YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|227546197, gi...
Organism:	Bifidobacterium longum subsp. longum ATCC 55813
Length:	261 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|227546197, gi....

Description	E-value	Query Range	Subject Range
gi\|46191084 - gi\|46191084\|ref\|ZP_00206668.1\| COG1057: Nicotinic acid mononucleotide adenylyltransferase [Bifidobac...	1.0E-64	[20..261]	[1..242]
gi\|6714685, gi\|2... - gi\|6714685\|emb\|CAB66257.1\| putative nicotinate-nucleotide adenylyltransferase [Streptomyces coelicol...	6.0E-60	[9..260]	[7..238]
gi\|29609139, gi\|... - gi\|29832021\|ref\|NP_826655.1\| nicotinic acid mononucleotide adenylyltransferase [Streptomyces avermit...	4.0E-55	[44..260]	[8..224]
gi\|85667579 - gi\|85667579\|ref\|ZP_01029796.1\| hypothetical protein Badol_01000066 [Bifidobacterium adolescentis]	1.0E-54	[10..258]	[2..248]
NADD_COREF - Probable nicotinate-nucleotide adenylyltransferase OS=Corynebacterium efficiens (strain DSM 44549 / ... NADD_COREF - Probable nicotinate-nucleotide adenylyltransferase OS=Corynebacterium efficiens GN=nadD PE=3 SV=2	2.0E-53	[61..260]	[4..205]
gi\|25028813, gi\|... - gi\|25028813\|ref\|NP_738867.1\| nicotinic acid mononucleotide adenylyltransferase [Corynebacterium effi...	4.0E-53	[61..260]	[19..220]
gi\|21325123, gi\|... - gi\|62391195\|ref\|YP_226597.1\| nicotinic acid mononucleotide adenylyltransferase [Corynebacterium glut...	7.0E-52	[56..260]	[2..212]
gi\|227867505, gi... - gi\|227890567\|ref\|ZP_04008372.1\| nicotinate-nucleotide adenylyltransferase [Lactobacillus salivarius ... gi\|90820672, gi\|... - gi\|90961478\|ref\|YP_535394.1\| nicotinate-nucleotide adenylyltransferase [Lactobacillus salivarius UCC...	2.0E-51	[59..259]	[15..210]
gi\|48825491 - ref\|ZP_00286739.1\| COG1057: Nicotinic acid mononucleotide adenylyltransferase [Enterococcus faecium] gi\|69245738, gi\|... - gi\|69245738\|ref\|ZP_00603604.1\| Cytidyltransferase-related:Probable nicotinate-nucleotide adenylyltra... gi\|293571010\|ref... - nicotinate (nicotinamide) nucleotide adenylyltransferase [Enterococcus faecium E980]	3.0E-51	[64..259]	[24..214]

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Predicted Domain #1

Region A:
Residues: [1-261]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGVTDSHKT AASVQSEKSV ESAEPAEIVA VTQGETERRM SDLSAPAGAS SHGKGRLSAR  60
   61 GNWHTRLRVG IMGGTFDPIH NGHLVAASEV AWVYDLDEVI FVPTGRPVFK LDKHVTNAED 120
  121 RYLMTVIATA SNPKFTVSRV DIDRPGVTYT IDTLRDIRAQ HPDAELFFIT GADAVAEIMQ 180
  181 WKDADLMWDL AHFVAVTRPG YSSPDGVTLP EGKVDTLEIP ALAISSTDVR RRAEHDEPVW 240
  241 YLVPDGVVQY IGKHGLYSYE D

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.522879
Match:	1kamA
Description:	Nicotinamide mononucleotide (NMN) adenylyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nicotinate-nucleotide adenylyltransferase activity	2.83520682135534	bayes_pls_golite062009
nicotinamide-nucleotide adenylyltransferase activity	2.57110502211876	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	2.54008423253828	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	2.54008423253828	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	2.52910114154477	bayes_pls_golite062009
catalytic activity	2.37674226834122	bayes_pls_golite062009
ligase activity	1.92894388839884	bayes_pls_golite062009
adenylyltransferase activity	1.08055019963499	bayes_pls_golite062009
pantetheine-phosphate adenylyltransferase activity	0.454904507512502	bayes_pls_golite062009
pantoate-beta-alanine ligase activity	0.282286652169846	bayes_pls_golite062009
nucleotidyltransferase activity	0.2293846471193	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: