YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|254759956
Organism:	Bacillus anthracis str. Australia 94
Length:	435 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|254759956.

Description	E-value	Query Range	Subject Range
MTAD_BACHK - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Bacillus thuringiensis subsp. konkukian GN... MTAD_BACCZ - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Bacillus cereus (strain ZK / E33L) GN=mtaD... MTAD_BACHK - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Bacillus thuringiensis subsp. konkukian (s...	1.0E-74	[1..435]	[1..435]
MTAD_BACCR - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Bacillus cereus (strain ATCC 14579 / DSM 3...	7.0E-74	[1..435]	[1..435]
gi\|89156863, gi\|... - gi\|89205120\|ref\|ZP_01183692.1\| Amidohydrolase:Amidohydrolase-like [Bacillus weihenstephanensis KBAB4...	4.0E-73	[2..435]	[8..441]
gi\|21228381, gi\|... - gi\|21228381\|ref\|NP_634303.1\| N-ethylammeline chlorohydrolase [Methanosarcina mazei Go1], gi\|20906853...	6.0E-71	[2..433]	[28..451]
MTAD_BACCN - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Bacillus cytotoxicus (strain DSM 22905 / C...	3.0E-70	[1..434]	[1..434]
Y1951_BACC1, YJ5... - (O31352) Hypothetical protein BCE1951 (ORF3), Uncharacterized protein BCE_1951 - Bacillus cereus (st...	9.0E-70	[13..435]	[1..423]
gi\|51977022, gi\|... - gi\|52143553\|ref\|YP_083276.1\| chlorohydrolase [Bacillus cereus E33L], gi\|51977022\|gb\|AAU18572.1\| chlo...	1.0E-69	[13..435]	[1..423]
gi\|19915122, gi\|... - gi\|20090140\|ref\|NP_616215.1\| N-ethylammeline chlorohydrolase [Methanosarcina acetivorans C2A], gi\|19...	7.0E-69	[2..433]	[13..436]
gi\|47557580, gi\|... - gi\|47565590\|ref\|ZP_00236631.1\| Atz/Trz family protein [Bacillus cereus G9241], gi\|47557580\|gb\|EAL159...	1.0E-68	[13..435]	[1..423]
MTAD_THEP3 - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Thermoanaerobacter pseudethanolicus (strai... MTAD_THEPX - 5-methylthioadenosine/S-adenosylhomocysteine deaminase OS=Thermoanaerobacter sp. (strain X514) GN=mt... gi\|241883707, gi... - gi\|241903909\|ref\|ZP_04788624.1\| amidohydrolase [Thermoanaerobacter brockii subsp. finnii Ako-1], gi\|... gi\|242230758, gi... - gi\|242257720\|ref\|ZP_04802574.1\| amidohydrolase [Thermoanaerobacter sp. X513], gi\|242230758\|gb\|EES331...	1.0E-68	[1..433]	[1..428]

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Predicted Domain #1

Region A:
Residues: [1-435]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTTYVNATI VTMNEQNEVI ENGYIIVEND KIIDVNSGEF ASDFEVDEVI DMKGKWVLPG  60
   61 LVNTHTHVVM SLLRGIGDDM LLQPWLETRI WPLESQFTPE LAVASTELGL LEMVKSGTTS 120
  121 FSDMFNPIGV DQDAIMETVS RSGMRAAVSR TLFSFGTQED EKKAIEEAEK YVKRYYNESG 180
  181 MLTTMVAPHS PYTCSTELLE ECARIAVENQ TMVHIHLSET EREVRDIEAQ YGKRPVEYVA 240
  241 SCGLFKRPTV IAHGVVLNDN ERAFLAEHDV RVAHNPNSNL KLGSGIANVK AMLEAGMKVG 300
  301 IATDSVASNN NLDMFEEMRI ATLLQKGIHQ DATALPVETA LTLATKGAAE VIGMKQTGSL 360
  361 EVGKCADFIT IDPSNKPHLQ PADEVLSHLV YAASGKDISD VIINGKRVVW NGECKTLDEE 420
  421 RIIFEASRYK RGLQR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.522879
Match:	1p1mA
Description:	Hypothetical protein TM0936; Hypothetical protein TM0936, probable catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
guanine deaminase activity	3.78802420851729	bayes_pls_golite062009
hydrolase activity	3.06979421893431	bayes_pls_golite062009
adenine deaminase activity	1.87830487335945	bayes_pls_golite062009
deaminase activity	1.79186203771221	bayes_pls_golite062009
catalytic activity	1.70199291046899	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1.60895003474033	bayes_pls_golite062009
dihydropyrimidinase activity	1.51712244686012	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	0.787370269329878	bayes_pls_golite062009
nucleic acid binding	0.629962267754185	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	0.573107361273483	bayes_pls_golite062009
binding	0.514083592777841	bayes_pls_golite062009
transcription regulator activity	0.506159010274668	bayes_pls_golite062009
DNA binding	0.462348875991261	bayes_pls_golite062009
peptidase activity	0.370872229900721	bayes_pls_golite062009
dihydroorotase activity	0.203044795244555	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: