YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|227175800, gi...
Organism:	Enterococcus faecalis HH22
Length:	226 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|227175800, gi....

Description	E-value	Query Range	Subject Range
UNG_AZOVD - Uracil-DNA glycosylase OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=ung PE=3 SV=1 gi\|53611343, gi\|... - gi\|67153345\|ref\|ZP_00415090.1\| Uracil-DNA glycosylase [Azotobacter vinelandii AvOP], ref\|ZP_00090188...	379.0	[0..5]	[225..10]
gi\|95112272 - gi\|95112272\|emb\|CAK16999.1\| uracil-DNA glycosylase [Pseudomonas entomophila L48] UNG_PSEE4 - Uracil-DNA glycosylase OS=Pseudomonas entomophila (strain L48) GN=ung PE=3 SV=1	373.0	[0..2]	[224..6]
UNG_PSEPK - Uracil-DNA glycosylase OS=Pseudomonas putida (strain KT2440) GN=ung PE=3 SV=1	373.0	[0..2]	[224..6]
gi\|82739988, gi\|... - gi\|82739988\|ref\|ZP_00902762.1\| Uracil-DNA glycosylase [Pseudomonas putida F1], gi\|82712950\|gb\|EAP480...	372.0	[0..2]	[224..52]
gi\|110834507, gi... - gi\|110834507\|ref\|YP_693366.1\| uracil-DNA glycosylase [Alcanivorax borkumensis SK2], gi\|110647618\|emb...	372.0	[0..5]	[224..17]
gi\|68196051, gi\|... - gi\|69245050\|ref\|ZP_00603208.1\| Uracil-DNA glycosylase [Enterococcus faecium DO], gi\|68196051\|gb\|EAN1...	371.0	[0..1]	[226..1]
UNG_PSEPF - Uracil-DNA glycosylase OS=Pseudomonas fluorescens (strain Pf0-1) GN=ung PE=3 SV=1	371.0	[0..2]	[226..6]
UNG_PSEF5 - Uracil-DNA glycosylase OS=Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) GN=ung PE=3 SV=1	370.0	[0..2]	[224..6]
UNG_PSEAE - Uracil-DNA glycosylase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 1222... UNG_PSEA7 - Uracil-DNA glycosylase OS=Pseudomonas aeruginosa (strain PA7) GN=ung PE=3 SV=1 gi\|107100210 - gi\|107100210\|ref\|ZP_01364128.1\| hypothetical protein PaerPA_01001233 [Pseudomonas aeruginosa PACS2] gi\|254239113, gi... - gi\|84316793\|ref\|ZP_00965258.1\| COG0692: Uracil DNA glycosylase [Pseudomonas aeruginosa C3719], gi\|25... UNG_PSEAE - Uracil-DNA glycosylase OS=Pseudomonas aeruginosa GN=ung PE=3 SV=1 gi\|126198383, gi... - gi\|84322821\|ref\|ZP_00970902.1\| COG0692: Uracil DNA glycosylase [Pseudomonas aeruginosa 2192], gi\|254... UNG_PSEA8 - Uracil-DNA glycosylase OS=Pseudomonas aeruginosa (strain LESB58) GN=ung PE=3 SV=1	370.0	[0..2]	[224..7]
UNG_PSEAB - Uracil-DNA glycosylase OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=ung PE=3 SV=1	369.0	[0..2]	[224..7]

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Predicted Domain #1

Region A:
Residues: [1-226]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKEIIHNSWQ NILSAEFEKP YYQELREFLK KEYQTQTIYP DMYHLFSALE LTPFEEVKVV  60
   61 ILGQDPYHGP NQAHGLSFSV QPGVKVPPSL ANIYKELQAD LGYQPVNHGF LESWAKQGVL 120
  121 LLNTVLTVRA GQAYSHRGKG WEQLTDVIIE KLNEREKPVV FILWGRPAQE KIKMIDTTRH 180
  181 VIIKSPHPSP LSAHRGFFGS RPFSQANAAL ERLGETPIDW QLPETV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	100.0
Match:	1eugA
Description:	Uracil-DNA glycosylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
DNA N-glycosylase activity	4.32235853064174	bayes_pls_golite062009
uracil DNA N-glycosylase activity	4.14707882788321	bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds	3.89636585289546	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	2.84444466513934	bayes_pls_golite062009
hydrolase activity	1.91716804176625	bayes_pls_golite062009
single-strand selective uracil DNA N-glycosylase activity	1.65657095637032	bayes_pls_golite062009
catalytic activity	1.59111295908728	bayes_pls_golite062009
mismatch base pair DNA N-glycosylase activity	0.783383667044285	bayes_pls_golite062009
binding	0.587736812286194	bayes_pls_golite062009
structure-specific DNA binding	0.381118322219236	bayes_pls_golite062009
protein binding	0.272261244770552	bayes_pls_golite062009
nucleic acid binding	0.0311777202379154	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: