YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|227074495, gi...
Organism:	Enterococcus faecalis TX0104
Length:	283 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|227074495, gi....

Description	E-value	Query Range	Subject Range
ISPE_BACCN - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 11...	280.0	[0..1]	[282..1]
ISPE_EXIS2 - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Exiguobacterium sibiricum (strain DSM 17290 / J...	278.0	[0..1]	[282..1]
ISPE_BACCR - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / J... ISPE_BACC4 - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Bacillus cereus (strain B4264) GN=ispE PE=3 SV=... gi\|206732506, gi... - gi\|206972604\|ref\|ZP_03233547.1\| 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase [Bacillus c... ISPE_BACC2 - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Bacillus cereus (strain G9842) GN=ispE PE=3 SV=...	278.0	[0..1]	[282..1]
gi\|68195792, gi\|... - gi\|69245410\|ref\|ZP_00603405.1\| 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Enterococcus faeciu... gi\|48825654 - ref\|ZP_00286895.1\| COG1947: 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase [Enteroco...	277.0	[0..1]	[282..1]
ISPE_BACWK - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Bacillus weihenstephanensis (strain KBAB4) GN=i...	276.0	[0..1]	[282..1]
ISPE_BACLD - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Bacillus licheniformis (strain ATCC 14580 / DSM...	276.0	[0..1]	[282..1]
ISPE_BACSU - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Bacillus subtilis GN=ispE PE=3 SV=1 gi\|221312177 - gi\|221312177\|ref\|ZP_03593982.1\| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Bacillus subtilis... ISPE_BACSU - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Bacillus subtilis (strain 168) GN=ispE PE=3 SV=... gi\|221317110 - gi\|221317110\|ref\|ZP_03598404.1\| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Bacillus subtilis... gi\|221321373 - gi\|221321373\|ref\|ZP_03602667.1\| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Bacillus subtilis...	275.0	[0..1]	[282..1]
gi\|74492898, gi\|... - gi\|75759607\|ref\|ZP_00739693.1\| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Bacillus thuringie...	274.0	[0..2]	[282..5]
ISPE_BACC3 - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Bacillus cereus (strain 03BB102) GN=ispE PE=3 S... gi\|196047375, gi... - gi\|196047375\|ref\|ZP_03114588.1\| 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Bacillus cereus 03... gi\|254724186 - gi\|254724186\|ref\|ZP_05185971.1\| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Bacillus anthraci... gi\|196027398, gi... - gi\|196041778\|ref\|ZP_03109068.1\| 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Bacillus cereus NV... gi\|254733604 - gi\|254733604\|ref\|ZP_05191323.1\| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Bacillus anthraci... ISPE_BACC0 - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Bacillus cereus (strain AH820) GN=ispE PE=3 SV=... ISPE_BACAC - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Bacillus anthracis (strain CDC 684 / NRRL 3495)... ISPE_BACC7 - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Bacillus cereus (strain AH187) GN=ispE PE=3 SV=... gi\|254682328 - gi\|254682328\|ref\|ZP_05146189.1\| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Bacillus anthraci... gi\|177655339, gi... - gi\|177655339\|ref\|ZP_02936868.1\| 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Bacillus anthracis... gi\|254762412 - gi\|254762412\|ref\|ZP_05214254.1\| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Bacillus anthraci... gi\|170667151, gi... - gi\|170688927\|ref\|ZP_02880129.1\| 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Bacillus anthracis... gi\|196036377, gi... - gi\|196036377\|ref\|ZP_03103774.1\| 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Bacillus cereus W]... gi\|254744651 - gi\|254744651\|ref\|ZP_05202330.1\| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Bacillus anthraci... ISPE_BACC1 - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) G... gi\|190569011, gi... - gi\|190569011\|ref\|ZP_03021912.1\| 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Bacillus anthracis... gi\|254756356 - gi\|254756356\|ref\|ZP_05208385.1\| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [Bacillus anthraci... gi\|164711702, gi... - gi\|165872574\|ref\|ZP_02217206.1\| 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Bacillus anthracis... gi\|167641543, gi... - gi\|167641543\|ref\|ZP_02399791.1\| 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Bacillus anthracis... gi\|167635068, gi... - gi\|167635068\|ref\|ZP_02393385.1\| 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Bacillus anthracis...	274.0	[0..1]	[282..1]
ISPE_BACSK - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase OS=Bacillus clausii (strain KSM-K16) GN=ispE PE=3 ...	272.0	[0..1]	[283..1]

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Predicted Domain #1

Region A:
Residues: [1-283]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEIIERAPAK INLGLDVLHK RVDGYHEVES IFASVDLADH LTFENLEEDI IRIETDSSFL  60
   61 PVDRRNHVYQ AVDLLKRTYN IHKGIKIYIE KRIPVAAGLA GGSSDCAAAL RGLNKLWNLG 120
  121 LTMDELCEIG SQIGMDVPYC LRGGTAFANG RGEKIEALPT MPQCWIVLVK PRISVSTSTV 180
  181 FNDLAVDELH HPDIAGLRIA IENGDYTGMT QTVGNALESV TIARHPIVQQ IKDRMLKYGA 240
  241 DAALMSGSGP TVFALCEKKT RAQRIYNGLK GFCEEVYLVR TLK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.045757
Match:	1oj4A
Description:	Ternary complex of 4-diphosphocytidyl-2C-methyl-D-erythritol kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity	1.9881460462076	bayes_pls_golite062009
catalytic activity	1.20658247466773	bayes_pls_golite062009
diphosphomevalonate decarboxylase activity	1.0502744466494	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: