YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|17428178
Organism:	Ralstonia solanacearum
Length:	179 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|17428178.

Description	E-value	Query Range	Subject Range
gi\|50301248 - gi\|50301248\|gb\|AAT73777.1\| TRIM5/cyclophilin A fusion protein [Aotus trivirgatus]	241.0	[0..6]	[178..307]
gi\|37788308 - gi\|37788308\|gb\|AAP44535.1\| cyclophilin-like protein [Triticum aestivum]	222.0	[0..4]	[178..69]
gi\|9955556 - gi\|9955556\|emb\|CAC05440.1\| peptidylprolyl isomerase-like protein [Arabidopsis thaliana]	222.0	[0..2]	[178..79]
gi\|55730219, gi\|... - gi\|75061782\|sp\|Q5R8S7\|PPIA_PONPY Peptidyl-prolyl cis-trans isomerase A (PPIase A) (Rotamase A) (Cycl... gi\|197098846 - gi\|197098846\|ref\|NP_001126060.1\| peptidylprolyl isomerase A [Pongo abelii]	221.0	[0..10]	[179..1]
gi\|82491991 - gi\|82491991\|gb\|ABB77877.1\| peptidylprolyl isomerase A [Gorilla gorilla] PPIA_HYLLA - Peptidyl-prolyl cis-trans isomerase A OS=Hylobates lar GN=PPIA PE=3 SV=3 PPIA_NOMLE - Peptidyl-prolyl cis-trans isomerase A OS=Nomascus leucogenys GN=PPIA PE=3 SV=3 PPIA_SYMSY - Peptidyl-prolyl cis-trans isomerase A OS=Symphalangus syndactylus GN=PPIA PE=3 SV=3 PPIA_GORGO - Peptidyl-prolyl cis-trans isomerase A OS=Gorilla gorilla gorilla GN=PPIA PE=3 SV=3 PPIA_PAPAN - Peptidyl-prolyl cis-trans isomerase A OS=Papio anubis GN=PPIA PE=2 SV=2 gi\|2565299 - gi\|2565299\|gb\|AAB81959.1\| cyclophilin A [Papio hamadryas] gi\|208967012, gi... - gi\|208967012\|dbj\|BAG73520.1\| peptidylprolyl isomerase A [synthetic construct], gi\|123998379\|gb\|ABM86... PPIA_CHLAE - Peptidyl-prolyl cis-trans isomerase A OS=Chlorocebus aethiops GN=PPIA PE=2 SV=2 gi\|90075960 - gi\|90075960\|dbj\|BAE87660.1\| unnamed protein product [Macaca fascicularis] PPIA - peptidylprolyl isomerase A (cyclophilin A) PPIA_MACMU - Peptidyl-prolyl cis-trans isomerase A OS=Macaca mulatta GN=PPIA PE=1 SV=2 gi\|31615579, gi\|... - gi\|31615580\|pdb\|1M9Y\|F Chain F, X-Ray Crystal Structure Of Cyclophilin AHIV-1 Ca N- Terminal Domain ... PPIA_PANPA - Peptidyl-prolyl cis-trans isomerase A OS=Pan paniscus GN=PPIA PE=3 SV=3 PPIA_PANTR - Peptidyl-prolyl cis-trans isomerase A OS=Pan troglodytes GN=PPIA PE=3 SV=3 PPIA_PONPY - Peptidyl-prolyl cis-trans isomerase A OS=Pongo pygmaeus GN=PPIA PE=2 SV=4	221.0	[0..10]	[179..1]

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Predicted Domain #1

Region A:
Residues: [1-179]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLRFSAKEL TMTQVKLHTN HGDITLALDA EKAPKSVANF VHYVKKGHYN GTVFHRVIKG  60
   61 FMIQGGGFEP GADMKQKPTD APIDNEANNG LKNERGSIAM ARTNDPHSAT AQFFINVVDN 120
  121 DFLNHTSPTP QGWGYAVFGK VTEGLDVVDK IRAVRTGNRG YHQDVPMEDV VIESAEVIE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	50.221849
Match:	2nulA
Description:	PEPTIDYLPROLYL ISOMERASE FROM E. COLI
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidyl-prolyl cis-trans isomerase activity	3.73853378771688	bayes_pls_golite062009
cis-trans isomerase activity	3.66963215732405	bayes_pls_golite062009
isomerase activity	1.96529188741504	bayes_pls_golite062009
binding	1.46018233647024	bayes_pls_golite062009
unfolded protein binding	1.38124355054041	bayes_pls_golite062009
RNA binding	1.36609500767021	bayes_pls_golite062009
nucleic acid binding	0.939772862764466	bayes_pls_golite062009
catalytic activity	0.748655649755714	bayes_pls_golite062009
mRNA binding	0.210589563207907	bayes_pls_golite062009
protein binding	0.130251391659493	bayes_pls_golite062009
hydrolase activity	0.126773806019757	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: