YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|87161726\|ref\|...
Organism:	Staphylococcus aureus subsp. aureus USA300_FPR3757
Length:	207 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|87161726|ref|....

Description	E-value	Query Range	Subject Range
gi\|53688577 - gi\|53688577\|ref\|ZP_00110736.2\| COG2197: Response regulator containing a CheY-like receiver domain an...	213.0	[0..1]	[201..1]
gi\|98660701 - gi\|98660701\|dbj\|GAA02123.1\| unnamed protein product [Pelotomaculum thermopropionicum SI]	213.0	[0..2]	[206..105]
gi\|42780487, gi\|... - gi\|42780487\|ref\|NP_977734.1\| DNA-binding response regulator [Bacillus cereus ATCC 10987], gi\|4273640... gi\|222095033, gi... - gi\|222095033\|ref\|YP_002529093.1\| response regulator [Bacillus cereus Q1], gi\|221239091\|gb\|ACM11801.1... gi\|217068126, gi... - gi\|217958874\|ref\|YP_002337422.1\| DNA-binding response regulator [Bacillus cereus AH187], gi\|21706812... gi\|206977570, gi... - gi\|206977570\|ref\|ZP_03238464.1\| DNA-binding response regulator [Bacillus cereus H3081.97], gi\|206744...	211.0	[0..2]	[206..4]
gi\|163939206, gi... - gi\|89204474\|ref\|ZP_01183051.1\| Response regulator receiver:Transcriptional regulatory protein, C-ter...	211.0	[0..2]	[206..4]
gi\|47556738, gi\|... - gi\|47566185\|ref\|ZP_00237213.1\| two-component response regulator [Bacillus cereus G9241], gi\|47556738...	210.0	[0..2]	[206..4]
gi\|196252895, gi... - gi\|196252895\|ref\|ZP_03151542.1\| two component transcriptional regulator, LuxR family [Clostridium th... gi\|67873312, gi\|... - gi\|67873312\|ref\|ZP_00503591.1\| regulatory protein, LuxR:Response regulator receiver [Clostridium the...	210.0	[0..2]	[204..4]
gi\|225785753, gi... - gi\|225863261\|ref\|YP_002748639.1\| DNA-binding response regulator [Bacillus cereus 03BB102], gi\|225785... gi\|52144036, gi\|... - gi\|52144036\|ref\|YP_082792.1\| response regulator [Bacillus cereus E33L], gi\|51977505\|gb\|AAU19055.1\| r... gi\|118416098, gi... - gi\|118476873\|ref\|YP_894024.1\| response regulator [Bacillus thuringiensis str. Al Hakam], gi\|11841609... gi\|218902506, gi... - gi\|218902506\|ref\|YP_002450340.1\| DNA-binding response regulator [Bacillus cereus AH820], gi\|21853851... gi\|254726203 - gi\|254726203\|ref\|ZP_05187985.1\| DNA-binding response regulator [Bacillus anthracis str. A1055] gi\|196022663, gi... - gi\|196046479\|ref\|ZP_03113704.1\| DNA-binding response regulator [Bacillus cereus 03BB108], gi\|1960226... gi\|196040638, gi... - gi\|196040638\|ref\|ZP_03107937.1\| DNA-binding response regulator [Bacillus cereus NVH0597-99], gi\|1960... gi\|195992031, gi... - gi\|196035354\|ref\|ZP_03102759.1\| DNA-binding response regulator [Bacillus cereus W], gi\|195992031\|gb\|...	210.0	[0..2]	[206..4]
gi\|49477181, gi\|... - gi\|49477181\|ref\|YP_035526.1\| response regulator [Bacillus thuringiensis serovar konkukian str. 97-27...	210.0	[0..2]	[206..4]
gi\|29894995, gi\|... - gi\|30019451\|ref\|NP_831082.1\| two-component response regulator [Bacillus cereus ATCC 14579], gi\|29894... gi\|218164030, gi... - gi\|218236073\|ref\|YP_002366082.1\| DNA-binding response regulator [Bacillus cereus B4264], gi\|21816403...	209.0	[0..2]	[206..4]
gi\|47501725, gi\|... - gi\|47526577\|ref\|YP_017926.1\| DNA-binding response regulator [Bacillus anthracis str. 'Ames Ancestor'... gi\|30255255, gi\|... - gi\|30261401\|ref\|NP_843778.1\| DNA-binding response regulator [Bacillus anthracis str. Ames], gi\|30255... gi\|21399213, gi\|... - gi\|65318666\|ref\|ZP_00391625.1\| COG0745: Response regulators consisting of a CheY-like receiver domai... gi\|227815860, gi... - gi\|227815860\|ref\|YP_002815869.1\| DNA-binding response regulator [Bacillus anthracis str. CDC 684], g... gi\|229604024, gi... - gi\|229604024\|ref\|YP_002865817.1\| DNA-binding response regulator [Bacillus anthracis str. A0248], gi\|... gi\|254682541 - gi\|254682541\|ref\|ZP_05146402.1\| DNA-binding response regulator [Bacillus anthracis str. CNEVA-9066] gi\|167530313, gi... - gi\|167634425\|ref\|ZP_02392746.1\| DNA-binding response regulator [Bacillus anthracis str. A0442], gi\|1... gi\|254733959 - gi\|254733959\|ref\|ZP_05191673.1\| DNA-binding response regulator [Bacillus anthracis str. Western Nort... gi\|254740353 - gi\|254740353\|ref\|ZP_05198044.1\| DNA-binding response regulator [Bacillus anthracis str. Kruger B] gi\|170686885, gi... - gi\|170686885\|ref\|ZP_02878105.1\| DNA-binding response regulator [Bacillus anthracis str. A0465], gi\|1... gi\|254753741 - gi\|254753741\|ref\|ZP_05205776.1\| DNA-binding response regulator [Bacillus anthracis str. Vollum] gi\|49184231, gi\|... - gi\|49184231\|ref\|YP_027483.1\| DNA-binding response regulator [Bacillus anthracis str. Sterne], gi\|491... gi\|167639277, gi... - gi\|167639277\|ref\|ZP_02397549.1\| DNA-binding response regulator [Bacillus anthracis str. A0193], gi\|1... gi\|254758837 - gi\|254758837\|ref\|ZP_05210864.1\| DNA-binding response regulator [Bacillus anthracis str. Australia 94... gi\|172082668, gi... - gi\|177651390\|ref\|ZP_02934179.1\| DNA-binding response regulator [Bacillus anthracis str. A0174], gi\|1... gi\|170706300, gi... - gi\|170706300\|ref\|ZP_02896761.1\| DNA-binding response regulator [Bacillus anthracis str. A0389], gi\|1...	209.0	[0..2]	[206..4]

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Predicted Domain #1

Region A:
Residues: [1-207]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKVILVDDH YIVRQGLRFL LSTIENIEVL QDFADGETFL EYLKEHEHPD IVLLDLVMPG  60
   61 MNGIEITEYI KAHYPDIKVL VLTSYVDDEH VISAINKGAD GYEMKDVEPQ QLIETIRRVM 120
  121 NGEKMIHPKA QDVFETVSQK PHYTNKLSKR EIEVLREMVK GKTNKEIAET LFVSEKTIKT 180
  181 HVSHIFSKLQ VSDRTQAAIY AMENKLI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	37.045757
Match:	1a04A
Description:	Nitrate/nitrite response regulator (NarL); Nitrate/nitrite response regulator (NarL), receiver domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
two-component response regulator activity	7.02872640261738	bayes_pls_golite062009
transcription regulator activity	5.23016166796951	bayes_pls_golite062009
signal transducer activity	4.51666042720644	bayes_pls_golite062009
molecular transducer activity	4.51666042720644	bayes_pls_golite062009
DNA binding	2.75354350283069	bayes_pls_golite062009
nucleic acid binding	2.67056525675208	bayes_pls_golite062009
protein histidine kinase activity	2.35011582062573	bayes_pls_golite062009
two-component sensor activity	2.32303301074957	bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor	2.28838869071567	bayes_pls_golite062009
transcription factor activity	2.12579037300919	bayes_pls_golite062009
binding	1.22427537074115	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: