinia pestis biovar Microtus str. 91001], gi...	0.0	[1..486]	[8..493]
gi\|77972671, gi\|... - gi\|77972671\|ref\|ZP_00828231.1\| COG1502: Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin ...	0.0	[1..486]	[1..486]
gi\|77977781, gi\|... - gi\|77977781\|ref\|ZP_00833221.1\| COG1502: Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin ...	0.0	[1..486]	[1..486]
gi\|77957084, gi\|... - gi\|77957084\|ref\|ZP_00821150.1\| COG1502: Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin ...	0.0	[1..486]	[1..486]
gi\|902467 - gi\|902467\|gb\|AAB60144.1\| cardiolipin synthase	0.0	[1..486]	[1..486]
CLSA_SHIBS - Cardiolipin synthase A OS=Shigella boydii serotype 4 (strain Sb227) GN=clsA PE=3 SV=1	0.0	[1..486]	[1..486]

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Predicted Domain #1

Region A:
Residues: [1-486]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTFYTVVSW LVILGYWVLI AGVTLRILMK RRAVPSAMAW LLIIYILPLV GIIAYLSVGE  60
   61 LHLGKRRAER ARAMWPSTAK WLNDLKACKH IFAQENSSVA SSLFKLCERR QGIAGVKGNQ 120
  121 LQLLTDSDDV MQALIRDIQL ARHNIEMVFY IWQPGGMADQ VAESLMAAAR RGIHCRLMLD 180
  181 SAGSVAFFRS PWAAMMRNAG IEVVEALKVN LMRVFLRRMD LRQHRKMVMI DNYIAYTGSM 240
  241 NMVDPRFFKQ DAGVGQWVDL MARMEGPVAT AMGIVYSCDW EIETGKRILP PPPDVNIMPF 300
  301 EQASGHTIHT IASGPGFPED LIHQALLTAT YAAREYLIMT TPYFVPSDDL LHAICTAAQR 360
  361 GVDVSIILPR KNDSLLVGWA SRAFFSELLA AGVKIYQFEG GLLHTKSVLV DGELSLVGTV 420
  421 NLDMRSLWLN FEITLVIDDT GFGADLAAVQ DDYISRSRLL DARLWVKRPL WQRITERLFY 480
  481 FFSPLL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.221849
Match:	1xdoA
Description:	Crystal Structure of Escherichia coli Polyphosphate Kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoric diester hydrolase activity	1.55477881010087	bayes_pls_golite062009
catalytic activity	1.29236214516383	bayes_pls_golite062009
binding	0.66572565048579	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.486367378916393	bayes_pls_golite062009
protein binding	0.162885453822356	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: