YRC Public Data Repository - Protein Structure Prediction

Protein:	ENSMMUT000000328...
Organism:	Macaca mulatta
Length:	140 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ENSMMUT000000328....

Description	E-value	Query Range	Subject Range
gi\|76675933 - gi\|76675933\|ref\|XP_878544.1\| PREDICTED: similar to profilin 2 isoform b isoform 2 [Bos taurus]	9.0E-50	[1..137]	[1..137]
PROF2_RAT - Profilin-2 OS=Rattus norvegicus GN=Pfn2 PE=1 SV=3	1.0E-49	[1..140]	[1..140]
PROF1_RAT - Profilin-1 OS=Rattus norvegicus GN=Pfn1 PE=1 SV=2 PROF1_MOUSE - Profilin-1 OS=Mus musculus GN=Pfn1 PE=1 SV=2	3.0E-49	[1..140]	[1..140]
gi\|119331154, gi... - gi\|53130428\|emb\|CAG31543.1\| hypothetical protein [Gallus gallus], gi\|119331154\|ref\|NP_001073228.1\| p...	1.0E-48	[1..140]	[1..140]
gi\|61372268, gi\|... - gi\|61372268\|gb\|AAX43813.1\| profilin 1 [synthetic construct], gi\|61372266\|gb\|AAX43812.1\| profilin 1 [...	1.0E-48	[1..140]	[1..140]

Back

Predicted Domain #1

Region A:
Residues: [1-140]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGWQSYVDN LMCDGCCQEA AIVGYCDAKY VWAATAGGVF QSITPIEIDM IVGKDREGFF  60
   61 TNGLTLGAKK CSVIRDSLYV DGDCTMDIRT KSQGGEPTYN VAVGRAGRVL VFVMGKEGVH 120
  121 GGGLNKKAYS MAKYLRDSGF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	48.69897
Match:	1d1jA
Description:	Profilin (actin-binding protein)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
actin binding	7.981958446142	bayes_pls_golite062009
cytoskeletal protein binding	6.51470611165788	bayes_pls_golite062009
actin monomer binding	3.80837480536839	bayes_pls_golite062009
binding	3.26636517628678	bayes_pls_golite062009
phosphatidylinositol-4,5-bisphosphate binding	3.08913463974786	bayes_pls_golite062009
protein binding	2.14534188091242	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: