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View Structure Prediction Details

Protein: gi|238829172, gi...
Organism: Enterococcus faecalis TUSoD Ef11
Length: 273 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|238829172, gi....

Description E-value Query
Range
Subject
Range
gi|293572666|ref... - pur operon repressor [Enterococcus faecium E980]
gi|48825658 - ref|ZP_00286899.1| COG0503: Adenine/guanine phosphoribosyltransferases and related PRPP-binding prot...
gi|227552700, gi... - gi|227552700|ref|ZP_03982749.1| purine operon repressor [Enterococcus faecium TX1330], gi|227178163|...
gi|69245414, gi|... - gi|69245414|ref|ZP_00603409.1| Pur operon repressor [Enterococcus faecium DO], gi|68195796|gb|EAN102...
233.0 [0..1] [272..1]
gi|34809639, gi|... - gi|34809640|pdb|1O57|D Chain D, Crystal Structure Of The Purine Operon Repressor Of Bacillus Subtili...
230.0 [0..1] [270..1]
PURR_BACSU - Pur operon repressor OS=Bacillus subtilis GN=purR PE=1 SV=1
gi|221321374 - gi|221321374|ref|ZP_03602668.1| purine operon repressor [Bacillus subtilis subsp. subtilis str. SMY]
gi|221312178 - gi|221312178|ref|ZP_03593983.1| purine operon repressor [Bacillus subtilis subsp. subtilis str. NCIB...
PURR_BACSU - Pur operon repressor OS=Bacillus subtilis (strain 168) GN=purR PE=1 SV=1
gi|221317111 - gi|221317111|ref|ZP_03598405.1| purine operon repressor [Bacillus subtilis subsp. subtilis str. JH64...
230.0 [0..1] [270..1]
gi|16799308 - gi|16799308|ref|NP_469576.1| purine operon repressor [Listeria innocua Clip11262]
gi|16412650, gi|... - pir||AH1461 PurR, transcription repressor of purine operon of B. subtilis homolog lin0231 [imported]...
226.0 [0..1] [271..1]
gi|224503488 - gi|224503488|ref|ZP_03671795.1| purine operon repressor [Listeria monocytogenes FSL R2-561]
gi|224500355 - gi|224500355|ref|ZP_03668704.1| purine operon repressor [Listeria monocytogenes Finland 1988]
gi|47096185, gi|... - gi|47096185|ref|ZP_00233784.1| Pur operon transcriptional repressor [Listeria monocytogenes str. 1/2...
gi|16802238 - gi|16802238|ref|NP_463723.1| purine operon repressor [Listeria monocytogenes EGD-e]
gi|16409549, gi|... - pir||AI1098 PurR, transcription repressor of purine operon of B. subtilis homolog lmo0192 [imported]...
gi|47092875, gi|... - gi|47092875|ref|ZP_00230658.1| Pur operon transcriptional repressor [Listeria monocytogenes str. 4b ...
gi|46906424, gi|... - gi|46906424|ref|YP_012813.1| purine operon repressor [Listeria monocytogenes str. 4b F2365], gi|4687...
gi|116871581, gi... - gi|116871581|ref|YP_848362.1| purine operon repressor [Listeria welshimeri serovar 6b str. SLCC5334]...
gi|254901023, gi... - gi|254901023|ref|ZP_05260947.1| pur operon repressor [Listeria monocytogenes J0161], gi|153186186|re...
gi|153198201, gi... - gi|254832488|ref|ZP_05237143.1| pur operon repressor [Listeria monocytogenes 10403S], gi|153198201|r...
gi|254913909, gi... - gi|254913909|ref|ZP_05263921.1| pur operon repressor [Listeria monocytogenes J2818], gi|153189359|re...
gi|153165156, gi... - gi|254871774|ref|ZP_05244484.1| pur operon repressor [Listeria monocytogenes FSL N1-017], gi|1531651...
gi|225875283, gi... - gi|226222821|ref|YP_002756928.1| PurR, transcription repressor of purine operon of B. subtilis [List...
gi|254829283, gi... - gi|254829283|ref|ZP_05233970.1| pur operon repressor [Listeria monocytogenes FSL N3-165], gi|1531728...
gi|254825895 - gi|254825895|ref|ZP_05230896.1| pur operon repressor [Listeria monocytogenes FSL J1-194]
gi|133733923, gi... - gi|254938300|ref|ZP_05269997.1| pur operon repressor [Listeria monocytogenes F6900], gi|153177848|re...
gi|254879109 - gi|254879109|ref|ZP_05251819.1| pur operon repressor [Listeria monocytogenes FSL J2-071]
gi|153200628, gi... - gi|254933031|ref|ZP_05266390.1| pur operon repressor [Listeria monocytogenes HPB2262], gi|153200628|...
gi|254992656 - gi|254992656|ref|ZP_05274846.1| pur operon repressor [Listeria monocytogenes FSL J2-064]
gi|255029034 - gi|255029034|ref|ZP_05300985.1| pur operon repressor [Listeria monocytogenes LO28]
gi|255519701 - gi|255519701|ref|ZP_05386938.1| pur operon repressor [Listeria monocytogenes FSL J1-175]
226.0 [0..1] [271..1]
gi|52346406, gi|... - gi|52783904|ref|YP_089733.1| purine operon repressor [Bacillus licheniformis ATCC 14580], gi|5234640...
224.0 [0..1] [269..1]
gi|42735040, gi|... - gi|42779125|ref|NP_976372.1| purine operon repressor [Bacillus cereus ATCC 10987], gi|42735040|gb|AA...
221.0 [0..1] [269..1]
gi|228937349, gi... - gi|228937349|ref|ZP_04099996.1| Pur operon repressor [Bacillus thuringiensis serovar berliner ATCC 1...
gi|228898800, gi... - gi|228898800|ref|ZP_04063083.1| Pur operon repressor [Bacillus thuringiensis IBL 4222], gi|228860825...
gi|228976805, gi... - gi|228976805|ref|ZP_04137218.1| Pur operon repressor [Bacillus thuringiensis Bt407], gi|228782901|gb...
gi|74492899, gi|... - gi|75759608|ref|ZP_00739694.1| Pur operon repressor [Bacillus thuringiensis serovar israelensis ATCC...
gi|228970235, gi... - gi|228970235|ref|ZP_04130895.1| Pur operon repressor [Bacillus thuringiensis serovar thuringiensis s...
gi|218544270, gi... - gi|218895182|ref|YP_002443593.1| pur operon repressor [Bacillus cereus G9842], gi|218544270|gb|ACK96...
220.0 [0..1] [269..1]
gi|29893857, gi|... - gi|30018317|ref|NP_829948.1| purine operon repressor [Bacillus cereus ATCC 14579], gi|29893857|gb|AA...
220.0 [0..1] [269..1]
gi|21398009, gi|... - gi|65317506|ref|ZP_00390465.1| COG0503: Adenine/guanine phosphoribosyltransferases and related PRPP-...
gi|30260236, gi|... - gi|30260236|ref|NP_842613.1| purine operon repressor [Bacillus anthracis str. Ames], gi|30253557|gb|...
gi|254762411 - gi|254762411|ref|ZP_05214253.1| pur operon repressor [Bacillus anthracis str. Australia 94]
gi|254756355 - gi|254756355|ref|ZP_05208384.1| pur operon repressor [Bacillus anthracis str. Vollum]
gi|254744650 - gi|254744650|ref|ZP_05202329.1| pur operon repressor [Bacillus anthracis str. Kruger B]
gi|254733603 - gi|254733603|ref|ZP_05191322.1| pur operon repressor [Bacillus anthracis str. Western North America ...
gi|254724187 - gi|254724187|ref|ZP_05185972.1| pur operon repressor [Bacillus anthracis str. A1055]
gi|254682327 - gi|254682327|ref|ZP_05146188.1| pur operon repressor [Bacillus anthracis str. CNEVA-9066]
gi|229266284, gi... - gi|229601876|ref|YP_002864697.1| pur operon repressor [Bacillus anthracis str. A0248], gi|229266284|...
gi|227812719, gi... - gi|227812719|ref|YP_002812728.1| pur operon repressor [Bacillus anthracis str. CDC 684], gi|22700643...
gi|225790390, gi... - gi|225862098|ref|YP_002747476.1| pur operon repressor [Bacillus cereus 03BB102], gi|225790390|gb|ACO...
gi|51978639, gi|... - gi|52145170|ref|YP_081658.1| purine operon repressor [Bacillus cereus E33L], gi|51978639|gb|AAU20189...
gi|47525299, gi|... - gi|47525299|ref|YP_016648.1| purine operon repressor [Bacillus anthracis str. 'Ames Ancestor'], gi|4...
gi|49177007, gi|... - gi|49183080|ref|YP_026332.1| purine operon repressor [Bacillus anthracis str. Sterne], gi|49177007|g...
gi|167529516, gi... - gi|167635042|ref|ZP_02393359.1| pur operon repressor [Bacillus anthracis str. A0442], gi|167529516|g...
gi|167510529, gi... - gi|167641544|ref|ZP_02399792.1| pur operon repressor [Bacillus anthracis str. A0193], gi|167510529|g...
gi|170667152, gi... - gi|170688928|ref|ZP_02880130.1| pur operon repressor [Bacillus anthracis str. A0465], gi|170667152|g...
gi|170127513, gi... - gi|170707517|ref|ZP_02897970.1| pur operon repressor [Bacillus anthracis str. A0389], gi|170127513|g...
gi|172080167, gi... - gi|177655326|ref|ZP_02936855.1| pur operon repressor [Bacillus anthracis str. A0174], gi|172080167|g...
gi|190569006, gi... - gi|190569006|ref|ZP_03021907.1| pur operon repressor [Bacillus anthracis Tsiankovskii-I], gi|1905599...
gi|196036390, gi... - gi|196036390|ref|ZP_03103787.1| pur operon repressor [Bacillus cereus W], gi|195991020|gb|EDX54991.1...
gi|196041759, gi... - gi|196041759|ref|ZP_03109049.1| pur operon repressor [Bacillus cereus NVH0597-99], gi|196027379|gb|E...
gi|164711682, gi... - gi|165872554|ref|ZP_02217186.1| pur operon repressor [Bacillus anthracis str. A0488], gi|164711682|g...
gi|196047388, gi... - gi|196047388|ref|ZP_03114601.1| pur operon repressor [Bacillus cereus 03BB108], gi|196021790|gb|EDX6...
gi|118415042, gi... - gi|118475817|ref|YP_892968.1| pur operon repressor [Bacillus thuringiensis str. Al Hakam], gi|118415...
219.0 [0..1] [269..1]

Back

Predicted Domain #1
Region A:
Residues: [1-273]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIRRSERLI DMTQYLLDHP HTLVSLTYFA DRYQSAKSSI SEDLAIVKKT FKERGTGILE  60
   61 TIPGAAGGVR FIPEIPYEEA EQLIMDLCDR LSEQDRLLPG GYVYLSDLLG EPNLLRQVGR 120
  121 IIASKYLGKQ IDAVMTVATK GVPIAQAVSY YLNVPFVIVR RDSKITEGST VSVNYVSGSS 180
  181 ERIEKMELSK RSLKRGSKVL VVDDFMKGGG TVNGMKSMIE EFEAELVGIT VFAESKFNGR 240
  241 RAIDDYTSLL YVEDVDTQTK TISVVPGNYF TEK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 60.522879
Match: 1p4aA
Description: Crystal Structure of the PurR complexed with cPRPP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transcription regulator activity 3.98990675336286 bayes_pls_golite062009
DNA binding 3.4273272886116 bayes_pls_golite062009
nucleic acid binding 3.38054693035398 bayes_pls_golite062009
transferase activity, transferring pentosyl groups 3.03016109611914 bayes_pls_golite062009
transcription factor activity 2.80110428028438 bayes_pls_golite062009
uracil phosphoribosyltransferase activity 2.54772263155456 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 2.53464204724265 bayes_pls_golite062009
binding 2.18911933843505 bayes_pls_golite062009
amidophosphoribosyltransferase activity 1.87184614964143 bayes_pls_golite062009
ribose phosphate diphosphokinase activity 1.7212298503296 bayes_pls_golite062009
diphosphotransferase activity 1.16607700772697 bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity 0.824877195846631 bayes_pls_golite062009
transcription activator activity 0.53294679084865 bayes_pls_golite062009
sequence-specific DNA binding 0.53285802828572 bayes_pls_golite062009
transcription repressor activity 0.513853050429619 bayes_pls_golite062009
adenine phosphoribosyltransferase activity 0.46065288387965 bayes_pls_golite062009
protein binding 0.035220363090062 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle