YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24372411, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	472 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24372411, gi|....

Description	E-value	Query Range	Subject Range
gi\|71488678, gi\|... - gi\|71545481\|ref\|ZP_00666412.1\| RND efflux system, outer membrane lipoprotein, NodT [Syntrophobacter ...	314.0	[0..9]	[465..206]
gi\|157412124 - gi\|157412124\|ref\|YP_001481465.1\| copper/silver efflux system outer membrane protein CusC [Escherichi... gi\|218697184, gi... - gi\|218697184\|ref\|YP_002404851.1\| copper/silver efflux system outer membrane protein CusC [Escherichi... gi\|99867149 - gi\|99867149\|gb\|ABF67794.1\| SilC [Escherichia coli APEC O1]	299.0	[0..4]	[464..94]
gi\|67981567, gi\|... - gi\|95930203\|ref\|ZP_01312941.1\| Hydrophobe/amphiphile efflux-1 HAE1 [Desulfuromonas acetoxidans DSM 6...	299.0	[0..9]	[466..1036]
gi\|77810523, gi\|... - gi\|77814476\|ref\|ZP_00813735.1\| RND efflux system, outer membrane lipoprotein, NodT [Shewanella putre...	296.0	[0..4]	[464..94]
gi\|78684782, gi\|... - gi\|78684782\|ref\|ZP_00849564.1\| RND efflux system, outer membrane lipoprotein, NodT [Shewanella sp. A...	295.0	[0..4]	[464..94]
gi\|46446186, gi\|... - gi\|46446186\|ref\|YP_007551.1\| putative outer membrane protein, componenet of multidrug efflux systems...	295.0	[0..21]	[468..1]
gi\|85858611, gi\|... - gi\|85858611\|ref\|YP_460813.1\| type I secretion outer membrane protein [Syntrophus aciditrophicus SB],...	294.0	[0..16]	[464..40]
gi\|94731686, gi\|... - gi\|94987437\|ref\|YP_595370.1\| outer membrane efflux protein [Lawsonia intracellularis PHE/MN1-00], gi...	293.0	[0..16]	[465..3]
gi\|23471294, gi\|... - gi\|66047236\|ref\|YP_237077.1\| RND efflux system, outer membrane lipoprotein, NodT [Pseudomonas syring...	291.0	[0..15]	[464..1]
gi\|71741812, gi\|... - gi\|71837530\|ref\|ZP_00677294.1\| RND efflux system, outer membrane lipoprotein, NodT [Pelobacter propi...	291.0	[0..13]	[465..4]

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Predicted Domain #1

Region A:
Residues: [1-472]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNKVLMHQN KLRTLKLSVI AISIALLSGC GALMRSDFEP PALQVPEQWQ HTAVNSQVSL  60
   61 DPWWQKFNQP ELNQLISQVL SSNNDLTIAT LTLQKARLQA GLARDELYPQ LSSNNAASVN 120
  121 KPLEGGSSSK AYKANLSVSY EVDLWGKVSA NIDQAQWTAL ASVEDRESTA HSLVATTASL 180
  181 YWQIGYLHQR IELSNKSIEY SRQTLALTER QYASGAVTEL NVLESLRSLA GQEAAHSQLL 240
  241 QQLVEAENAL AILLNRAPGQ VAVEIKQLPD SAVPEIGVGI PADLIGRRPD VKAALYQLRS 300
  301 ALASKNATYA SYFPSLSLTG SVGESTSELK ELLRNPVGSL GAGLMLPFLQ WNQMQINNDL 360
  361 ADIDYQTAIV NYRKTLYSAF EDVDNAISAK QQYAYQGEKL EQQFSAAAQA EAIYESQYRH 420
  421 GAIGIQNWID AQENRRSAEA ALLENRYNQL TAQATLYQAL GGSDIAPLLA DN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	68.69897
Match:	1wp1A
Description:	Crystal structure of the drug-discharge outer membrane protein, OprM
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
drug transmembrane transporter activity	4.81710579303325	bayes_pls_golite062009
	4.35844117790122	bayes_pls_golite062009
	4.29225678658868	bayes_pls_golite062009
transporter activity	4.2806100513341	bayes_pls_golite062009
transmembrane transporter activity	2.91628575119399	bayes_pls_golite062009
porin activity	0.960340223825989	bayes_pls_golite062009
binding	0.666039242029224	bayes_pls_golite062009
channel activity	0.517545908208242	bayes_pls_golite062009
passive transmembrane transporter activity	0.517545908208242	bayes_pls_golite062009
efflux transmembrane transporter activity	0.381147202210091	bayes_pls_golite062009
protein binding	0.0827883348198969	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: