YRC Public Data Repository - Protein Structure Prediction

Protein:	ADEC_LISMO
Organism:	Listeria monocytogenes EGD-e
Length:	580 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ADEC_LISMO.

Description	E-value	Query Range	Subject Range
gi\|47015953, gi\|... - gi\|47095668\|ref\|ZP_00233275.1\| adenine deaminase [Listeria monocytogenes str. 1/2a F6854], gi\|470159... gi\|254900753, gi... - gi\|254900753\|ref\|ZP_05260677.1\| hypothetical protein LmonJ_13094 [Listeria monocytogenes J0161], gi\|... gi\|133732606, gi... - gi\|254938149\|ref\|ZP_05269846.1\| hypothetical protein LmonF6_13514 [Listeria monocytogenes F6900], gi... gi\|153191213, gi... - gi\|254913762\|ref\|ZP_05263774.1\| hypothetical protein LmonJ2_13234 [Listeria monocytogenes J2818], gi...	511.0	[0..2]	[580..1]
gi\|254880114 - gi\|254880114\|ref\|ZP_05252824.1\| adenine deaminase [Listeria monocytogenes FSL J2-071] gi\|255520517 - gi\|255520517\|ref\|ZP_05387754.1\| adenine deaminase [Listeria monocytogenes FSL J1-175] gi\|254826013 - gi\|254826013\|ref\|ZP_05231014.1\| adenine deaminase [Listeria monocytogenes FSL J1-194] gi\|254853653 - gi\|254853653\|ref\|ZP_05243001.1\| adenine deaminase [Listeria monocytogenes FSL R2-503] gi\|153167515, gi... - gi\|153167515\|ref\|ZP_01927691.1\| adenine deaminase [Listeria monocytogenes FSL N1-017], gi\|133726917\|... ADEC_LISMF - Adenine deaminase OS=Listeria monocytogenes serotype 4b (strain F2365) GN=ade PE=3 SV=1	508.0	[0..2]	[580..1]
ADEC_LISIN - Adenine deaminase OS=Listeria innocua GN=ade PE=3 SV=1 ADEC_LISIN - Adenine deaminase OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=ade PE=3 SV=1	506.0	[0..2]	[580..1]
gi\|47092895, gi\|... - gi\|47092895\|ref\|ZP_00230677.1\| adenine deaminase [Listeria monocytogenes str. 4b H7858], gi\|47018721...	469.0	[0..40]	[580..2]
ADEC_OCEIH - Adenine deaminase OS=Oceanobacillus iheyensis (strain DSM 14371 / JCM 11309 / KCTC 3954 / HTE831) GN... ADEC_OCEIH - Adenine deaminase OS=Oceanobacillus iheyensis GN=ade PE=3 SV=1	466.0	[0..1]	[579..1]
ADEC2_CARHZ - Adenine deaminase 2 OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901) G...	457.0	[0..5]	[577..1]
ADEC_BACHD - Adenine deaminase OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C... ADEC_BACHD - Adenine deaminase OS=Bacillus halodurans GN=ade PE=3 SV=1	450.0	[0..8]	[579..5]
ADEC_BRUME - Adenine deaminase OS=Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094) GN=ade PE=... ADEC_BRUME - Adenine deaminase OS=Brucella melitensis GN=ade PE=3 SV=1	449.0	[0..12]	[575..24]
ADEC_CLOAB - Adenine deaminase OS=Clostridium acetobutylicum GN=ade PE=3 SV=1 ADEC_CLOAB - Adenine deaminase OS=Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / V...	448.0	[0..8]	[575..4]
ADEC_BRUAB - Adenine deaminase OS=Brucella abortus GN=ade PE=3 SV=1 ADEC_BRUAB - Adenine deaminase OS=Brucella abortus biovar 1 (strain 9-941) GN=ade PE=3 SV=1 ADEC_BRUA2 - Adenine deaminase OS=Brucella abortus (strain 2308) GN=ade PE=3 SV=1	448.0	[0..12]	[575..24]

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Predicted Domain #1

Region A:
Residues: [1-414]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVENLKQLQE RVAVSDGRAK ADLVIKNGRI INVFSGEIMD GDIAIKNGYI AGIGSFPDAE  60
   61 KIIDAAGAFI APGFIDAHVH VESAMVTPAE FARVLLPNGV TTIVTDPHEI ANVAGEKGIE 120
  121 FMLEDAKGAP LDMFVMLPSS VPATEGEHNG ETLHAEKLHP LYRHEKVIGL AEVMDFPSVA 180
  181 KGSDDILRKI IDAKKEGGRI DGHGAGLTSA DLNNYLAVGI RTDHESTTAK EATDRLRAGM 240
  241 FVMLREGTVG RDLLQTIPAV SEKNSHRFCF CTDDKLINDL ITEGSINYNI KLAIKNGIDP 300
  301 ITAIQMATIN AANCHNLPYL GAVAAGYQAD IVFLTDIETV EISKVLKNGE VVVDNGVRNE 360
  361 AAFKQQAAVP FVSPPINHHV HLQDLALPLT KETCYVIGMQ PNSLFTEKRI EQVT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.09691
Match:	1a5lC
Description:	alpha-Subunit of urease; alpha-subunit of urease, catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	2.09478447332528	bayes_pls_golite062009
catalytic activity	2.072432847481	bayes_pls_golite062009
hydrolase activity	2.06578679075873	bayes_pls_golite062009
deaminase activity	2.00485136695944	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1.2382202418205	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	0.97576964967771	bayes_pls_golite062009
adenine deaminase activity	0.56372605168514	bayes_pls_golite062009
dihydroorotase activity	0.44266757158292	bayes_pls_golite062009
guanine deaminase activity	0.22133469174284	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [415-580]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IQGGKFVPTV ENDLLKMAVV ERHHDTGCVG VGIVKGFGLT EGAIATTVAH DSHNIVAVGV  60
   61 SDEAMKAAID HITQTGGGIA VVNGAGQVLH DLALPIAGLL SDKSYEEVEN DLAGLLNAFK 120
  121 QISTANGFDP FLTLSFLTLP VIPELKLTDQ GLFDFATFQI ISNEVN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: