YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|238913164
Organism:	Salmonella enterica subsp. enterica serovar Tennessee str. CDC07-0191
Length:	135 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|238913164.

Description	E-value	Query Range	Subject Range
gi\|24113042, gi\|... - gi\|24113042\|ref\|NP_707552.1\| glyoxalase I [Shigella flexneri 2a str. 301], gi\|24052010\|gb\|AAN43259.1... LGUL_SHIFL - Lactoylglutathione lyase OS=Shigella flexneri GN=gloA PE=3 SV=1 LGUL_ECO57 - Lactoylglutathione lyase OS=Escherichia coli O157:H7 GN=gloA PE=3 SV=1 gi\|30063167, gi\|... - gi\|30063167\|ref\|NP_837338.1\| glyoxalase I [Shigella flexneri 2a str. 2457T], gi\|30041419\|gb\|AAP17147... gi\|188013803, gi... - gi\|188013803\|gb\|EDU51925.1\| lactoylglutathione lyase [Escherichia coli O157:H7 str. EC4113], gi\|1687... gi\|15802065, gi\|... - gi\|15802065\|ref\|NP_288087.1\| glyoxalase I [Escherichia coli O157:H7 EDL933], gi\|12515646\|gb\|AAG56640... gi\|189354302, gi... - gi\|189354302\|gb\|EDU72721.1\| lactoylglutathione lyase [Escherichia coli O157:H7 str. EC4401], gi\|1687... EG13421 - glyoxalase I, Ni-dependent / Glyoxalase I, lactoylglutathione lyase, Ni(2+) cofactor; inactivated by... gi\|168765302, gi... - gi\|189364909\|gb\|EDU83325.1\| lactoylglutathione lyase [Escherichia coli O157:H7 str. EC4501], gi\|1687... EG13421 - glyoxalase I, Ni-dependent / Glyoxalase I, lactoylglutathione lyase, Ni(2+) cofactor; inactivated by... gi\|168771195, gi... - gi\|189360032\|gb\|EDU78451.1\| lactoylglutathione lyase [Escherichia coli O157:H7 str. EC4486], gi\|1687... gi\|187768661, gi... - gi\|187768661\|gb\|EDU32505.1\| lactoylglutathione lyase [Escherichia coli O157:H7 str. EC4196], gi\|1687... gi\|208816874, gi... - gi\|208816874\|ref\|ZP_03257994.1\| lactoylglutathione lyase [Escherichia coli O157:H7 str. EC4045], gi\|... gi\|209161242, gi... - gi\|209399842\|ref\|YP_002270720.1\| lactoylglutathione lyase [Escherichia coli O157:H7 str. EC4115], gi... gi\|209918965, gi... - gi\|209918965\|ref\|YP_002293049.1\| glyoxalase I [Escherichia coli SE11], gi\|209912224\|dbj\|BAG77298.1\| ... gi\|215264900, gi... - gi\|215486828\|ref\|YP_002329259.1\| glyoxalase I [Escherichia coli O127:H6 str. E2348/69], gi\|215264900... gi\|15831614, gi\|... - gi\|15831614\|ref\|NP_310387.1\| glyoxalase I [Escherichia coli O157:H7 str. Sakai], gi\|13361827\|dbj\|BAB... gi\|217328788, gi... - gi\|217328788\|ref\|ZP_03444869.1\| lactoylglutathione lyase [Escherichia coli O157:H7 str. TW14588], gi... gi\|110805627, gi... - gi\|110805627\|ref\|YP_689147.1\| glyoxalase I [Shigella flexneri 5 str. 8401], gi\|110615175\|gb\|ABF03842... gi\|218356295, gi... - gi\|218548754\|ref\|YP_002382545.1\| glyoxalase I [Escherichia fergusonii ATCC 35469], gi\|218356295\|emb\|... gi\|218351946, gi... - gi\|218695214\|ref\|YP_002402881.1\| glyoxalase I [Escherichia coli 55989], gi\|218351946\|emb\|CAU97678.1\|... gi\|218699781, gi... - gi\|218699781\|ref\|YP_002407410.1\| glyoxalase I [Escherichia coli IAI39], gi\|218369767\|emb\|CAR17538.1\|... gi\|188998796, gi... - gi\|188998796\|gb\|EDU67782.1\| lactoylglutathione lyase [Escherichia coli O157:H7 str. EC4076], gi\|1687... gi\|168789490, gi... - gi\|189370975\|gb\|EDU89391.1\| lactoylglutathione lyase [Escherichia coli O157:H7 str. EC869], gi\|16878... gi\|85675062, gi\|... - gi\|89108493\|ref\|AP_002273.1\| glyoxalase I, Ni-dependent [Escherichia coli str. K-12 substr. W3110], ... gi\|124531618, gi... - gi\|124531618\|ref\|ZP_01701829.1\| lactoylglutathione lyase [Escherichia coli B], gi\|124498473\|gb\|EAY45... gi\|189375326, gi... - gi\|189375326\|gb\|EDU93742.1\| lactoylglutathione lyase [Escherichia coli O157:H7 str. EC508], gi\|16880... gi\|169754925, gi... - gi\|170019997\|ref\|YP_001724951.1\| glyoxalase I [Escherichia coli ATCC 8739], gi\|169754925\|gb\|ACA77624... gi\|169889149, gi... - gi\|170081314\|ref\|YP_001730634.1\| glyoxalase I, Ni-dependent [Escherichia coli str. K-12 substr. DH10... gi\|170517974, gi... - gi\|170680256\|ref\|YP_001743602.1\| lactoylglutathione lyase [Escherichia coli SMS-3-5], gi\|170517974\|g... gi\|254592668, gi... - gi\|254793268\|ref\|YP_003078105.1\| glyoxalase I, Ni-dependent [Escherichia coli O157:H7 str. TW14359],... gi\|195940214 - gi\|195940214\|ref\|ZP_03085596.1\| glyoxalase I [Escherichia coli O157:H7 str. EC4024] gi\|254161713, gi... - gi\|254161713\|ref\|YP_003044821.1\| glyoxalase I, Ni-dependent [Escherichia coli B str. REL606], gi\|253... gi\|208810408, gi... - gi\|208810408\|ref\|ZP_03252284.1\| lactoylglutathione lyase [Escherichia coli O157:H7 str. EC4206], gi\|... gi\|253773390, gi... - gi\|254288502\|ref\|YP_003054250.1\| glyoxalase I, Ni-dependent [Escherichia coli BL21(DE3)], gi\|2539778... gi\|194415941, gi... - gi\|75212987\|ref\|ZP_00712985.1\| COG0346: Lactoylglutathione lyase and related lyases [Escherichia col... gi\|251785108, gi... - gi\|251785108\|ref\|YP_002999412.1\| hypothetical protein B21_01611 [Escherichia coli BL21], gi\|24237738... gi\|190904046, gi... - gi\|75230901\|ref\|ZP_00717350.1\| COG0346: Lactoylglutathione lyase and related lyases [Escherichia col... gi\|238900867, gi... - gi\|238900867\|ref\|YP_002926663.1\| glyoxalase I, Ni-dependent [Escherichia coli BW2952], gi\|238861381\|... gi\|194436567, gi... - gi\|83587985\|ref\|ZP_00926611.1\| COG0346: Lactoylglutathione lyase and related lyases [Escherichia col... gi\|75195730, gi\|... - gi\|75195730\|ref\|ZP_00705800.1\| COG0346: Lactoylglutathione lyase and related lyases [Escherichia col... gi\|73855498, gi\|... - gi\|74312021\|ref\|YP_310440.1\| glyoxalase I [Shigella sonnei Ss046], gi\|73855498\|gb\|AAZ88205.1\| lactoy... LGUL_ECOLI - Lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase) (Aldoketomutase) (Glyoxalase I) (Glx I) (Ke... gi\|81241276, gi\|... - gi\|82777128\|ref\|YP_403477.1\| glyoxalase I [Shigella dysenteriae Sd197], gi\|81241276\|gb\|ABB61986.1\| l... gi\|193070231, gi... - gi\|75234962\|ref\|ZP_00719241.1\| COG0346: Lactoylglutathione lyase and related lyases [Escherichia col... gi\|193064933, gi... - gi\|75257069\|ref\|ZP_00728629.1\| COG0346: Lactoylglutathione lyase and related lyases [Escherichia col... gi\|218432248, gi... - gi\|218705151\|ref\|YP_002412670.1\| glyoxalase I [Escherichia coli UMN026], gi\|218432248\|emb\|CAR13138.1...	3.0E-33	[1..135]	[1..135]
gi\|157080414, gi... - gi\|75190690\|ref\|ZP_00703957.1\| COG0346: Lactoylglutathione lyase and related lyases [Escherichia col...	3.0E-33	[1..135]	[1..135]
gi\|110343365, gi... - gi\|110641773\|ref\|YP_669503.1\| glyoxalase I [Escherichia coli 536], gi\|110343365\|gb\|ABG69602.1\| lacto... gi\|117623835, gi... - gi\|117623835\|ref\|YP_852748.1\| glyoxalase I [Escherichia coli APEC O1], gi\|115512959\|gb\|ABJ01034.1\| l... gi\|227837110, gi... - gi\|227885931\|ref\|ZP_04003736.1\| Lactoylglutathione lyase [Escherichia coli 83972], gi\|227837110\|gb\|E... gi\|237705596, gi... - gi\|237705596\|ref\|ZP_04536077.1\| lactoylglutathione lyase [Escherichia sp. 3_2_53FAA], gi\|226900353\|g... gi\|75238789, gi\|... - gi\|75238789\|ref\|ZP_00722773.1\| COG0346: Lactoylglutathione lyase and related lyases [Escherichia col... gi\|91210865, gi\|... - gi\|91210865\|ref\|YP_540851.1\| glyoxalase I [Escherichia coli UTI89], gi\|91072439\|gb\|ABE07320.1\| lacto... gi\|26108302, gi\|... - gi\|26247899\|ref\|NP_753939.1\| glyoxalase I [Escherichia coli CFT073], gi\|26108302\|gb\|AAN80504.1\|AE016... gi\|194434721, gi... - gi\|194434721\|ref\|ZP_03066974.1\| lactoylglutathione lyase [Shigella dysenteriae 1012], gi\|194417059\|g... gi\|170768683, gi... - gi\|170768683\|ref\|ZP_02903136.1\| lactoylglutathione lyase [Escherichia albertii TW07627], gi\|17012223... gi\|218427161, gi... - gi\|218689597\|ref\|YP_002397809.1\| glyoxalase I [Escherichia coli ED1a], gi\|218427161\|emb\|CAR08044.2\| ... gi\|218365291, gi... - gi\|218558522\|ref\|YP_002391435.1\| glyoxalase I [Escherichia coli S88], gi\|218365291\|emb\|CAR03012.1\| g...	3.0E-33	[1..135]	[1..135]
gi\|187731273, gi... - gi\|75178453\|ref\|ZP_00698499.1\| COG0346: Lactoylglutathione lyase and related lyases [Shigella boydii... gi\|81245394, gi\|... - gi\|82543983\|ref\|YP_407930.1\| glyoxalase I [Shigella boydii Sb227], gi\|81245394\|gb\|ABB66102.1\| lactoy...	6.0E-33	[1..135]	[1..135]
gi\|7467271, gi\|1... - pir\|\|JC6313 lactoylglutathione lyase (EC 4.4.1.5) [validated] - Salmonella typhimurium, gi\|1354847\|g... gi\|1354847\|gb\|AA... - S-D-lactolyglutathione methylglyoxal lyase	7.0E-33	[1..135]	[1..135]
gi\|227081184, gi... - gi\|227081184\|ref\|YP_002809735.1\| lactoylglutathione lyase [Vibrio cholerae M66-2], gi\|227009072\|gb\|A... gi\|153829533, gi... - gi\|153829533\|ref\|ZP_01982200.1\| lactoylglutathione lyase [Vibrio cholerae 623-39], gi\|148874993\|gb\|E... gi\|229350904, gi... - gi\|229510939\|ref\|ZP_04400418.1\| lactoylglutathione lyase [Vibrio cholerae B33], gi\|229350904\|gb\|EEO1... gi\|229515396, gi... - gi\|229515396\|ref\|ZP_04404855.1\| lactoylglutathione lyase [Vibrio cholerae TMA 21], gi\|229347165\|gb\|E... gi\|9655474, gi\|1... - gi\|9655474\|gb\|AAF94171.1\| lactoylglutathione lyase [Vibrio cholerae O1 biovar El Tor str. N16961], g... gi\|227012827, gi... - gi\|227117377\|ref\|YP_002819273.1\| lactoylglutathione lyase [Vibrio cholerae O395], gi\|227012827\|gb\|AC... gi\|229357614, gi... - gi\|229505391\|ref\|ZP_04394901.1\| lactoylglutathione lyase [Vibrio cholerae BX 330286], gi\|229357614\|g... gi\|254843845, gi... - gi\|254848140\|ref\|ZP_05237490.1\| lactoylglutathione lyase [Vibrio cholerae MO10], gi\|254843845\|gb\|EET... gi\|229344775, gi... - gi\|229518060\|ref\|ZP_04407504.1\| lactoylglutathione lyase [Vibrio cholerae RC9], gi\|229344775\|gb\|EEO0... gi\|121628268, gi... - gi\|121729982\|ref\|ZP_01682399.1\| lactoylglutathione lyase [Vibrio cholerae V52], gi\|121628268\|gb\|EAX6... gi\|229371065, gi... - gi\|229608410\|ref\|YP_002879058.1\| lactoylglutathione lyase [Vibrio cholerae MJ-1236], gi\|229371065\|gb... LGUL_VIBCH - (Q9KT93) Probable lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase) (Aldoketomutase) (Glyoxal...	8.0E-33	[2..133]	[51..182]
gi\|53763628, gi\|... - gi\|75906364\|ref\|YP_320660.1\| glyoxalase I [Anabaena variabilis ATCC 29413], gi\|75700089\|gb\|ABA19765....	8.0E-33	[1..133]	[1..133]
gi\|25529923 - pir\|\|AB2096 lactoylglutathione lyase [imported] - Nostoc sp. (strain PCC 7120) gi\|17229813, gi\|... - gi\|17229813\|ref\|NP_486361.1\| lactoylglutathione lyase [Nostoc sp. PCC 7120], gi\|17131413\|dbj\|BAB7402...	8.0E-33	[1..133]	[1..133]
gi\|186466114, gi... - gi\|23128141\|ref\|ZP_00109995.1\| COG0346: Lactoylglutathione lyase and related lyases [Nostoc punctifo...	9.0E-33	[1..133]	[1..133]
gi\|15602852, gi\|... - gi\|15602852\|ref\|NP_245924.1\| hypothetical protein PM0987 [Pasteurella multocida subsp. multocida str... tr\|J6CVB7\|J6CVB7... - Lactoylglutathione lyase OS=Pasteurella multocida subsp. multocida str. Anand1_cattle GN=AAUPMC_1045...	1.0E-32	[1..135]	[1..135]

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Predicted Domain #1

Region A:
Residues: [1-135]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLLHTMLRV GDLQRSIAFY TNVLGMKLLR TSENPEYKYS LAFVGYGPET EEAVIELTYN  60
   61 WGVESYDMGN AYGHIALSVD NAAEACERIR QNGGNVTREA GPVKGGSTII AFVEDPDGYK 120
  121 IELIEAKDAG RGLGN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	34.69897
Match:	1f9zA
Description:	Glyoxalase I (lactoylglutathione lyase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
lactoylglutathione lyase activity	3.91334658149719	bayes_pls_golite062009
carbon-sulfur lyase activity	1.44168339433372	bayes_pls_golite062009
catalytic activity	1.21778090213032	bayes_pls_golite062009
binding	0.78394104122898	bayes_pls_golite062009
protein binding	0.0335467332601391	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: