YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24347002, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	229 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24347002, gi|....

Description	E-value	Query Range	Subject Range
gi\|69111664 - gi\|69111664\|gb\|AAZ03394.1\| Aqp4-Luc fusion protein [Reporter vector pmuAqp4-Luc]	214.0	[0..2]	[228..13]
gi\|69111702 - gi\|69111702\|gb\|AAZ03395.1\| Aqp4-Luc fusion protein [Reporter vector praAqp4-Luc]	212.0	[0..2]	[228..13]
gi\|115459788, gi... - gi\|50927737\|ref\|XP_473424.1\| OSJNBb0034G17.15 [Oryza sativa (japonica cultivar-group)], gi\|38605857\|...	208.0	[0..2]	[228..18]
gi\|94399989 - gi\|94399989\|ref\|XP_001003734.1\| PREDICTED: similar to aquaporin 5 [Mus musculus]	200.0	[0..2]	[228..165]
gi\|73961781 - gi\|73961781\|ref\|XP_855456.1\| PREDICTED: similar to Aquaporin 4 (WCH4) (Mercurial-insensitive water c...	198.0	[0..2]	[228..110]
gi\|151944919 - gi\|151944919\|gb\|EDN63174.1\| conserved protein [Saccharomyces cerevisiae YJM789] YFL054C - Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the prese... YFF4_YEAST - Uncharacterized membrane protein YFL054C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...	197.0	[0..2]	[204..347]
gi\|38198152, gi\|... - gi\|38198152\|emb\|CAE53882.1\| aquaporin [Ricinus communis], gi\|255571849\|ref\|XP_002526867.1\| Aquaporin...	197.0	[0..2]	[228..53]
gi\|2373401 - gi\|2373401\|dbj\|BAA22097.1\| transmembrane protein [Arabidopsis thaliana]	196.0	[0..2]	[228..52]
gi\|89212808 - gi\|89212808\|gb\|ABD63904.1\| aquaporin 1 [Gossypium hirsutum]	196.0	[0..2]	[228..51]
gi\|114612688 - gi\|114612688\|ref\|XP_001166359.1\| PREDICTED: aquaporin 1 isoform 2 [Pan troglodytes]	196.0	[0..2]	[229..11]

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Predicted Domain #1

Region A:
Residues: [1-229]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQKMAAEFL GTLWLVLGGC GSAVLAAAFP EVGIGLLGVS LAFGLTVLTM AFAIGHISGC  60
   61 HLNPAVSFGL WAGGRFPTSE LLPYIIAQVA GGIAGAGVLY LIASGQEGFS LAAGFASNGF 120
  121 GEHSPGGYSM ISVMICEIVM TLFFLLVILG STDERAPKGF APIAIGLCLT LIHLISIPIS 180
  181 NTSVNPARST GPALFVGDWA VSQLWLFWAA PIIGAILAGV IYRYFNAAK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.09691
Match:	1rc2B
Description:	2.5 Angstrom Resolution X-ray Structure of Aquaporin Z
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
water transmembrane transporter activity	10.3414560257964	bayes_pls_golite062009
water channel activity	10.2169080705067	bayes_pls_golite062009
substrate-specific channel activity	6.49777654791183	bayes_pls_golite062009
passive transmembrane transporter activity	6.47484344601535	bayes_pls_golite062009
channel activity	6.47484344601535	bayes_pls_golite062009
transporter activity	5.23077472964938	bayes_pls_golite062009
substrate-specific transporter activity	5.06520190871345	bayes_pls_golite062009
transmembrane transporter activity	4.83314424546299	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	4.7450921192571	bayes_pls_golite062009
glycerol channel activity	4.65460547189577	bayes_pls_golite062009
ion transmembrane transporter activity	2.89377210429696	bayes_pls_golite062009
cation transmembrane transporter activity	2.66719193997824	bayes_pls_golite062009
pyrimidine transmembrane transporter activity	2.42183378687544	bayes_pls_golite062009
metal ion transmembrane transporter activity	2.14052261196782	bayes_pls_golite062009
amide transmembrane transporter activity	1.91157799400296	bayes_pls_golite062009
urea transmembrane transporter activity	1.91157799400296	bayes_pls_golite062009
urea channel activity	1.91157799400296	bayes_pls_golite062009
organic acid transmembrane transporter activity	1.57078059027065	bayes_pls_golite062009
carboxylic acid transmembrane transporter activity	1.57017437613762	bayes_pls_golite062009
cation channel activity	1.51074107596522	bayes_pls_golite062009
ion channel activity	1.40084800732756	bayes_pls_golite062009
amine transmembrane transporter activity	1.10865678129643	bayes_pls_golite062009
binding	1.09154723976574	bayes_pls_golite062009
nucleobase transmembrane transporter activity	0.911381096418279	bayes_pls_golite062009
purine transmembrane transporter activity	0.911381096418279	bayes_pls_golite062009
alcohol transmembrane transporter activity	0.820388351311438	bayes_pls_golite062009
polyol transmembrane transporter activity	0.820388351311438	bayes_pls_golite062009
glycerol transmembrane transporter activity	0.545299611300918	bayes_pls_golite062009
active transmembrane transporter activity	0.315342449421593	bayes_pls_golite062009
protein binding	0.179478120921785	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: