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View Structure Prediction Details

Protein: NUP57_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 541 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NUP57_YEAST.

Description E-value Query
Range		 Subject
Range
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 2.0E-83 [139..536] [34..423]
nup44 - nucleoporin Nup44
NUP44_SCHPO - Nucleoporin nup44 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=nup44 PE=2 SV=1
 4.0E-81 [139..536] [3..392]
NUP57 - Nucleoporin, essential subunit of the nuclear pore complex (NPC), functions as the organizing center...
NUP57_YEAST - Nucleoporin NUP57 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NUP57 PE=1 SV=1
 3.0E-77 [1..541] [1..541]
gi|19309407 - gi|19309407|emb|CAD27306.1| putative nucleoporin [Aspergillus fumigatus]
gi|70995682, gi|... - gi|70995682|ref|XP_752596.1| nucleoporin, putative [Aspergillus fumigatus Af293], gi|66850231|gb|EAL...
 4.0E-71 [94..520] [4..414]
NUP54_RAT - Nuclear pore complex protein Nup54 OS=Rattus norvegicus GN=Nup54 PE=1 SV=1
 2.0E-59 [325..535] [302..492]
NUP54_ARATH - Nuclear pore complex protein NUP54 OS=Arabidopsis thaliana GN=NUP54 PE=1 SV=1
 6.0E-57 [151..534] [1..363]
gi|18032249 - gi|18032249|gb|AAL56659.1|AF231130_1 NUP196 nucleoporin [Homo sapiens]
 4.0E-45 [2..328] [42..408]
gi|6010435 - gi|6010435|gb|AAF01135.1| erythrocyte membrane protein 3 [Plasmodium falciparum]
 2.0E-42 [5..333] [1352..1680]

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Predicted Domain #1
Region A:
Residues: [1-287] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFGFSGSNNG FGNKPAGSTG FSFGQNNNNT NTQPSASGFG FGGSQPNSGT ATTGGFGANQ  60
   61 ATNTFGSNQQ SSTGGGLFGN KPALGSLGSS STTASGTTAT GTGLFGQQTA QPQQSTIGGG 120
  121 LFGNKPTTTT GGLFGNSAQN NSTTSGGLFG NKVGSTGSLM GGNSTQNTSN MNAGGLFGAK 180
  181 PQNTTATTGG LFGSKPQGST TNGGLFGSGT QNNNTLGGGG LFGQSQQPQT NTAPGLGNTV 240
  241 STQPSFAWSK PSTGSNLQQQ QQQQIQVPLQ QTQAIAQQQQ LSNYPQQ

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 14.2
Match: 1ldvA
Description: No description for 1ldvA was found.

Predicted Domain #2
Region A:
Residues: [288-427] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IQEQVLKCKE SWDPNTTKTK LRAFVYNKVN ETEAILYTKP GHVLQEEWDQ AMEKKPSPQT  60
   61 IPIQIYGFEG LNQRNQVQTE NVAQARIILN HILEKSTQLQ QKHELDTASR ILKAQSRNVE 120
  121 IEKRILKLGT QLATLKNRGL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.221849
Match: 1avc__
Description: Annexin VI
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [428-541] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLGIAEEKMW SQFQTLLQRS EDPAGLGKTN ELWARLAILK ERAKNISSQL DSKLMVFNDD  60
   61 TKNQDSMSKG TGEESNDRIN KIVEILTNQQ RGITYLNEVL EKDAAIVKKY KNKT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score		 GO
Score		 GO
Term		 SCOP
Match		 SCOP Description
View Download 0.917 0.291 snRNA export from nucleus a.25.1 Ferritin-like

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