YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|170022094, gi...
Organism:	Escherichia coli ATCC 8739
Length:	1016 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|170022094, gi....

Description	E-value	Query Range	Subject Range
gi\|51598212, gi\|... - gi\|51598212\|ref\|YP_072403.1\| formate dehydrogenase-O, major subunit (formate dehydrogenase... [Yersi...	927.0	[0..1]	[1016..1]
gi\|81243081, gi\|... - gi\|82778933\|ref\|YP_405282.1\| formate dehydrogenase-O, major subunit [Shigella dysenteriae Sd197], gi...	925.0	[0..1]	[1016..1]
FDOG_ECOLI - Formate dehydrogenase-O, major subunit - Escherichia coli (strain K12) FDOG_ECOLI - Formate dehydrogenase-O, major subunit (EC 1.2.1.2) (Formate dehydrogenase-O subunit alpha) (FDH-Z s...	925.0	[0..1]	[1016..1]
gi\|24054469, gi\|... - gi\|24115188\|ref\|NP_709698.1\| formate dehydrogenase-O, major subunit [Shigella flexneri 2a str. 301],... gi\|30064813, gi\|... - gi\|30064813\|ref\|NP_838984.1\| formate dehydrogenase-O, major subunit [Shigella flexneri 2a str. 2457T... gi\|110807416, gi... - gi\|110807416\|ref\|YP_690936.1\| formate dehydrogenase-O, major subunit [Shigella flexneri 5 str. 8401]...	924.0	[0..1]	[1016..1]
gi\|218354341, gi... - gi\|218697609\|ref\|YP_002405276.1\| formate dehydrogenase-O, large subunit [Escherichia coli 55989], gi... gi\|218363226, gi... - gi\|218556457\|ref\|YP_002389371.1\| formate dehydrogenase-O, large subunit [Escherichia coli IAI1], gi\|... gi\|73857873, gi\|... - gi\|74314396\|ref\|YP_312815.1\| formate dehydrogenase-O, major subunit [Shigella sonnei Ss046], gi\|7385... gi\|218701405, gi... - gi\|218701405\|ref\|YP_002409034.1\| formate dehydrogenase-O, large subunit [Escherichia coli IAI39], gi...	923.0	[0..1]	[1016..1]
gi\|15834074, gi\|... - gi\|15834074\|ref\|NP_312847.1\| formate dehydrogenase-O major subunit [Escherichia coli O157:H7 str. Sa... gi\|15834074, gi\|... - gi\|15834074\|ref\|NP_312847.1\| formate dehydrogenase-O major subunit [Escherichia coli O157:H7], gi\|13...	923.0	[0..1]	[1016..1]
gi\|26250659, gi\|... - gi\|26250659\|ref\|NP_756699.1\| formate dehydrogenase-O, major subunit [Escherichia coli CFT073], gi\|26...	922.0	[0..1]	[1016..1]
gi\|82546240, gi\|... - gi\|82546240\|ref\|YP_410187.1\| formate dehydrogenase-O, major subunit [Shigella boydii Sb227], gi\|8124...	922.0	[0..1]	[1016..1]
gi\|12518786, gi\|... - gi\|15804483\|ref\|NP_290523.1\| formate dehydrogenase-O, major subunit [Escherichia coli O157:H7 EDL933...	919.0	[0..1]	[1016..1]

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Predicted Domain #1

Region A:
Residues: [1-1016]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQVSRRQFFK ICAGGMAGTT AAALGFAPSV ALAETRQYKL LRTRETRNTC TYCSVGCGLL  60
   61 MYSLGDGAKN AKASIFHIEG DPDHPVNRGA LCPKGAGLVD FIHSESRLKF PEYRAPGSDK 120
  121 WQQISWEEAF DRIAKLMKED RDANYIAQNA EGVTVNRWLS TGMLCASASS NETGYLTQKF 180
  181 SRALGMLAVD NQARVUHGPT VASLAPTFGR GAMTNHWVDI KNANLVVVMG GNAAEAHPVG 240
  241 FRWAMEAKIH NGAKLIVIDP RFTRTAAVAD YYAPIRSGTD IAFLSGVLLY LLNNEKFNRE 300
  301 YTEAYTNASL IVREDYGFED GLFTGYDAEK RKYDKSSWTY ELDENGFAKR DTTLQHPRCV 360
  361 WNLLKQHVSR YTPDVVENIC GTPKDAFLKV CEYIAETSAH DKTASFLYAL GWTQHSVGAQ 420
  421 NIRTMAMIQL LLGNMGMAGG GVNALRGHSN IQGLTDLGLL SQSLPGYMTL PSEKQTDLQT 480
  481 YLTANTPKPL LEGQVNYWGN YPKFFVSMMK AFFGDKATAE NSWGFDWLPK WDKGYDVLQY 540
  541 FEMMKEGKVN GYICQGFNPV ASFPNKNKVI GCLSKLKFLV TIDPLNTETS NFWQNHGELN 600
  601 EVDSSKIQTE VFRLPSTCFA EENGSIVNSG RWLQWHWKGA DAPGIALTDG EILSGIFLRL 660
  661 RKMYAEQGGA NPDQVLNMTW NYAIPHEPSS EEVAMESNGK ALADITDPAT GAVIVKKGQQ 720
  721 LSSFAQLRDD GTTSCGCWIF AGSWTPEGNQ MARRDNADPS GLGNTLGWAW AWPLNRRILY 780
  781 NRASADPQGN PWDPKRQLLK WDGTKWTGWD IPDYSAAPPG SGVGPFIMQQ EGMGRLFALD 840
  841 KMAEGPFPEH YEPFETPLGT NPLHPNVISN PAARIFKDDA EALGKADKFP YVGTTYRLTE 900
  901 HFHYWTKHAL LNAILQPEQF VEIGESLANK LGIAQGDTVK VSSNRGYIKA KAVVTKRIRT 960
  961 LKANGKDIDT IGIPIHWGYE GVAKKGFIAN TLTPFVGDAN TQTPEFKSFL VNVEKV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1kqfA
Description:	Formate dehydrogenase N, alpha subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
formate dehydrogenase activity	12.8557183783781	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	7.57161550681607	bayes_pls_golite062009
oxidoreductase activity	7.18948979839656	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	7.16311737169172	bayes_pls_golite062009
electron carrier activity	2.49660481239302	bayes_pls_golite062009
nitrate reductase activity	2.20600951698793	bayes_pls_golite062009
catalytic activity	1.93875927205186	bayes_pls_golite062009
trimethylamine-N-oxide reductase activity	1.53833487723248	bayes_pls_golite062009
oxidoreductase activity, acting on other nitrogenous compounds as donors	1.12492792673137	bayes_pls_golite062009
4 iron, 4 sulfur cluster binding	1.10002765979078	bayes_pls_golite062009
molybdenum ion binding	1.06869099200697	bayes_pls_golite062009
iron-sulfur cluster binding	0.552726587326143	bayes_pls_golite062009
metal cluster binding	0.552726587326143	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	0.134493772161849	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: