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View Structure Prediction Details

Protein: gi|168278889
Organism: synthetic construct
Length: 672 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|168278889.

Description E-value Query
Range
Subject
Range
gi|114680845 - gi|114680845|ref|XP_514503.2| PREDICTED: similar to RP5-1022P6.2 isoform 2 [Pan troglodytes]
0.0 [1..672] [1..672]
gi|7243266 - gi|7243266|dbj|BAA92672.1| KIAA1434 protein [Homo sapiens]
0.0 [1..672] [6..677]
gi|73991641 - gi|73991641|ref|XP_542901.2| PREDICTED: similar to Protein KIAA1434 [Canis familiaris]
0.0 [1..672] [1..672]
GPCP1_MOUSE - Glycerophosphocholine phosphodiesterase GPCPD1 OS=Mus musculus GN=Gpcpd1 PE=1 SV=1
0.0 [1..672] [1..675]
GPCP1_RAT - Glycerophosphocholine phosphodiesterase GPCPD1 OS=Rattus norvegicus GN=Gpcpd1 PE=1 SV=1
0.0 [1..672] [1..672]
gi|80477596, gi|... - gi|80477596|gb|AAI08539.1| MGC130994 protein [Xenopus laevis], gi|148230549|ref|NP_001090135.1| hypo...
0.0 [5..668] [7..674]
gi|220956350 - gi|220956350|gb|ACL90718.1| CG2818-PA [synthetic construct]
CG2818-PA - This gene is referred to in FlyBase by the symbol Dmel\CG2818 (CG2818, FBgn0031566). It is a protein...
0.0 [7..635] [47..685]

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Predicted Domain #1
Region A:
Residues: [1-106]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPSQVAFEI RGTLLPGEVF AICGSCDALG NWNPQNAVAL LPENDTGESM LWKATIVLSR  60
   61 GVSVQYRYFK GYFLEPKTIG GPCQVIVHKW ETHLQPRSIT PLESEI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.69897
Match: 1ac0A
Description: GLUCOAMYLASE, GRANULAR STARCH-BINDING DOMAIN COMPLEX WITH CYCLODEXTRIN, NMR, MINIMIZED AVERAGE STRUCTURE
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [107-315]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IIDDGQFGIH NGVETLDSGW LTCQTEIRLR LHYSEKPPVS ITKKKLKKSR FRVKLTLEGL  60
   61 EEDDDDRVSP TVLHKMSNSL EISLISDNEF KCRHSQPECG YGLQPDRWTE YSIQTMEPDN 120
  121 LELIFDFFEE DLSEHVVQGD ALPGHVGTAC LLSSTIAESG KSAGILTLPI MSRNSRKTIG 180
  181 KVRVDYIIIK PLPGYSCDMK SSFSKYWKP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [316-672]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RIPLDVGHRG AGNSTTTAQL AKVQENTIAS LRNAASHGAA FVEFDVHLSK DFVPVVYHDL  60
   61 TCCLTMKKKF DADPVELFEI PVKELTFDQL QLLKLTHVTA LKSKDRKESV VQEENSFSEN 120
  121 QPFPSLKMVL ESLPEDVGFN IEIKWICQQR DGMWDGNLST YFDMNLFLDI ILKTVLENSG 180
  181 KRRIVFSSFD ADICTMVRQK QNKYPILFLT QGKSEIYPEL MDLRSRTTPI AMSFAQFENL 240
  241 LGINVHTEDL LRNPSYIQEA KAKGLVIFCW GDDTNDPENR RKLKELGVNG LIYDRIYDWM 300
  301 PEQPNIFQVE QLERLKQELP ELKSCLCPTV SRFVPSSLCG ESDIHVDANG IDNVENA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 54.221849
Match: 1ydyA
Description: Crystal structure of periplasmic glycerophosphodiester phosphodiesterase from Escherichia coli
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.322782393124324 bayes_pls_golite062009
hydrolase activity 0.114597543302679 bayes_pls_golite062009
phosphoric ester hydrolase activity 0.10444517300189 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.0391669406455814 bayes_pls_golite062009
phosphoric diester hydrolase activity 0.0229452028027644 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle