YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|20807674, gi\|...
Organism:	Thermoanaerobacter tengcongensis MB4
Length:	133 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|20807674, gi|....

Description	E-value	Query Range	Subject Range
gi\|20808750, gi\|... - gi\|20808750\|ref\|NP_623921.1\| lactoylglutathione lyase and related lyase [Thermoanaerobacter tengcong... gi\|20808750 - gi\|20808750\|ref\|NP_623921.1\| Lactoylglutathione lyase and related lyase [Thermoanaerobacter tengcong...	123.0	[0..1]	[132..1]
gi\|53763628, gi\|... - gi\|75906364\|ref\|YP_320660.1\| glyoxalase I [Anabaena variabilis ATCC 29413], gi\|75700089\|gb\|ABA19765....	123.0	[0..3]	[131..1]
gi\|71669193, gi\|... - gi\|71677562\|ref\|ZP_00675298.1\| Glyoxalase I [Trichodesmium erythraeum IMS101], gi\|71669193\|gb\|EAO258...	122.0	[0..3]	[131..1]
gi\|237503531, gi... - gi\|237810899\|ref\|YP_002895350.1\| lactoylglutathione lyase (Methylglyoxalase)(Aldoketomutase) (Glyoxa... gi\|76809246, gi\|... - gi\|76809246\|ref\|YP_332289.1\| lactoylglutathione lyase [Burkholderia pseudomallei 1710b], gi\|76578699...	121.0	[0..2]	[132..109]
gi\|25529923 - pir\|\|AB2096 lactoylglutathione lyase [imported] - Nostoc sp. (strain PCC 7120) gi\|17229813, gi\|... - gi\|17229813\|ref\|NP_486361.1\| lactoylglutathione lyase [Nostoc sp. PCC 7120], gi\|17131413\|dbj\|BAB7402...	121.0	[0..3]	[131..1]
gi\|98661946 - gi\|98661946\|dbj\|GAA01143.1\| unnamed protein product [Pelotomaculum thermopropionicum SI]	121.0	[0..1]	[133..22]
gi\|186466114, gi... - gi\|23128141\|ref\|ZP_00109995.1\| COG0346: Lactoylglutathione lyase and related lyases [Nostoc punctifo...	120.0	[0..3]	[131..1]
gi\|227081184, gi... - gi\|227081184\|ref\|YP_002809735.1\| lactoylglutathione lyase [Vibrio cholerae M66-2], gi\|227009072\|gb\|A... gi\|153829533, gi... - gi\|153829533\|ref\|ZP_01982200.1\| lactoylglutathione lyase [Vibrio cholerae 623-39], gi\|148874993\|gb\|E... gi\|229350904, gi... - gi\|229510939\|ref\|ZP_04400418.1\| lactoylglutathione lyase [Vibrio cholerae B33], gi\|229350904\|gb\|EEO1... gi\|229515396, gi... - gi\|229515396\|ref\|ZP_04404855.1\| lactoylglutathione lyase [Vibrio cholerae TMA 21], gi\|229347165\|gb\|E... gi\|9655474, gi\|1... - gi\|9655474\|gb\|AAF94171.1\| lactoylglutathione lyase [Vibrio cholerae O1 biovar El Tor str. N16961], g... gi\|227012827, gi... - gi\|227117377\|ref\|YP_002819273.1\| lactoylglutathione lyase [Vibrio cholerae O395], gi\|227012827\|gb\|AC... gi\|229357614, gi... - gi\|229505391\|ref\|ZP_04394901.1\| lactoylglutathione lyase [Vibrio cholerae BX 330286], gi\|229357614\|g... gi\|254843845, gi... - gi\|254848140\|ref\|ZP_05237490.1\| lactoylglutathione lyase [Vibrio cholerae MO10], gi\|254843845\|gb\|EET... gi\|229344775, gi... - gi\|229518060\|ref\|ZP_04407504.1\| lactoylglutathione lyase [Vibrio cholerae RC9], gi\|229344775\|gb\|EEO0... gi\|121628268, gi... - gi\|121729982\|ref\|ZP_01682399.1\| lactoylglutathione lyase [Vibrio cholerae V52], gi\|121628268\|gb\|EAX6... gi\|229371065, gi... - gi\|229608410\|ref\|YP_002879058.1\| lactoylglutathione lyase [Vibrio cholerae MJ-1236], gi\|229371065\|gb... LGUL_VIBCH - (Q9KT93) Probable lactoylglutathione lyase (EC 4.4.1.5) (Methylglyoxalase) (Aldoketomutase) (Glyoxal...	119.0	[0..4]	[132..51]
gi\|167917625 - gi\|167917625\|ref\|ZP_02504716.1\| lactoylglutathione lyase [Burkholderia pseudomallei BCC215] gi\|160698090, gi... - gi\|254177049\|ref\|ZP_04883706.1\| lactoylglutathione lyase [Burkholderia mallei ATCC 10399], gi\|194315... gi\|167901381 - gi\|167901381\|ref\|ZP_02488586.1\| lactoylglutathione lyase [Burkholderia pseudomallei NCTC 13177] gi\|225931264, gi... - gi\|226196733\|ref\|ZP_03792313.1\| lactoylglutathione lyase [Burkholderia pseudomallei Pakistan 9], gi\|... gi\|167909610 - gi\|167909610\|ref\|ZP_02496701.1\| lactoylglutathione lyase [Burkholderia pseudomallei 112] gi\|217420133, gi... - gi\|217420133\|ref\|ZP_03451639.1\| lactoylglutathione lyase [Burkholderia pseudomallei 576], gi\|2173974... gi\|82532706, gi\|... - gi\|82532706\|ref\|ZP_00891916.1\| COG0346: Lactoylglutathione lyase and related lyases [Burkholderia ps... gi\|254181752, gi... - gi\|254181752\|ref\|ZP_04888349.1\| lactoylglutathione lyase [Burkholderia pseudomallei 1655], gi\|194504... gi\|254187681, gi... - gi\|254187681\|ref\|ZP_04894193.1\| lactoylglutathione lyase [Burkholderia pseudomallei Pasteur 52237], ... gi\|167718169 - gi\|167718169\|ref\|ZP_02401405.1\| lactoylglutathione lyase [Burkholderia pseudomallei DM98] gi\|167737200 - gi\|167737200\|ref\|ZP_02409974.1\| lactoylglutathione lyase [Burkholderia pseudomallei 14] gi\|254259782, gi... - gi\|254259782\|ref\|ZP_04950836.1\| lactoylglutathione lyase [Burkholderia pseudomallei 1710a], gi\|25421... gi\|243061642, gi... - gi\|243061642\|gb\|EES43828.1\| lactoylglutathione lyase [Burkholderia mallei PRL-20], gi\|167002703\|ref\|... gi\|167844382 - gi\|167844382\|ref\|ZP_02469890.1\| lactoylglutathione lyase [Burkholderia pseudomallei B7210] gi\|167892896 - gi\|167892896\|ref\|ZP_02480298.1\| lactoylglutathione lyase [Burkholderia pseudomallei 7894] gi\|167814331 - gi\|167814331\|ref\|ZP_02446011.1\| lactoylglutathione lyase [Burkholderia pseudomallei 91] gi\|167822808 - gi\|167822808\|ref\|ZP_02454279.1\| lactoylglutathione lyase [Burkholderia pseudomallei 9] gi\|126438972, gi... - gi\|126438972\|ref\|YP_001057749.1\| lactoylglutathione lyase [Burkholderia pseudomallei 668], gi\|126218... gi\|124385149, gi... - gi\|124385149\|ref\|YP_001028308.1\| lactoylglutathione lyase [Burkholderia mallei NCTC 10229], gi\|12429... gi\|52208720, gi\|... - gi\|53718306\|ref\|YP_107292.1\| lactoylglutathione lyase [Burkholderia pseudomallei K96243], gi\|5220872... gi\|52428442, gi\|... - gi\|53725019\|ref\|YP_102047.1\| lactoylglutathione lyase [Burkholderia mallei ATCC 23344], gi\|52428442\|... gi\|254360239, gi... - gi\|254360239\|ref\|ZP_04976509.1\| lactoylglutathione lyase [Burkholderia mallei 2002721280], gi\|194573... gi\|134279618, gi... - gi\|134279618\|ref\|ZP_01766330.1\| lactoylglutathione lyase [Burkholderia pseudomallei 305], gi\|1342488... gi\|242317868, gi... - gi\|242317868\|ref\|ZP_04816884.1\| lactoylglutathione lyase [Burkholderia pseudomallei 1106b], gi\|24214... gi\|83676948, gi\|... - gi\|83676948\|ref\|ZP_00938713.1\| COG0346: Lactoylglutathione lyase and related lyases [Burkholderia ps... gi\|83625910, gi\|... - gi\|83625910\|ref\|ZP_00936138.1\| COG0346: Lactoylglutathione lyase and related lyases [Burkholderia ma... gi\|67641456, gi\|... - gi\|67641456\|ref\|ZP_00440234.1\| lactoylglutathione lyase [Burkholderia mallei GB8 horse 4], gi\|238522... gi\|83620971 - gi\|83620971\|ref\|ZP_00931385.1\| COG0346: Lactoylglutathione lyase and related lyases [Burkholderia ma... gi\|84521850, gi\|... - gi\|84521850\|ref\|ZP_01008986.1\| COG0346: Lactoylglutathione lyase and related lyases [Burkholderia ma... gi\|67647704, gi\|... - gi\|67647704\|ref\|ZP_00445943.1\| COG0346: Lactoylglutathione lyase and related lyases [Burkholderia ma... gi\|85066589 - gi\|85066589\|ref\|ZP_01027442.1\| COG0346: Lactoylglutathione lyase and related lyases [Burkholderia ma...	117.0	[0..3]	[132..1]
gi\|15602852, gi\|... - gi\|15602852\|ref\|NP_245924.1\| hypothetical protein PM0987 [Pasteurella multocida subsp. multocida str... tr\|J6CVB7\|J6CVB7... - Lactoylglutathione lyase OS=Pasteurella multocida subsp. multocida str. Anand1_cattle GN=AAUPMC_1045...	117.0	[0..3]	[132..1]

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Predicted Domain #1

Region A:
Residues: [1-133]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKKVDHIGI AVKSIEEARK FYEEVLGLKV TGIEEVKEQK VKTAFIPVGD SEIELLESTS  60
   61 EDGPVAKFIE KRGEGIHHIA LQVDDIEKAL EELKGKGVKL IDEVPRYGAG GAKIAFVHPK 120
  121 NANGVLLELC ERD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.0
Match:	1f9zA
Description:	Glyoxalase I (lactoylglutathione lyase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.58822083914233	bayes_pls_golite062009
methylmalonyl-CoA epimerase activity	0.634998966787841	bayes_pls_golite062009
lyase activity	0.06622411219947	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: