YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|190405645
Organism:	Saccharomyces cerevisiae RM11-1a
Length:	469 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|190405645.

Description	E-value	Query Range	Subject Range
gi\|190405645 - gi\|190405645\|gb\|EDV08912.1\| 3-phosphoglycerate dehydrogenase [Saccharomyces cerevisiae RM11-1a] SER3 - 3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozy... gi\|151944798 - gi\|151944798\|gb\|EDN63057.1\| 3-phosphoglycerate dehydrogenase [Saccharomyces cerevisiae YJM789] SERA_YEAST - D-3-phosphoglycerate dehydrogenase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SER...	0.0	[1..469]	[1..469]
SERA_SCHPO - Putative D-3-phosphoglycerate dehydrogenase OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) G... SPCC364.07 - D-3 phosphoglycerate dehydrogenase	0.0	[11..469]	[10..466]
gi\|15603536, gi\|... - gi\|15603536\|ref\|NP_246610.1\| D-3-phosphoglycerate dehydrogenase [Pasteurella multocida subsp. multoc...	0.0	[49..469]	[2..410]
SERA_HAEIN - D-3-phosphoglycerate dehydrogenase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 /... SERA_HAEIN - D-3-phosphoglycerate dehydrogenase OS=Haemophilus influenzae GN=serA PE=3 SV=1	0.0	[52..469]	[5..410]
gi\|149367076, gi... - gi\|149367076\|ref\|ZP_01889109.1\| D-3-phosphoglycerate dehydrogenase [Yersinia pestis CA88-4125], gi\|1... gi\|145597906, gi... - gi\|145597906\|ref\|YP_001161982.1\| D-3-phosphoglycerate dehydrogenase [Yersinia pestis Pestoides F], g... Q666Q8\|Q666Q8_YERPS - D-3-phosphoglycerate dehydrogenase - Yersinia pseudotuberculosis gi\|162351285, gi... - gi\|77635842\|ref\|ZP_00797922.1\| COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases [Y... gi\|229837603, gi... - gi\|229837603\|ref\|ZP_04457765.1\| D-3-phosphoglycerate dehydrogenase [Yersinia pestis Pestoides A], gi... gi\|77630166, gi\|... - gi\|77630166\|ref\|ZP_00792752.1\| COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases [Y... gi\|229840827, gi... - gi\|229840827\|ref\|ZP_04460986.1\| D-3-phosphoglycerate dehydrogenase [Yersinia pestis biovar Orientali... gi\|166212868, gi... - gi\|166212868\|ref\|ZP_02238903.1\| phosphoglycerate dehydrogenase [Yersinia pestis biovar Antiqua str. ... gi\|229690923, gi... - gi\|229842613\|ref\|ZP_04462768.1\| D-3-phosphoglycerate dehydrogenase [Yersinia pestis biovar Orientali... gi\|165990784, gi... - gi\|166010298\|ref\|ZP_02231196.1\| phosphoglycerate dehydrogenase [Yersinia pestis biovar Antiqua str. ... gi\|166963027, gi... - gi\|167419033\|ref\|ZP_02310786.1\| phosphoglycerate dehydrogenase [Yersinia pestis biovar Orientalis st... gi\|167399894, gi... - gi\|167399894\|ref\|ZP_02305412.1\| phosphoglycerate dehydrogenase [Yersinia pestis biovar Antiqua str. ... gi\|169749642, gi... - gi\|170023108\|ref\|YP_001719613.1\| D-3-phosphoglycerate dehydrogenase [Yersinia pseudotuberculosis YPI... gi\|167425272, gi... - gi\|167425272\|ref\|ZP_02317025.1\| phosphoglycerate dehydrogenase [Yersinia pestis biovar Mediaevalis s... gi\|186699647, gi... - gi\|186896621\|ref\|YP_001873733.1\| D-3-phosphoglycerate dehydrogenase [Yersinia pseudotuberculosis PB1... gi\|51597499, gi\|... - gi\|51597499\|ref\|YP_071690.1\| D-3-phosphoglycerate dehydrogenase [Yersinia pseudotuberculosis IP 3295... gi\|25283924 - pir\|\|AC0112 phosphoglycerate dehydrogenase (EC 1.1.1.95) [imported] - Yersinia pestis (strain CO92) gi\|16121219, gi\|... - gi\|218928087\|ref\|YP_002345962.1\| D-3-phosphoglycerate dehydrogenase [Yersinia pestis CO92], gi\|16121... gi\|165937338, gi... - gi\|89104319\|ref\|ZP_01176865.1\| COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases [Y... gi\|108778263, gi... - gi\|108806350\|ref\|YP_650266.1\| D-3-phosphoglycerate dehydrogenase [Yersinia pestis Antiqua], gi\|10877... gi\|165925145, gi... - gi\|165925145\|ref\|ZP_02220977.1\| phosphoglycerate dehydrogenase [Yersinia pestis biovar Orientalis st... gi\|229679501, gi... - gi\|229903731\|ref\|ZP_04518844.1\| D-3-phosphoglycerate dehydrogenase [Yersinia pestis Nepal516], gi\|22...	0.0	[49..469]	[1..413]
SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii GN=serA PE=3 SV=1 SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / ...	0.0	[60..468]	[3..390]
gi\|15642477, gi\|... - gi\|9657060\|gb\|AAF95623.1\| D-3-phosphoglycerate dehydrogenase [Vibrio cholerae O1 biovar El Tor str. ... gi\|11354856 - pir\|\|C82072 D-3-phosphoglycerate dehydrogenase VC2481 [imported] - Vibrio cholerae (strain N16961 se... gi\|116188123, gi... - gi\|75829170\|ref\|ZP_00758483.1\| COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases [V... gi\|146315088, gi... - gi\|75827743\|ref\|ZP_00757178.1\| COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases [V... gi\|75814144, gi\|... - gi\|75814144\|ref\|ZP_00744778.1\| COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases [V... gi\|229606966, gi... - gi\|229606966\|ref\|YP_002877614.1\| D-3-phosphoglycerate dehydrogenase [Vibrio cholerae MJ-1236], gi\|22... gi\|229344169, gi... - gi\|229519480\|ref\|ZP_04408923.1\| D-3-phosphoglycerate dehydrogenase [Vibrio cholerae RC9], gi\|2293441... gi\|121547398, gi... - gi\|121590757\|ref\|ZP_01678087.1\| D-3-phosphoglycerate dehydrogenase [Vibrio cholerae 2740-80], gi\|121... gi\|229507461, gi... - gi\|229507461\|ref\|ZP_04396966.1\| D-3-phosphoglycerate dehydrogenase [Vibrio cholerae BX 330286], gi\|2... gi\|124118869, gi... - gi\|153222432\|ref\|ZP_01953166.1\| D-3-phosphoglycerate dehydrogenase [Vibrio cholerae MAK 757], gi\|124... gi\|227082601, gi... - gi\|227082601\|ref\|YP_002811152.1\| D-3-phosphoglycerate dehydrogenase [Vibrio cholerae M66-2], gi\|2270... gi\|153819339, gi... - gi\|153819339\|ref\|ZP_01972006.1\| D-3-phosphoglycerate dehydrogenase [Vibrio cholerae NCTC 8457], gi\|1... gi\|153822868, gi... - gi\|229512344\|ref\|ZP_04401823.1\| D-3-phosphoglycerate dehydrogenase [Vibrio cholerae B33], gi\|2293523...	0.0	[49..469]	[1..409]
gi\|11360878 - pir\|\|B82587 D-3-phosphoglycerate dehydrogenase XF2206 [imported] - Xylella fastidiosa (strain 9a5c) gi\|15838797, gi\|... - gi\|9107351\|gb\|AAF85005.1\|AE004033_9 D-3-phosphoglycerate dehydrogenase [Xylella fastidiosa 9a5c], gi...	0.0	[48..469]	[2..413]
gi\|7431368 - gi\|7431368\|pir\|\|H69229 phosphoglycerate dehydrogenase - Methanobacterium thermoautotrophicum (strain... SERA_METTH - D-3-phosphoglycerate dehydrogenase OS=Methanothermobacter thermautotrophicus (strain ATCC 29096 / DS...	0.0	[58..468]	[3..391]

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Predicted Domain #1

Region A:
Residues: [1-152]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSIDINNLQ NTFQQAMNMS GSPGAVCTSP TQSFMNTVPQ RLNAVKHPKI LKPFSTGDMK  60
   61 ILLLENVNQT AITIFEEQGY QVEFYKSSLP EEELIEKIKD VHAIGIRSKT RLTSNVLQHA 120
  121 KNLVCIGCFC IGTNQVDLDY ATSRGIAVFN SP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [355-376]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQSSIGIEVA TALSKYINEG NS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1165.0
Match:	1psdA_
Description:	Phosphoglycerate dehydrogenase; Phosphoglycerate dehydrogenase, regulatory (C-terminal) domain
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [153-354]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSNSRSVAEL VIAEIISLAR QLGDRSIELH TGTWNKVAAR CWEVRGKTLG IIGYGHIGSQ  60
   61 LSVLAEAMGL HVLYYDIVTI MALGTARQVS TLDELLNKSD FVTLHVPATP ETEKMLSAPQ 120
  121 FAAMKDGAYV INASRGTVVD IPSLIQAVKA NKIAGAALDV YPHEPAKNGE GSFNDELNSW 180
  181 TSELVSLPNI ILTPHIGGST EE

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [377-469]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGSVNFPEVA LKSLSYDQEN TVRVLYIHQN VPGVLKTVND ILSNHNIEKQ FSDSNGEIAY  60
   61 LMADISSVDQ SDIKDIYEQL NQTSAKISIR LLY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1165.0
Match:	1psdA_
Description:	Phosphoglycerate dehydrogenase; Phosphoglycerate dehydrogenase, regulatory (C-terminal) domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits