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View Structure Prediction Details

Protein: gi|195344085, gi...
Organism: Drosophila sechellia
Length: 374 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|195344085, gi....

Description E-value Query
Range
Subject
Range
Antp-PL, Antp-PJ... - The gene Antennapedia is referred to in FlyBase by the symbol Dmel\Antp (CG1028, FBgn0260642). It is...
152.0 [0..1] [374..1]

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Predicted Domain #1
Region A:
Residues: [1-190]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTMSTNNCES MTSYFTNSYM GADMHHGHYP GNGVTDLDAQ QMHHYSQNAN HQGNMPYPRF  60
   61 PPYDRMPYYN GQGMDQQQQH QVYSRPDSPS SQVGGVMPQA QTNGQLGVPQ QQQQQQQQPS 120
  121 QNQQQQQAQQ APQQLQQQLP QVTQQVTHPQ QQQQQPVVYA SCKLQAAVGG LGMVPEGGSP 180
  181 PLVDQMSGHH 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [191-295]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNAQMTLPHH MGHPQAQLGY TDVGVPDVTE VHQNHHNMGM YQQQSGVPPV GAPPQGMMHQ  60
   61 GQGPPQMHQG HPGQHTPPSQ NPNSQSSGMP SPLYPWMRSQ FERKR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [296-374]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRQTYTRYQT LELEKEFHFN RYLTRRRRIE IAHALCLTER QIKIWFQNRR MKWKKENKTK  60
   61 GEPGSGGEGD EITPPNSPQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 25.30103
Match: 1homA
Description: DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 2.6809639302471 bayes_pls_golite062009
DNA binding 2.45264254102339 bayes_pls_golite062009
nucleic acid binding 2.32767577674158 bayes_pls_golite062009
binding 2.12643314274039 bayes_pls_golite062009
transcription factor activity 1.9610710007594 bayes_pls_golite062009
sequence-specific DNA binding 0.71974400731667 bayes_pls_golite062009
protein binding 0.57484570028668 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.328460252819506 bayes_pls_golite062009
transcription repressor activity 0.245215140763955 bayes_pls_golite062009
transcription activator activity 0.0177888191364471 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle