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View Structure Prediction Details

Protein: TRM11_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 433 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TRM11_YEAST.

Description E-value Query
Range
Subject
Range
TRM11_MOUSE - tRNA (guanine(10)-N2)-methyltransferase homolog OS=Mus musculus GN=Trmt11 PE=1 SV=1
5.0E-79 [1..430] [7..445]
gi|151945511 - gi|151945511|gb|EDN63752.1| N2-monomethylguanosine-specific tRNA methyltransferase [Saccharomyces ce...
gi|207341461 - gi|207341461|gb|EDZ69512.1| YOL124Cp-like protein [Saccharomyces cerevisiae AWRI1631]
TRM11_YEAST - tRNA (guanine(10)-N2)-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=...
TRM11 - Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required f...
7.0E-76 [1..433] [1..433]
gi|9294300, gi|1... - gi|9294300|dbj|BAB02202.1| unnamed protein product [Arabidopsis thaliana], gi|18404931|ref|NP_566792...
7.0E-61 [2..429] [1..437]
CE29909 - status:Partially_confirmed UniProt:Q9N4H1 protein_id:AAF36002.2
3.0E-57 [1..430] [1..427]
trm11 - tRNA (guanosine) methyltransferase Trm11
gi|19113289 - gi|19113289|ref|NP_596497.1| hypothetical protein SPBC16D10.02 [Schizosaccharomyces pombe 972h-]
8.0E-54 [1..428] [1..451]
gi|7767522 - gi|7767522|gb|AAF69138.1|AF228680_2 HsdM [Lactococcus lactis]
gi|9789463, gi|3... - gi|9789463|gb|AAF98315.1|AF243383_16 HsdM [Lactococcus lactis subsp. lactis], gi|32455489|ref|NP_862...
8.0E-45 [1..416] [1..417]
gi|57208456, gi|... - gi|57208456|emb|CAI42396.1| chromosome 6 open reading frame 75 [Homo sapiens], gi|119568511|gb|EAW48...
2.0E-43 [1..245] [7..251]
gi|11279435, gi|... - gi|6137148|gb|AAF04357.1| type IC modification subunit [Streptococcus thermophilus], pir||T44803 typ...
1.0E-42 [18..416] [7..411]

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Predicted Domain #1
Region A:
Residues: [1-112]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKYLLYMVQ VHLNFRRAEL ESLADLYNLS IDFSQYDANS PFFIVELEND QQAKDWIKRS  60
   61 ILTRGIYEYW GQGTTLDELH KDIQRQSNFE QDLQLKFKHS TFKFEFECYK GN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.678 d.93.1 SH2 domain
View Download 0.610 d.58.4 Dimeric alpha+beta barrel
View Download 0.504 b.23.1 Spermadhesin, CUB domain
View Download 0.615 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.566 d.15.6 Superantigen toxins, C-terminal domain
View Download 0.447 d.16.1 FAD-linked reductases, C-terminal domain
View Download 0.439 a.4.1 Homeodomain-like
View Download 0.410 d.110.4 SNARE-like
View Download 0.409 a.7.7 BAG domain
View Download 0.407 d.79.2 Tubulin/Dihydroxyacetone kinase C-terminal domain
View Download 0.390 a.81.1 N-terminal domain of DnaB helicase
View Download 0.388 d.185.1 LuxS/MPP-like metallohydrolase
View Download 0.388 d.150.1 4'-phosphopantetheinyl transferase
View Download 0.380 d.146.1 Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain
View Download 0.365 d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.357 d.52.7 Ribosome-binding factor A, RbfA
View Download 0.353 a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.337 d.74.1 Pterin-4a-carbinolamine dehydratase (PCD)/dimerization cofactor of HNF1 (DCoH)
View Download 0.331 d.96.1 Tetrahydrobiopterin biosynthesis enzymes-like
View Download 0.330 a.118.1 ARM repeat
View Download 0.328 a.39.1 EF-hand
View Download 0.321 d.38.1 Thioesterase/thiol ester dehydrase-isomerase
View Download 0.308 d.96.1 Tetrahydrobiopterin biosynthesis enzymes-like
View Download 0.307 d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.300 d.38.1 Thioesterase/thiol ester dehydrase-isomerase
View Download 0.298 d.58.35 Pseudouridine synthase
View Download 0.296 a.71.2 Helical domain of Sec23/24
View Download 0.288 f.32.1 a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.285 a.6.1 Putative DNA-binding domain
View Download 0.281 a.26.1 4-helical cytokines
View Download 0.275 a.47.2 t-snare proteins
View Download 0.274 d.129.2 Phosphoglucomutase, C-terminal domain
View Download 0.271 a.24.3 Cytochromes
View Download 0.242 d.58.47 Hypothetical protein VC0424
View Download 0.236 a.7.6 Ribosomal protein S20
View Download 0.234 d.208.1 MTH1598-like
View Download 0.226 b.2.4 Alpha-macroglobulin receptor domain
View Download 0.224 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.219 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.217 a.26.1 4-helical cytokines
View Download 0.213 a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.212 b.1.18 E set domains
View Download 0.209 d.58.17 Metal-binding domain
View Download 0.204 a.64.1 Saposin

Predicted Domain #2
Region A:
Residues: [113-191]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKAKRVEQIE TFRYLGFEGK IDMKHPQEVF TVIEEYTPIS ENVGGKTPTR IYFGRQVQMS  60
   61 NRSAMEKYDL KKRPYKGTT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.69897
Match: 1g60A_
Description: Methyltransferase mboII
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [192-433]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFEAELSLVS ANIAQVKPGT IMYDPFAGTG SFLVAGGHFG SLVIGSDIDG RMIRGKGAQV  60
   61 NISANFKKYG ESSQFLDVLT MDFTNNALRN NLVIDTILCD PPYGIRESIK VLGAKDPERF 120
  121 LGKEDMEIDG EKAYLRRDYI PTKKPYALDS LLDDLLQYSS ERLPIGGRLA FWMPTANDAN 180
  181 IETIVPMHEN LELKYNCVQE FNKWSRRLLV YINRGSTFNG SSNHGIKRSK DNFRERYFNN 240
  241 FN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.0
Match: 2admA_
Description: DNA methylase TaqI
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle