YRC Public Data Repository - Protein Structure Prediction

Protein:	TIM10_DEBHA
Organism:	Debaryomyces hansenii CBS767
Length:	91 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIM10_DEBHA.

Description	E-value	Query Range	Subject Range
gi\|50766075 - gi\|50766075\|ref\|XP_422986.1\| PREDICTED: similar to translocase of inner mitochondrial membrane 10 ho...	105.0	[0..2]	[91..116]
gi\|87248623, gi\|... - gi\|87248623\|gb\|ABD36364.1\| mitochondrial intermembrane space translocase subunit Tim10 [Bombyx mori]...	98.0	[0..6]	[91..1]
gi\|114195880, gi... - gi\|115388581\|ref\|XP_001211796.1\| mitochondrial import inner membrane translocase subunit tim10 [Aspe...	98.0	[0..1]	[90..1]
TIM10_YARLI - Mitochondrial import inner membrane translocase subunit TIM10 OS=Yarrowia lipolytica (strain CLIB 12... TIM10_YARLI - Mitochondrial import inner membrane translocase subunit TIM10 OS=Yarrowia lipolytica GN=TIM10 PE=3 S...	97.0	[0..2]	[76..4]
TIM10_ASPFU - Mitochondrial import inner membrane translocase subunit tim10 OS=Aspergillus fumigatus GN=tim10 PE=3... TIM10_ASPFU - Mitochondrial import inner membrane translocase subunit tim10 OS=Neosartorya fumigata (strain ATCC M... gi\|159130673 - gi\|159130673\|gb\|EDP55786.1\| mitochondrial intermembrane space translocase subunit Tim10, putative [A... gi\|119496885, gi... - gi\|119496885\|ref\|XP_001265216.1\| mitochondrial intermembrane space translocase subunit Tim10, putati...	97.0	[0..1]	[88..1]
gi\|73955150 - gi\|73955150\|ref\|XP_854099.1\| PREDICTED: similar to Mitochondrial import inner membrane translocase s...	95.0	[0..1]	[87..166]
TIM10_EMENI, IM1... - Mitochondrial import inner membrane translocase subunit tim10 OS=Emericella nidulans GN=tim10 PE=3 S... TIM10_EMENI - Mitochondrial import inner membrane translocase subunit tim10 OS=Emericella nidulans (strain FGSC A4...	93.0	[0..1]	[78..1]
ORFP:10389 - YHR005C-A, Contig c37 119194-119475 TIM10 - Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 comple... gi\|190405788 - gi\|190405788\|gb\|EDV09055.1\| mitochondrial import inner membrane translocase subunit TIM10 [Saccharom... TIM10_YEAST - Mitochondrial import inner membrane translocase subunit TIM10 OS=Saccharomyces cerevisiae (strain AT...	92.0	[0..2]	[90..4]
TIM10_ASHGO - Mitochondrial import inner membrane translocase subunit TIM10 OS=Ashbya gossypii GN=TIM10 PE=3 SV=1 TIM10_ASHGO - Mitochondrial import inner membrane translocase subunit TIM10 OS=Ashbya gossypii (strain ATCC 10895 ...	91.0	[0..1]	[86..1]
gi\|47218441 - gi\|47218441\|emb\|CAG03713.1\| unnamed protein product [Tetraodon nigroviridis]	91.0	[0..16]	[91..7]

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Predicted Domain #1

Region A:
Residues: [1-91]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGLGGAAPQ ISSQQKLQAA EAELDMVTGM FNQLVEQCHS KCINKTYNDS EVSKQEALCL  60
   61 DRCVAKYFET NVQVGEHMQK MGQSGQFMGR Q

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	18.0
Match:	2bskB
Description:	Crystal structure of the TIM9 Tim10 hexameric complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
P-P-bond-hydrolysis-driven protein transmembrane transporter activity	6.14865333952665	bayes_pls_golite062009
macromolecule transmembrane transporter activity	6.14865333952665	bayes_pls_golite062009
protein transporter activity	3.96569591038426	bayes_pls_golite062009
protein transmembrane transporter activity	3.05578860381335	bayes_pls_golite062009
transporter activity	2.98936530239986	bayes_pls_golite062009
substrate-specific transporter activity	2.87815769573142	bayes_pls_golite062009
binding	2.38169553639759	bayes_pls_golite062009
transmembrane transporter activity	1.67782980643723	bayes_pls_golite062009
protein binding	1.54231655177329	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.42890247609405	bayes_pls_golite062009
primary active transmembrane transporter activity	1.15847548838424	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	1.15316743403707	bayes_pls_golite062009
active transmembrane transporter activity	1.10003802565492	bayes_pls_golite062009
unfolded protein binding	0.0997632819038001	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: