YRC Public Data Repository - Protein Structure Prediction

Protein:	MUTH_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	223 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MUTH_SHEON.

Description	E-value	Query Range	Subject Range
MUTH_PHOLL - DNA mismatch repair protein MutH OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CI... MUTH_PHOLL - DNA mismatch repair protein mutH OS=Photorhabdus luminescens subsp. laumondii GN=mutH PE=3 SV=1	416.0	[0..6]	[222..10]
MUTH_SALCH - DNA mismatch repair protein MutH OS=Salmonella choleraesuis (strain SC-B67) GN=mutH PE=3 SV=1 MUTH_SALCH - DNA mismatch repair protein mutH OS=Salmonella choleraesuis GN=mutH PE=3 SV=1 MUTH_SALCH - DNA mismatch repair protein mutH OS=Salmonella choleraesuis GN=mutH PE=3 SV=1 MUTH_SALPC - DNA mismatch repair protein MutH OS=Salmonella paratyphi C (strain RKS4594) GN=mutH PE=3 SV=1	413.0	[0..3]	[222..7]
MUTH_SALPB - DNA mismatch repair protein MutH OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=mutH PE=... MUTH_SALNS - DNA mismatch repair protein MutH OS=Salmonella newport (strain SL254) GN=mutH PE=3 SV=1 MUTH_SALHS - DNA mismatch repair protein MutH OS=Salmonella heidelberg (strain SL476) GN=mutH PE=3 SV=1 gi\|194459019, gi... - gi\|194472655\|ref\|ZP_03078639.1\| DNA mismatch repair endonuclease MutH [Salmonella enterica subsp. en... MUTH_SALSV - DNA mismatch repair protein MutH OS=Salmonella schwarzengrund (strain CVM19633) GN=mutH PE=3 SV=1 gi\|168236060, gi... - gi\|197290737\|gb\|EDY30091.1\| DNA mismatch repair endonuclease MutH [Salmonella enterica subsp. enteri... gi\|205338005, gi... - gi\|205338005\|gb\|EDZ24769.1\| DNA mismatch repair endonuclease MutH [Salmonella enterica subsp. enteri... gi\|168463835, gi... - gi\|195633424\|gb\|EDX51838.1\| DNA mismatch repair endonuclease MutH [Salmonella enterica subsp. enteri... gi\|168820265, gi... - gi\|205342879\|gb\|EDZ29643.1\| DNA mismatch repair endonuclease MutH [Salmonella enterica subsp. enteri... gi\|205324783, gi... - gi\|205324783\|gb\|EDZ12622.1\| DNA mismatch repair endonuclease MutH [Salmonella enterica subsp. enteri... lcl\|NC_016856.1_... - [gene=mutH] [protein=DNA mismatch repair protein] [protein_id=YP_005239132.1] [location=3183190..318... MUTH_SALTY - DNA mismatch repair protein MutH OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=... gi\|167993506, gi... - gi\|205328491\|gb\|EDZ15255.1\| DNA mismatch repair endonuclease MutH [Salmonella enterica subsp. enteri... gi\|205334442, gi... - gi\|205334442\|gb\|EDZ21206.1\| DNA mismatch repair endonuclease MutH [Salmonella enterica subsp. enteri... gi\|204928080, gi... - gi\|204928080\|ref\|ZP_03219280.1\| DNA mismatch repair endonuclease MutH [Salmonella enterica subsp. en... MUTH_SALG2 - DNA mismatch repair protein MutH OS=Salmonella gallinarum (strain 287/91 / NCTC 13346) GN=mutH PE=3 ... MUTH_SALEP - DNA mismatch repair protein MutH OS=Salmonella enteritidis PT4 (strain P125109) GN=mutH PE=3 SV=1 MUTH_SALTY - DNA mismatch repair protein mutH OS=Salmonella typhimurium GN=mutH PE=3 SV=1 MUTH_SALA4 - DNA mismatch repair protein MutH OS=Salmonella agona (strain SL483) GN=mutH PE=3 SV=1 gi\|197265268, gi... - gi\|197265268\|ref\|ZP_03165342.1\| DNA mismatch repair endonuclease MutH [Salmonella enterica subsp. en... MUTH_SALDC - DNA mismatch repair protein MutH OS=Salmonella dublin (strain CT_02021853) GN=mutH PE=3 SV=1 gi\|200388888, gi... - gi\|200388888\|ref\|ZP_03215500.1\| DNA mismatch repair endonuclease MutH [Salmonella enterica subsp. en... gi\|238909783 - gi\|238909783\|ref\|ZP_04653620.1\| DNA mismatch repair protein [Salmonella enterica subsp. enterica ser... MUTH_SALPB - DNA mismatch repair protein mutH OS=Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7) GN=mutH PE=... MUTH_SALTY - DNA mismatch repair protein mutH OS=Salmonella typhimurium GN=mutH PE=3 SV=1	412.0	[0..3]	[222..7]
gi\|214000417 - gi\|214000417\|ref\|ZP_03411152.1\| DNA mismatch repair protein [Salmonella enterica subsp. enterica ser... gi\|213976725 - gi\|213976725\|ref\|ZP_03403984.1\| DNA mismatch repair protein [Salmonella enterica subsp. enterica ser... gi\|213861494 - gi\|213861494\|ref\|ZP_03385964.1\| DNA mismatch repair protein [Salmonella enterica subsp. enterica ser... gi\|16761782 - gi\|16761782\|ref\|NP_457399.1\| DNA mismatch repair protein [Salmonella enterica subsp. enterica serova... MUTH_SALTI - DNA mismatch repair protein mutH OS=Salmonella typhi GN=mutH PE=3 SV=1 MUTH_SALTI - DNA mismatch repair protein MutH OS=Salmonella typhi GN=mutH PE=3 SV=1 gi\|29138900, gi\|... - gi\|29143266\|ref\|NP_806608.1\| DNA mismatch repair protein [Salmonella enterica subsp. enterica serova... gi\|213650272 - gi\|213650272\|ref\|ZP_03380325.1\| DNA mismatch repair protein [Salmonella enterica subsp. enterica ser... gi\|213586822 - gi\|213586822\|ref\|ZP_03368648.1\| DNA mismatch repair protein [Salmonella enterica subsp. enterica ser... gi\|213423921 - gi\|213423921\|ref\|ZP_03356901.1\| DNA mismatch repair protein [Salmonella enterica subsp. enterica ser... gi\|213023729 - gi\|213023729\|ref\|ZP_03338176.1\| DNA mismatch repair protein [Salmonella enterica subsp. enterica ser...	412.0	[0..3]	[222..7]
gi\|37678858, gi\|... - gi\|37678858\|ref\|NP_933467.1\| DNA mismatch repair protein [Vibrio vulnificus YJ016], gi\|37197599\|dbj\|...	410.0	[0..7]	[222..27]
MUTH_VIBVU - DNA mismatch repair protein mutH OS=Vibrio vulnificus GN=mutH PE=3 SV=1 MUTH_VIBVY - DNA mismatch repair protein MutH OS=Vibrio vulnificus (strain YJ016) GN=mutH PE=3 SV=2 MUTH_VIBVU - DNA mismatch repair protein MutH OS=Vibrio vulnificus (strain CMCP6) GN=mutH PE=3 SV=1	408.0	[0..7]	[222..5]
MUTH_HISS2 - DNA mismatch repair protein MutH OS=Histophilus somni (strain 2336) GN=mutH PE=3 SV=1	408.0	[0..1]	[219..1]
MUTH_YERPS - DNA mismatch repair protein MutH OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=mutH ... MUTH_YERPS - DNA mismatch repair protein mutH OS=Yersinia pseudotuberculosis GN=mutH PE=3 SV=1 MUTH_YERPB - DNA mismatch repair protein MutH OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=mutH P...	408.0	[0..6]	[222..10]
MUTH_SALPK - DNA mismatch repair protein MutH OS=Salmonella paratyphi A (strain AKU_12601) GN=mutH PE=3 SV=1 MUTH_SALPA - DNA mismatch repair protein mutH OS=Salmonella paratyphi A GN=mutH PE=3 SV=1 MUTH_SALPA - DNA mismatch repair protein MutH OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=mutH PE=3 ...	408.0	[0..5]	[222..9]
MUTH_HAES1 - DNA mismatch repair protein MutH OS=Haemophilus somnus (strain 129Pt) GN=mutH PE=3 SV=1	407.0	[0..1]	[219..1]

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Predicted Domain #1

Region A:
Residues: [1-223]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSIIPPQNL SELLKRANMM AGISLAQIAT HRGINVPNNL KRDKGWVGQL IEMELGATAG  60
   61 SKPEQDFLHL GVELKTIPID NHGKPLETTY VCVAPLTNIE GLTWQNSLVC HKLQRVLWVP 120
  121 VEGERHIPVG ERRIGTPTLW EPDPQEQALL QQDWEEIMEL IALGKVEKLT ARHGEVLQLR 180
  181 PKAANSKAMT HSISEDGSLK MTNPRGFYLK TAFTAMILNK VFG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	114.0
Match:	2azoA
Description:	DNA mismatch repair protein MutH from
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
double-stranded DNA binding	4.65596322324967	bayes_pls_golite062009
endodeoxyribonuclease activity	3.88121538069074	bayes_pls_golite062009
single-stranded DNA specific endodeoxyribonuclease activity	3.87045877570028	bayes_pls_golite062009
deoxyribonuclease activity	3.62965779224499	bayes_pls_golite062009
single-stranded DNA binding	2.01277239394854	bayes_pls_golite062009
structure-specific DNA binding	1.99560174672253	bayes_pls_golite062009
nuclease activity	1.92659045080864	bayes_pls_golite062009
endonuclease activity	1.6546965422816	bayes_pls_golite062009
damaged DNA binding	1.50475020123562	bayes_pls_golite062009
hydrolase activity	1.18004254197954	bayes_pls_golite062009
binding	0.940513659936693	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.878597940882332	bayes_pls_golite062009
catalytic activity	0.816447099398022	bayes_pls_golite062009
nucleic acid binding	0.796780585758145	bayes_pls_golite062009
DNA binding	0.779318309058729	bayes_pls_golite062009
protein binding	0.458550636208588	bayes_pls_golite062009
DNA strand annealing activity	0.103710151681167	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: