YRC Public Data Repository - Protein Structure Prediction

Protein:	HIS8_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	391 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HIS8_SHEON.

Description	E-value	Query Range	Subject Range
AAT_AQUAE - Aspartate aminotransferase OS=Aquifex aeolicus (strain VF5) GN=aspC PE=3 SV=1 AAT_AQUAE - Aspartate aminotransferase OS=Aquifex aeolicus GN=aspC PE=3 SV=1	285.0	[0..32]	[391..1]
AAT1_BACSU - Aspartate aminotransferase OS=Bacillus subtilis GN=aspB PE=3 SV=1 AAT1_BACSU - Aspartate aminotransferase OS=Bacillus subtilis (strain 168) GN=aspB PE=3 SV=1 gi\|221314475 - gi\|221314475\|ref\|ZP_03596280.1\| aspartate aminotransferase [Bacillus subtilis subsp. subtilis str. N... gi\|221319397 - gi\|221319397\|ref\|ZP_03600691.1\| aspartate aminotransferase [Bacillus subtilis subsp. subtilis str. J... gi\|221323673 - gi\|221323673\|ref\|ZP_03604967.1\| aspartate aminotransferase [Bacillus subtilis subsp. subtilis str. S...	278.0	[0..36]	[391..3]
gi\|48895332, gi\|... - gi\|71675283\|ref\|ZP_00673028.1\| Aminotransferase, class I and II [Trichodesmium erythraeum IMS101], g...	277.0	[0..36]	[391..3]
gi\|42780748, gi\|... - gi\|42780748\|ref\|NP_977995.1\| aspartate aminotransferase [Bacillus cereus ATCC 10987], gi\|42736668\|gb...	272.0	[0..36]	[390..3]
gi\|228984724, gi... - gi\|228984724\|ref\|ZP_04144896.1\| Aspartate aminotransferase [Bacillus thuringiensis serovar tochigien... gi\|228628337, gi... - gi\|229155210\|ref\|ZP_04283322.1\| Aspartate aminotransferase [Bacillus cereus ATCC 4342], gi\|228628337... gi\|47566009, gi\|... - gi\|47566009\|ref\|ZP_00237047.1\| aspartate aminotransferase [Bacillus cereus G9241], gi\|47556926\|gb\|EA...	271.0	[0..36]	[390..3]
gi\|118477096, gi... - gi\|118477096\|ref\|YP_894247.1\| aspartate aminotransferase [Bacillus thuringiensis str. Al Hakam], gi\|... gi\|167531298, gi... - gi\|167633260\|ref\|ZP_02391585.1\| aspartate aminotransferase [Bacillus anthracis str. A0442], gi\|16753... gi\|164714877, gi... - gi\|165869437\|ref\|ZP_02214096.1\| aspartate aminotransferase [Bacillus anthracis str. A0488], gi\|16471... gi\|225786881, gi... - gi\|225863508\|ref\|YP_002748886.1\| aspartate aminotransferase [Bacillus cereus 03BB102], gi\|225786881\|... gi\|227003591, gi... - gi\|227815608\|ref\|YP_002815617.1\| aspartate aminotransferase [Bacillus anthracis str. CDC 684], gi\|22... gi\|228914220, gi... - gi\|228914220\|ref\|ZP_04077836.1\| Aspartate aminotransferase [Bacillus thuringiensis serovar pulsiensi... gi\|228833051, gi... - gi\|228926675\|ref\|ZP_04089744.1\| Aspartate aminotransferase [Bacillus thuringiensis serovar pondicher... gi\|228826736, gi... - gi\|228932933\|ref\|ZP_04095798.1\| Aspartate aminotransferase [Bacillus thuringiensis serovar andalousi... gi\|228814479, gi... - gi\|228945244\|ref\|ZP_04107600.1\| Aspartate aminotransferase [Bacillus thuringiensis serovar monterrey... gi\|228662306, gi... - gi\|229121187\|ref\|ZP_04250424.1\| Aspartate aminotransferase [Bacillus cereus 95/8201], gi\|228662306\|g... gi\|228599688, gi... - gi\|229183839\|ref\|ZP_04311056.1\| Aspartate aminotransferase [Bacillus cereus BGSC 6E1], gi\|228599688\|... gi\|229266533, gi... - gi\|229602125\|ref\|YP_002866048.1\| aspartate aminotransferase [Bacillus anthracis str. A0248], gi\|2292... gi\|254723720 - gi\|254723720\|ref\|ZP_05185506.1\| aspartate aminotransferase [Bacillus anthracis str. A1055] gi\|254734481 - gi\|254734481\|ref\|ZP_05192193.1\| aspartate aminotransferase [Bacillus anthracis str. Western North Am... gi\|254740892 - gi\|254740892\|ref\|ZP_05198580.1\| aspartate aminotransferase [Bacillus anthracis str. Kruger B] gi\|170128600, gi... - gi\|170706502\|ref\|ZP_02896962.1\| aspartate aminotransferase [Bacillus anthracis str. A0389], gi\|17012... gi\|254755131 - gi\|254755131\|ref\|ZP_05207165.1\| aspartate aminotransferase [Bacillus anthracis str. Vollum] gi\|167639102, gi... - gi\|167639102\|ref\|ZP_02397375.1\| aspartate aminotransferase [Bacillus anthracis str. A0193], gi\|16751... gi\|254759668 - gi\|254759668\|ref\|ZP_05211692.1\| aspartate aminotransferase [Bacillus anthracis str. Australia 94] gi\|190568685, gi... - gi\|190568685\|ref\|ZP_03021590.1\| aspartate aminotransferase [Bacillus anthracis Tsiankovskii-I], gi\|1... gi\|172083508, gi... - gi\|177650364\|ref\|ZP_02933331.1\| aspartate aminotransferase [Bacillus anthracis str. A0174], gi\|17208... gi\|196030164, gi... - gi\|196039019\|ref\|ZP_03106326.1\| aspartate aminotransferase [Bacillus cereus NVH0597-99], gi\|19603016... gi\|195993859, gi... - gi\|196033425\|ref\|ZP_03100837.1\| aspartate aminotransferase [Bacillus cereus W], gi\|195993859\|gb\|EDX5... gi\|218902756, gi... - gi\|218902756\|ref\|YP_002450590.1\| aspartate aminotransferase [Bacillus cereus AH820], gi\|218539609\|gb... gi\|196046666, gi... - gi\|196046666\|ref\|ZP_03113890.1\| aspartate aminotransferase [Bacillus cereus 03BB108], gi\|196022599\|g... gi\|49332551, gi\|... - gi\|49480995\|ref\|YP_035760.1\| aspartate aminotransferase [Bacillus thuringiensis serovar konkukian st... gi\|52143804, gi\|... - gi\|52143804\|ref\|YP_083024.1\| aspartate aminotransferase [Bacillus cereus E33L], gi\|51977273\|gb\|AAU18... gi\|50082989, gi\|... - gi\|50196927\|ref\|YP_052621.1\| aspartate aminotransferase [Bacillus anthracis str. 'Ames Ancestor'], g... gi\|49184471, gi\|... - gi\|49184471\|ref\|YP_027723.1\| aspartate aminotransferase [Bacillus anthracis str. Sterne], gi\|4917839... gi\|21399462, gi\|... - gi\|65318911\|ref\|ZP_00391870.1\| COG0436: Aspartate/tyrosine/aromatic aminotransferase [Bacillus anthr... gi\|30255869, gi\|... - gi\|30261641\|ref\|NP_844018.1\| aspartate aminotransferase [Bacillus anthracis str. Ames], gi\|30255869\|...	271.0	[0..36]	[390..3]
gi\|56380549, gi\|... - gi\|56420707\|ref\|YP_148025.1\| aspartate aminotransferase [Geobacillus kaustophilus HTA426], gi\|563805...	270.0	[0..36]	[391..3]
gi\|163861658, gi... - gi\|89204918\|ref\|ZP_01183493.1\| Aminotransferase, class I and II [Bacillus weihenstephanensis KBAB4],... gi\|228617065, gi... - gi\|229166491\|ref\|ZP_04294247.1\| Aspartate aminotransferase [Bacillus cereus AH621], gi\|228617065\|gb\|... gi\|228651159, gi... - gi\|229132453\|ref\|ZP_04261307.1\| Aspartate aminotransferase [Bacillus cereus BDRD-ST196], gi\|22865115...	270.0	[0..36]	[390..3]
gi\|25315638 - pir\|\|G83861 aspartate aminotransferase aspB [imported] - Bacillus halodurans (strain C-125) gi\|10174312, gi\|... - gi\|15614258\|ref\|NP_242561.1\| aspartate aminotransferase [Bacillus halodurans C-125], gi\|10174312\|dbj...	269.0	[0..35]	[391..2]
gi\|89085004, gi\|... - gi\|89100266\|ref\|ZP_01173132.1\| hypothetical protein B14911_24581 [Bacillus sp. NRRL B-14911], gi\|890...	268.0	[0..37]	[391..8]

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Predicted Domain #1

Region A:
Residues: [1-391]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQEPICQEP MSNVTVRSVP SDNSASNPLD KIVIESATLA ARLARPELLE LTPYQSARRL  60
   61 GGKGDIWINA NESPFNNVAV GELDLTKLNR YPECQPPALI NAYSQYSGVV ESKIVASRGA 120
  121 DEAIELLIRA FCIPGIDSIA TFGPTYGMYA ISAQTFNVGV KALSLSAEYG LPADFATAAR 180
  181 GAKLVFICNP NNPTGTVIDK ARIEQAIQAL PDSIVVVDEA YIEFCPEYSV ADLLETYPNL 240
  241 VVLRTLSKAF ALAGARCGFL LANEEIIEII MRVIAPYPVP LPVSEVAEQA LSPAGIARMK 300
  301 TQVKELNTQG ERLAAALNLY CEQWGGAVLK PNGNYVLAEF DDVAKVAKLL TDNGIVARAY 360
  361 KDPRLAKAIR FSFSSQVDTD RLVSLFESQK R

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	57.69897
Match:	1fg3A
Description:	Histidinol-phosphate aminotransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.29878871754893	bayes_pls_golite062009
transferase activity, transferring nitrogenous groups	1.28316822767388	bayes_pls_golite062009
histidinol-phosphate transaminase activity	1.26617748508821	bayes_pls_golite062009
transaminase activity	1.24990480711889	bayes_pls_golite062009
transferase activity	0.737426388870721	bayes_pls_golite062009
intramolecular transferase activity, transferring amino groups	0.659071155545801	bayes_pls_golite062009
5-aminolevulinate synthase activity	0.604706675699046	bayes_pls_golite062009
L-aspartate:2-oxoglutarate aminotransferase activity	0.212525865555941	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: