YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|229357614, gi...
Organism:	Vibrio cholerae BX 330286
Length:	184 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|229357614, gi....

Description	E-value	Query Range	Subject Range
gi\|75829851, gi\|... - gi\|75829851\|ref\|ZP_00759141.1\| COG0346: Lactoylglutathione lyase and related lyases [Vibrio cholerae... LGUL_VIBCH - Probable lactoylglutathione lyase OS=Vibrio cholerae GN=gloA PE=3 SV=2 gi\|75814530 - gi\|75814530\|ref\|ZP_00745106.1\| COG0346: Lactoylglutathione lyase and related lyases [Vibrio cholerae... gi\|146316487, gi... - gi\|75826317\|ref\|ZP_00755752.1\| COG0346: Lactoylglutathione lyase and related lyases [Vibrio cholerae... gi\|153820545, gi... - gi\|153820545\|ref\|ZP_01973212.1\| lactoylglutathione lyase [Vibrio cholerae NCTC 8457], gi\|126508912\|g... gi\|229525623, gi... - gi\|229525623\|ref\|ZP_04415028.1\| lactoylglutathione lyase [Vibrio cholerae bv. albensis VL426], gi\|22... LGUL_VIBCH - Probable lactoylglutathione lyase OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N...	143.0	[0..47]	[184..1]
gi\|91187534, gi\|... - gi\|91228903\|ref\|ZP_01262803.1\| lactoylglutathione lyase [Vibrio alginolyticus 12G01], gi\|91187534\|gb...	141.0	[0..51]	[184..5]
gi\|37198112, gi\|... - gi\|37679369\|ref\|NP_933978.1\| lactoylglutathione lyase [Vibrio vulnificus YJ016], gi\|37198112\|dbj\|BAC...	139.0	[0..51]	[184..5]
LGUL_VIBPA - Probable lactoylglutathione lyase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN... LGUL_VIBPA - Probable lactoylglutathione lyase OS=Vibrio parahaemolyticus GN=gloA PE=3 SV=2	137.0	[0..51]	[184..5]
gi\|497131 - gi\|497131\|gb\|AAA21576.1\| ORF1	136.0	[0..52]	[184..1]
gi\|71669193, gi\|... - gi\|71677562\|ref\|ZP_00675298.1\| Glyoxalase I [Trichodesmium erythraeum IMS101], gi\|71669193\|gb\|EAO258...	136.0	[0..50]	[183..1]
gi\|218708966, gi... - gi\|218708966\|ref\|YP_002416587.1\| Probable lactoylglutathione lyase [Vibrio splendidus LGP32], gi\|218... gi\|84376010, gi\|... - gi\|84393401\|ref\|ZP_00992160.1\| lactoylglutathione lyase [Vibrio splendidus 12B01], gi\|84376010\|gb\|EA... gi\|86147966, gi\|... - gi\|86147966\|ref\|ZP_01066270.1\| lactoylglutathione lyase [Vibrio sp. MED222], gi\|85834291\|gb\|EAQ52445...	135.0	[0..51]	[184..5]
LGUC_ARATH - Probable lactoylglutathione lyase, chloroplastic OS=Arabidopsis thaliana GN=At1g67280 PE=1 SV=1	135.0	[0..1]	[183..163]
gi\|197335824, gi... - gi\|197335824\|ref\|YP_002155691.1\| lactoylglutathione lyase [Vibrio fischeri MJ11], gi\|197317314\|gb\|AC... gi\|59711535, gi\|... - gi\|59711535\|ref\|YP_204311.1\| glyoxalase I, Ni-dependent [Vibrio fischeri ES114], gi\|59479636\|gb\|AAW8...	135.0	[0..51]	[184..5]

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Predicted Domain #1

Region A:
Residues: [1-184]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVTPVSRAN HVVAVALSKI FVNSKIKCTQ KANFPKNRYP ESKELLMSNH RILHTMLRVG  60
   61 DLDKSIEFYT QVMGMSLLRK NENTEYKYTL AFLGYGDESQ GAVIELTYNW GVADYEKGNA 120
  121 YGHIAIGVDD IYATCDTIKA AGGIVTREPG PVKGGTTHIA FVKDPDGYMI ELIQNKQAHA 180
  181 GLEG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.522879
Match:	1f9zA
Description:	Glyoxalase I (lactoylglutathione lyase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
lactoylglutathione lyase activity	3.91334658149719	bayes_pls_golite062009
carbon-sulfur lyase activity	1.44168339433372	bayes_pls_golite062009
catalytic activity	1.21778090213032	bayes_pls_golite062009
binding	1.0454158969791	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	0.397354910065381	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	0.343093696737896	bayes_pls_golite062009
protein binding	0.28912087714501	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: